FNab02835

antibody from FineTest Biotech
Targeting: ERCC6 ARMD5, CKN2, CSB, RAD26
Provider product page for FNab02835
Western blot
ELISA

Antibody data

Product number
FNab02835 - Provider product page
Provider
FineTest Biotech
Product name
ERCC6 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
excision repair cross-complementing
rodent repair deficiency, compleme
ntation group 6
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
ERCC6 protein structure - FNab02835 shown in red.