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- Antibody Data
- Antigen structure
- References [186]
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- Product number
- PA1239 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-GFAP Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for GFAP detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. GFAP information: Molecular Weight: 49880 MW; Subcellular Localization: Cytoplasm . Associated with intermediate filaments; Tissue Specificity: Expressed in cells lacking fibronectin.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus.
Transplantation of Wnt5a-modified Bone Marrow Mesenchymal Stem Cells Promotes Recovery After Spinal Cord Injury via the PI3K/AKT Pathway.
Cotransplantation of NSCs and ethyl stearate promotes synaptic plasticity in PD rats by Drd1/ERK/AP-1 signaling pathway.
Menthol-Modified Quercetin Liposomes with Brain-Targeting Function for the Treatment of Senescent Alzheimer's Disease.
Tauroursodeoxycholic Acid Inhibited Apoptosis and Oxidative Stress in H(2)O(2)-Induced BMSC Death via Modulating the Nrf-2 Signaling Pathway: the Therapeutic Implications in a Rat Model of Spinal Cord Injury.
Regulation of Microglial Activation by Wnt/β-Catenin Signaling After Global Cerebral Ischemia in Mice.
Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging.
Borneol-Modified Schisandrin B Micelles Cross the Blood-Brain Barrier To Treat Alzheimer's Disease in Aged Mice.
Transplantation of MiR-28-5p-Modified BMSCs Promotes Functional Recovery After Spinal Cord Injury.
GSDMD/Drp1 signaling pathway mediates hippocampal synaptic damage and neural oscillation abnormalities in a mouse model of sepsis-associated encephalopathy.
The neuroprotective effects of Liuwei Dihuang medicine in the APP/PS1 mouse model are dependent on the PI3K/Akt signaling pathway.
Inflachromene attenuates seizure severity in mouse epilepsy models via inhibiting HMGB1 translocation.
CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage.
Betulinic acid alleviates neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Vagus Nerve Stimulation Prevents Endothelial Necroptosis to Alleviate Blood-Spinal Cord Barrier Disruption After Spinal Cord Injury.
Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury.
Measurement of Patient-Derived Glioblastoma Cell Response to Temozolomide Using Fluorescence Lifetime Imaging of NAD(P)H.
Sex Differences in the Expression of Neuroimmune Molecules in the Spinal Cord of a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
Soy protein increases cognitive level in mice by modifying hippocampal nerve growth, oxidative stress, and intestinal microbiota.
Upregulation of SLITRK5 in patients with epilepsy and in a rat model.
A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury.
Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis.
CXCR4 knockout induces neuropathological changes in the MPTP-lesioned model of Parkinson's disease.
Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair.
Engineering of M2 Macrophages-Derived Exosomes via Click Chemistry for Spinal Cord Injury Repair.
A silk-based self-adaptive flexible opto-electro neural probe.
Vagus Nerve Stimulation Reduces Neuroinflammation Through Microglia Polarization Regulation to Improve Functional Recovery After Spinal Cord Injury.
Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch.
LiuweiDihuang improved cognitive functions in SAMP8 mice by inhibiting COX-2 expression and subsequent neuroinflammation.
Activated astrocytes attenuate neocortical seizures in rodent models through driving Na(+)-K(+)-ATPase.
Olfactory Ensheathing Cells Alleviate Facial Pain in Rats with Trigeminal Neuralgia by Inhibiting the Expression of P2X7 Receptor.
Hypoxia-stimulated mesenchymal stem cell-derived exosomes loaded by adhesive hydrogel for effective angiogenic treatment of spinal cord injury.
Stimulation by Exosomes from Hypoxia Preconditioned Human Umbilical Vein Endothelial Cells Facilitates Mesenchymal Stem Cells Angiogenic Function for Spinal Cord Repair.
Bu Shen Huo Xue decoction promotes functional recovery in spinal cord injury mice by improving the microenvironment to promote axonal regeneration.
Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemia.
A tannic acid doped hydrogel with small extracellular vesicles derived from mesenchymal stem cells promotes spinal cord repair by regulating reactive oxygen species microenvironment.
Protective effect of rapamycin in models of retinal degeneration.
Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response.
Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes.
Neuroinflammation changes with periodontal inflammation status during periodontitis in wild-type mice.
Injectable silk sericin scaffolds with programmable shape-memory property and neuro-differentiation-promoting activity for individualized brain repair of severe ischemic stroke.
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
Olfactory ensheathing cell transplantation alters the expression of chondroitin sulfate proteoglycans and promotes axonal regeneration after spinal cord injury.
Glial activation and inflammation in the NTS in a rat model after exposure to diesel exhaust particles.
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats.
Over-expression of arginine vasopressin in magnocellular neurosecretory cells of hypothalamus and its potential relationship with development of diabetic nephropathy.
Let-7f promotes the differentiation of neural stem cells in rats.
Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3.
(+)4-Cholesten-3-one promotes differentiation of neural stem cells into dopaminergic neurons through TET1 and FoxA2.
COX-2-PGE(2) signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice.
Participation of CXCL1 in the glial cells during neuropathic pain.
Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury.
Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70.
The temporal and spatial changes of microtubule cytoskeleton in the CA1 stratum radiatum following global transient ischemia.
Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy.
Safflower yellow attenuates learning and memory deficits in amyloid β-induced Alzheimer's disease rats by inhibiting neuroglia cell activation and inflammatory signaling pathways.
OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome.
PEDF protects human retinal pigment epithelial cells against oxidative stress via upregulation of UCP2 expression.
Spinal cord injury induced Neuregulin 1 signaling changes in mouse prefrontal cortex and hippocampus.
TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation.
Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury.
UCH-L1 inhibition aggravates mossy fiber sprouting in the pentylenetetrazole kindling model.
Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model.
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation.
The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse.
Time-course investigation of blood-brain barrier permeability and tight junction protein changes in a rat model of permanent focal ischemia.
Effects of long-term rapamycin treatment on glial scar formation after cryogenic traumatic brain injury in mice.
Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation.
A Small Organic Compound Mimicking the L1 Cell Adhesion Molecule Promotes Functional Recovery after Spinal Cord Injury in Zebrafish.
Inconsistence between number and function of autoreactive T cells in the course of experimental autoimmune encephalomyelitis.
The analgesic effect of early hyperbaric oxygen treatment in chronic constriction injury rats and its influence on nNOS and iNOS expression and inflammatory factor production.
Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone.
Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
Effects of safflower yellow on beta-amyloid deposition and activation of astrocytes in the brain of APP/PS1 transgenic mice.
The effects of calcineurin inhibitor FK506 on actin cytoskeleton, neuronal survival and glial reactions after pilocarpine-induced status epilepticus in mice.
Xanthoceraside attenuates amyloid β peptide(1-42)-induced memory impairments by reducing neuroinflammatory responses in mice.
Metalloprotease Adam10 suppresses epilepsy through repression of hippocampal neuroinflammation.
Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways.
Effects of electromagnetic pulse exposure on gelatinase of blood-brain barrier in vitro.
Gene silencing NMII promotes axonal regeneration against contusive spinal cord injury in rats.
CHL1 Is Expressed and Functions as a Malignancy Promoter in Glioma Cells.
Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
Neuregulin-1 protects mouse cerebellum against oxidative stress and neuroinflammation.
Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice.
Paeoniflorin attenuates the neuroinflammatory response in a rat model of chronic constriction injury.
Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.
Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.
A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
Synergistic effects of G-CSF and bone marrow stromal cells on nerve regeneration with acellular nerve xenografts.
Association of RASgrf1 methylation with epileptic seizures.
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats.
Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.
Intraventricular administration of urokinase as a novel therapeutic approach for communicating hydrocephalus.
Monocarboxylate Transporter 1 in the Medial Prefrontal Cortex Developmentally Expresses in Oligodendrocytes and Associates with Neuronal Amounts.
In Vitro Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like Cells by Cerebrospinal Fluid Improves Motor Function of Middle Cerebral Artery Occlusion Rats.
Analysis of the Expressions of TrkB and GLT-1 in Brain Tissues on a Rat Pentylenetetrazol Kindling Model of Chronic Epilepsy.
Cerebralcare Granule(®), a Chinese Herb Compound Preparation, Attenuates D-Galactose Induced Memory Impairment in Mice.
Expression of Glypican-4 in the brains of epileptic patients and epileptic animals and its effects on epileptic seizures.
Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model.
Activation of LILRB2 signal pathway in temporal lobe epilepsy patients and in a pilocarpine induced epilepsy model.
Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury.
Re-infection of the prion from the scrapie‑infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c.
Neuronal nitric oxide synthase contributes to pentylenetetrazole-kindling-induced hippocampal neurogenesis.
The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis.
Evaluation of the Combination of Methylprednisolone and Tranilast after Spinal Cord Injury in Rat Models.
Water-soluble ginseng oligosaccharides protect against scopolamine-induced cognitive impairment by functioning as an antineuroinflammatory agent.
Probenecid protects against oxygen-glucose deprivation injury in primary astrocytes by regulating inflammasome activity.
Elevated Expression of Acid-Sensing Ion Channel 3 Inhibits Epilepsy via Activation of Interneurons.
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Stereotactic injection of shrna GSK-3β-AAV promotes axonal regeneration after spinal cord injury.
Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium.
Brain Localization and Neurotoxicity Evaluation of Polysorbate 80-Modified Chitosan Nanoparticles in Rats.
Intensity-dependent effects of repetitive anodal transcranial direct current stimulation on learning and memory in a rat model of Alzheimer's disease.
Effect of siRNA-Livin on drug resistance to chemotherapy in glioma U251 cells and CD133(+) stem cells.
Cognitive deficits and anxiety induced by diisononyl phthalate in mice and the neuroprotective effects of melatonin.
Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation.
Peroxisome proliferator-activated receptor-γ agonist pioglitazone ameliorates white matter lesion and cognitive impairment in hypertensive rats.
Sulfiredoxin-1 protects primary cultured astrocytes from ischemia-induced damage.
Long-term tracing of the BrdU label-retaining cells in adult rat brain.
Effects of hypothermia on S100B and glial fibrillary acidic protein in asphyxia rats after cardiopulmonary resuscitation.
Galantamine attenuates amyloid-β deposition and astrocyte activation in APP/PS1 transgenic mice.
Lipoxin A4 Activates Nrf2 Pathway and Ameliorates Cell Damage in Cultured Cortical Astrocytes Exposed to Oxygen-Glucose Deprivation/Reperfusion Insults.
Chronic Noise Exposure Acts Cumulatively to Exacerbate Alzheimer's Disease-Like Amyloid-β Pathology and Neuroinflammation in the Rat Hippocampus.
Different methods for inducing adipose-derived stem cells to differentiate into Schwann-like cells.
Synergistic effects of Buyang Huanwu decoction and embryonic neural stem cell transplantation on the recovery of neurological function in a rat model of spinal cord injury.
Inhibition of adenosine monophosphate-activated protein kinase reduces glial cell-mediated inflammation and induces the expression of Cx43 in astroglias after cerebral ischemia.
Altered expression of hypoxia-Inducible factor-1α participates in the epileptogenesis in animal models.
Schisandrin A and B affect subventricular zone neurogenesis in mouse.
Neonatal intrahippocampal injection of lipopolysaccharide induces deficits in social behavior and prepulse inhibition and microglial activation in rats: Implication for a new schizophrenia animal model.
Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling.
Down-regulated expression of acid-sensing ion channel 1a in cortical lesions of patients with focal cortical dysplasia.
Altered expression of c-Abl in patients with epilepsy and in a rat model.
Systematic administration of B vitamins attenuates neuropathic hyperalgesia and reduces spinal neuron injury following temporary spinal cord ischaemia in rats.
Inhibition of Src phosphorylation reduces damage to the blood-brain barrier following transient focal cerebral ischemia in rats.
Morphology and functions of astrocytes cultured on water-repellent fractal tripalmitin surfaces.
Curcumin as a potential treatment for Alzheimer's disease: a study of the effects of curcumin on hippocampal expression of glial fibrillary acidic protein.
Selenoprotein S expression in the rat brain following focal cerebral ischemia.
Lanthanum chloride promotes mitochondrial apoptotic pathway in primary cultured rat astrocytes.
