Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 19497-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19497-1-AP, RRID:AB_10733222
- Product name
- FUT4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FUT4 antibody (Cat. #19497-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells.
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Neutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma.
FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.
Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.
Fucosyltransferase-4 and Oligosaccharide Lewis Y Antigen as potentially Correlative Biomarkers of Helicobacter pylori CagA Associated Gastric Cancer.
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.
Anti-LeY antibody enhances therapeutic efficacy of celecoxib against gastric cancer by downregulation of MAPKs/COX-2 signaling pathway: correlation with clinical study.
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.
Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression.
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, Wang X, Gao Y, Miao J, Guo C, Yang Y, Ni L, Liu L, Zhang S, Huang C
Cancer gene therapy 2020 Nov;27(10-11):773-784
Cancer gene therapy 2020 Nov;27(10-11):773-784
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Shan X, Dong W, Zhang L, Cai X, Zhao Y, Chen Q, Yan Q, Liu J
IUBMB life 2020 May;72(5):942-956
IUBMB life 2020 May;72(5):942-956
Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro.
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, Yang Z, Xu J, Zhang Y, Li L
Stem cells international 2019;2019:8035076
Stem cells international 2019;2019:8035076
Neutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma.
Li C, Zhao L, Wang Q, Ma S, Sun J, Ma C, Liu J, Jing X, Ai D, Nan Z, Qu X
Cancer management and research 2019;11:5171-5185
Cancer management and research 2019;11:5171-5185
FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.
Liu C, Li Z, Wang S, Fan Y, Zhang S, Yang X, Hou K, Tong J, Hu X, Shi X, Wang X, Liu Y, Che X, Qu X
Journal of cancer research and clinical oncology 2019 Jan;145(1):65-76
Journal of cancer research and clinical oncology 2019 Jan;145(1):65-76
Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells.
Zhu H, Wang H, Huang Q, Liu Q, Guo Y, Lu J, Li X, Xue C, Han Q
Frontiers in molecular neuroscience 2018;11:187
Frontiers in molecular neuroscience 2018;11:187
Directing Induced Pluripotent Stem Cell Derived Neural Stem Cell Fate with a Three-Dimensional Biomimetic Hydrogel for Spinal Cord Injury Repair.
Fan L, Liu C, Chen X, Zou Y, Zhou Z, Lin C, Tan G, Zhou L, Ning C, Wang Q
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
ACS applied materials & interfaces 2018 May 30;10(21):17742-17755
AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.
Zheng Q, Yang Y, Cui X, Zhang D, Liu S, Yan Q
Journal of cellular biochemistry 2018 Aug;119(8):6442-6451
Journal of cellular biochemistry 2018 Aug;119(8):6442-6451
Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.
He T, Qiu T, Wang X, Gui H, Wang X, Hu Q, Xia H, Qi G, Wu J, Ma H
OncoTargets and therapy 2017;10:195-203
OncoTargets and therapy 2017;10:195-203
Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.
Yu M, Wang J, Liu S, Wang X, Yan Q
Scientific reports 2017 Jul 13;7(1):5315
Scientific reports 2017 Jul 13;7(1):5315
miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans.
Zheng Q, Cui X, Zhang D, Yang Y, Yan X, Liu M, Niang B, Aziz F, Liu S, Yan Q, Liu J
Oncogenesis 2017 Jul 10;6(7):e358
Oncogenesis 2017 Jul 10;6(7):e358
Fucosyltransferase-4 and Oligosaccharide Lewis Y Antigen as potentially Correlative Biomarkers of Helicobacter pylori CagA Associated Gastric Cancer.
Aziz F, Gao W, Yan Q
Pathology oncology research : POR 2017 Jan;23(1):173-179
Pathology oncology research : POR 2017 Jan;23(1):173-179
MicroRNA-200c impairs uterine receptivity formation by targeting FUT4 and α1,3-fucosylation.
Zheng Q, Zhang D, Yang YU, Cui X, Sun J, Liang C, Qin H, Yang X, Liu S, Yan Q
Cell death and differentiation 2017 Dec;24(12):2161-2172
Cell death and differentiation 2017 Dec;24(12):2161-2172
Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.
Aziz F, Wang X, Liu J, Yan Q
Toxicology in vitro : an international journal published in association with BIBRA 2016 Mar;31:158-66
Toxicology in vitro : an international journal published in association with BIBRA 2016 Mar;31:158-66
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta-catenin signaling pathway.
Zhang YM, Zhang YY, Bulbul A, Shan X, Wang XQ, Yan Q
FEBS letters 2015 May 8;589(11):1225-33
FEBS letters 2015 May 8;589(11):1225-33
Anti-LeY antibody enhances therapeutic efficacy of celecoxib against gastric cancer by downregulation of MAPKs/COX-2 signaling pathway: correlation with clinical study.
Aziz F, Yang X, Wang X, Yan Q
Journal of cancer research and clinical oncology 2015 Jul;141(7):1221-35
Journal of cancer research and clinical oncology 2015 Jul;141(7):1221-35
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death.
Shan X, Tian LL, Zhang YM, Wang XQ, Yan Q, Liu JW
International journal of oncology 2015 Aug;47(2):701-9
International journal of oncology 2015 Aug;47(2):701-9
Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression.
Shan X, Aziz F, Tian LL, Wang XQ, Yan Q, Liu JW
International journal of oncology 2015 Apr;46(4):1667-76
International journal of oncology 2015 Apr;46(4):1667-76
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.
Yang X, Liu S, Yan Q
Cell death & disease 2013 Jul 25;4:e735
Cell death & disease 2013 Jul 25;4:e735
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 19497-1-AP(FUT4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FUT4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human FUT4. This antibody recognizes human antigen. The FUT4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.