Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19194-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19194-1-AP, RRID:AB_2215404
- Product name
- WDR45 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WDR45 antibody (Cat. #19194-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Iron Accumulation and Changes in Cellular Organelles in WDR45 Mutant Fibroblasts.
A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation.
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Lee HE, Jung MK, Noh SG, Choi HB, Chae SH, Lee JH, Mun JY
International journal of molecular sciences 2021 Oct 28;22(21)
International journal of molecular sciences 2021 Oct 28;22(21)
A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation.
Aring L, Choi EK, Kopera H, Lanigan T, Iwase S, Klionsky DJ, Seo YA
Journal of neurochemistry 2021 Nov 27;
Journal of neurochemistry 2021 Nov 27;
Early onset developmental delay and epilepsy in pediatric patients with WDR45 variants.
Chen H, Qian Y, Yu S, Xiao D, Guo X, Wang Q, Hao L, Yan K, Lu Y, Dong X, Zhou W, Wu B, Zhou S, Wang H
European journal of medical genetics 2019 Feb;62(2):149-160
European journal of medical genetics 2019 Feb;62(2):149-160
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using WDR45 antibody 19194-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 19194-1-AP(WDR45 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 19194-1-AP(WDR45 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue