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- References [13]
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- Product number
- ALX-804-364-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-364-C100, RRID:AB_11178278
- Product name
- Toll-like receptor 9 monoclonal antibody (26C593.2)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse, Rat, Canine, Horse, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 26C593.2
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides.
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Human lung cancer cells express functionally active Toll-like receptor 9.
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
Evidence of Toll-like receptor molecules on human platelets.
CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells.
Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.
Ewaschuk JB, Backer JL, Churchill TA, Obermeier F, Krause DO, Madsen KL
Infection and immunity 2007 May;75(5):2572-9
Infection and immunity 2007 May;75(5):2572-9
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides.
Martin-Armas M, Simon-Santamaria J, Pettersen I, Moens U, Smedsrød B, Sveinbjørnsson B
Journal of hepatology 2006 May;44(5):939-46
Journal of hepatology 2006 May;44(5):939-46
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B
Nature immunology 2006 Feb;7(2):156-64
Nature immunology 2006 Feb;7(2):156-64
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Lee J, Wu CC, Lee KJ, Chuang TH, Katakura K, Liu YT, Chan M, Tawatao R, Chung M, Shen C, Cottam HB, Lai MM, Raz E, Carson DA
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
Mansson A, Adner M, Cardell LO
Respiratory research 2006 Feb 27;7:36
Respiratory research 2006 Feb 27;7:36
TGF-alpha regulates TLR expression and function on epidermal keratinocytes.
Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
Journal of immunology (Baltimore, Md. : 1950) 2005 May 15;174(10):6137-43
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI
Leukemia research 2005 Jul;29(7):813-20
Leukemia research 2005 Jul;29(7):813-20
Human lung cancer cells express functionally active Toll-like receptor 9.
Droemann D, Albrecht D, Gerdes J, Ulmer AJ, Branscheid D, Vollmer E, Dalhoff K, Zabel P, Goldmann T
Respiratory research 2005 Jan 4;6:1
Respiratory research 2005 Jan 4;6:1
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S, O'neill SJ, McElvaney NG
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1638-46
Evidence of Toll-like receptor molecules on human platelets.
Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O
Immunology and cell biology 2005 Apr;83(2):196-8
Immunology and cell biology 2005 Apr;83(2):196-8
CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells.
Scheller C, Ullrich A, McPherson K, Hefele B, Knöferle J, Lamla S, Olbrich AR, Stocker H, Arasteh K, ter Meulen V, Rethwilm A, Koutsilieri E, Dittmer U
The Journal of biological chemistry 2004 May 21;279(21):21897-902
The Journal of biological chemistry 2004 May 21;279(21):21897-902
Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation.
Lee HK, Dunzendorfer S, Tobias PS
The Journal of biological chemistry 2004 Mar 12;279(11):10564-74
The Journal of biological chemistry 2004 Mar 12;279(11):10564-74
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of TLR9 using MAb to Toll-like Receptor 9 (human) (26C593.2) (Prod. No. ALX-804-364) at a dilution of 3µg/ml. A) human PBMC; B) human intestine; C) mouse intestine; D) rat intestine lysate;ÊE) human MCF7 cell lysate (MAb dilution 5µg/ml).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis: Formalin-fixed, paraffin-embedded human spleen probed with Toll-like receptor 9, mAb (26C593.2) at 5µg/ml.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Intracellular flow cytometric analysis of TLR9 in Ramos cells using 0.1µg MAb to Toll-like Receptor 9 (human) (26C593.2) (Prod. No. ALX-804-364). Shaded histogram represents Ramos cells without antibody; green represents isotype control (mouse IgG1); red represents MAb to Toll-like Receptor 9 (human) (26C593.2).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TLR9 in A) adenocarcinoma of the lung, C) A549 cells, and F) malignant lung tissues using MAb to Toll-like Receptor 9 (human) (26C593.2) (Prod. No. ALX-804-364) at 1:100 dilution, (600x magnification).
