BS8126

antibody from Bioworld Technology, Inc
Targeting: UBE2V1 CROC-1, CROC1, UBE2V, UEV-1, UEV1A
Provider product page for BS8126
Western blot
Immunohistochemistry

Antibody data

Product number
BS8126 - Provider product page
Provider
Bioworld Technology, Inc
Product name
UBE2V1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human UBE2V1.
Description
Uev1A, also designated Uev1, UBE2V1 for Ubiquitin-conjugating enzyme E2 variant 1 and CROC1, shows sequence similarity to other ubiquitin-conjugating enzymes, but lacks the conserved cysteine residue critical for their catalytic activity . Therefore, Uev1A does not have ubiquitin-conjugating activity in vitro . However, constitutive expression of exogenous Uev1A in colon carcinoma cells inhibits their capacity to differentiate upon confluence. Studies on recombinant Uev1A show that it localizes to the nucleus, excluding the nucleolar regions . Uev1A functions with TRAF6, a RING domain protein, to catalyze the synthesis of unique polyubiquitin chains linked through lysine-63 of ubiquitin . The gene encoding Uev1A maps to human chromosome 20q13.2 .
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
UBE2V1 protein structure - BS8126 shown in red.