Effects of betamethasone on neuropathic pain in a rat spare nerve injury model.
Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia.
Effect of acupuncture on proliferation and differentiation of neural stem cells in brain tissues of rats with traumatic brain injury.
In vitro and in vivo study of dolichyl phosphate on the efflux activity of P-glycoprotein at the blood-brain barrier.
Tetramethylpyrazine (TMP) protects cerebral neurocytes and inhibits glioma by down regulating chemokine receptor CXCR4 expression.
The integration of NSC-derived and host neural networks after rat spinal cord transection.
Cuprizone-induced demyelination in mice: age-related vulnerability and exploratory behavior deficit.
Ketamine inhibits lipopolysaccharide-induced astrocytes activation by suppressing TLR4/NF-ĸB pathway.
Establishment of immortalized Schwann cells derived from rat embryo dorsal root ganglia.
Effect of periaqueductal gray melanocortin 4 receptor in pain facilitation and glial activation in rat model of chronic constriction injury.
Melanocortin 4 receptor antagonists attenuates morphine antinociceptive tolerance, astroglial activation and cytokines expression in the spinal cord of rat.
Cancer stem cell labeling using poly(L-lysine)-modified iron oxide nanoparticles.
Sciatic nerve repair by acellular nerve xenografts implanted with BMSCs in rats xenograft combined with BMSCs.
Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway.
Neural stem cells over-expressing brain-derived neurotrophic factor (BDNF) stimulate synaptic protein expression and promote functional recovery following transplantation in rat model of traumatic brain injury.
Differentiation of GDNF and NT-3 dual gene-modified rat bone marrow mesenchymal stem cells into enteric neuron-like cells.
Effect of sub-acute exposure to acrylamide on GABAergic neurons and astrocytes in weaning rat cerebellum.
Ipsilateral versus bilateral limb-training in promoting the proliferation and differentiation of endogenous neural stem cells following cerebral infarction in rats.
Transplanted olfactory ensheathing cells reduce retinal degeneration in Royal College of Surgeons rats.
Spatiotemporally controlled and multifactor involved assay of neuronal compartment regeneration after chemical injury in an integrated microfluidics.
Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection.
Brain histological changes in young mice submitted to diets with different ratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy and lactation.
Gypenosides improve cognitive impairment induced by chronic cerebral hypoperfusion in rats by suppressing oxidative stress and astrocytic activation.
A cascade targeting strategy for brain neuroglial cells employing nanoparticles modified with angiopep-2 peptide and EGFP-EGF1 protein.
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Müller cells in a rat model of retinitis pigmentosa.
Gypenoside attenuates white matter lesions induced by chronic cerebral hypoperfusion in rats.
Relationship between activated astrocytes and hypoxic cerebral tissue in a rat model of cerebral ischemia/reperfusion.
Amelioration of dementia induced by Aβ 22-35 through rectal delivery of undecapeptide-hEGF to mouse brain.
Retinal metabolic changes in an experimental model of optic nerve transection by ex vivo 1H magnetic resonance spectroscopy.
Establishment of hamster- and human-PRNP transgenic mice.
Induction of human bone marrow mesenchymal stem cells differentiation into neural-like cells using cerebrospinal fluid.
Protective effects of grape seed proanthocyanidin extracts on cerebral cortex of streptozotocin-induced diabetic rats through modulating AGEs/RAGE/NF-kappaB pathway.
Differentiation of neural stem cells into Schwann-like cells in vitro.
Effect of IKVAV peptide nanofiber on proliferation, adhesion and differentiation into neurocytes of bone marrow stromal cells.
A rat model for studying neural stem cell transplantation.
Vaccination with dendritic cells pulsed with homogenate protein of spinal cord promotes functional recovery from spinal cord injury in mice.
The effect of 3-hydroxybutyrate methyl ester on learning and memory in mice.
Chelation of GRP78 with lead and its localization changes in the astroglia of rats exposed to lead.
Adenoviral delivery of soluble VEGF receptor 1 (sFlt-1) inhibits experimental autoimmune encephalomyelitis in dark Agouti (DA) rats.
Long-Term in vitro expansion of retinal progenitor cells by culturing intact neurospheres in monolayer.
Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats.
Simultaneous expression of Oct4 and genes of three germ layers in single cell-derived multipotent adult progenitor cells.
Lead-induced stress response in endoplasmic reticulum of astrocytes in CNS.
Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases.
The effect of 3-hydroxybutyrate and its derivatives on the growth of glial cells.
Combination of adenoviral vector-mediated neurotrophin-3 gene transfer and retinoic acid promotes adult bone marrow cells to differentiate into neuronal phenotypes.
Wang T, Wu X, Zhao X, Li J, Yu J, Sheng M, Gao M, Cao Y, Wang J, Guo X, Zeng K
Journal of inflammation research 2024;17:1241-1253
Journal of inflammation research 2024;17:1241-1253
Transplantation of Wnt5a-modified Bone Marrow Mesenchymal Stem Cells Promotes Recovery After Spinal Cord Injury via the PI3K/AKT Pathway.
Yang H, Liang C, Luo J, Liu X, Wang W, Zheng K, Luo D, Hou Y, Guo D, Lin D, Zheng X, Li X
Molecular neurobiology 2024 May 25;
Molecular neurobiology 2024 May 25;
Cotransplantation of NSCs and ethyl stearate promotes synaptic plasticity in PD rats by Drd1/ERK/AP-1 signaling pathway.
Yi L, Ma H, Yang X, Zheng Q, Zhong J, Ye S, Li X, Chen D, Li H, Li C
Journal of ethnopharmacology 2024 Mar 1;321:117292
Journal of ethnopharmacology 2024 Mar 1;321:117292
Menthol-Modified Quercetin Liposomes with Brain-Targeting Function for the Treatment of Senescent Alzheimer's Disease.
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ACS chemical neuroscience 2024 Jun 5;15(11):2283-2295
ACS chemical neuroscience 2024 Jun 5;15(11):2283-2295
Tauroursodeoxycholic Acid Inhibited Apoptosis and Oxidative Stress in H(2)O(2)-Induced BMSC Death via Modulating the Nrf-2 Signaling Pathway: the Therapeutic Implications in a Rat Model of Spinal Cord Injury.
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Regulation of Microglial Activation by Wnt/β-Catenin Signaling After Global Cerebral Ischemia in Mice.
Liu J, Zhang X, Xu Y, Zhang S
Molecular neurobiology 2024 Jan;61(1):308-325
Molecular neurobiology 2024 Jan;61(1):308-325
Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging.
Li M, Guo H, Carey M, Huang C
Nature aging 2024 Jan;4(1):62-79
Nature aging 2024 Jan;4(1):62-79
Borneol-Modified Schisandrin B Micelles Cross the Blood-Brain Barrier To Treat Alzheimer's Disease in Aged Mice.
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ACS chemical neuroscience 2024 Feb 7;15(3):593-607
ACS chemical neuroscience 2024 Feb 7;15(3):593-607
Transplantation of MiR-28-5p-Modified BMSCs Promotes Functional Recovery After Spinal Cord Injury.
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Molecular neurobiology 2024 Apr;61(4):2197-2214
Molecular neurobiology 2024 Apr;61(4):2197-2214
GSDMD/Drp1 signaling pathway mediates hippocampal synaptic damage and neural oscillation abnormalities in a mouse model of sepsis-associated encephalopathy.
Fu Q, Zhang YB, Shi CX, Jiang M, Lu K, Fu ZH, Ruan JP, Wu J, Gu XP
Journal of neuroinflammation 2024 Apr 16;21(1):96
Journal of neuroinflammation 2024 Apr 16;21(1):96
The neuroprotective effects of Liuwei Dihuang medicine in the APP/PS1 mouse model are dependent on the PI3K/Akt signaling pathway.
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Frontiers in pharmacology 2023;14:1188893
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Inflachromene attenuates seizure severity in mouse epilepsy models via inhibiting HMGB1 translocation.
Dai SJ, Shao YY, Zheng Y, Sun JY, Li ZS, Shi JY, Yan MQ, Qiu XY, Xu CL, Cho WS, Nishibori M, Yi S, Park SB, Wang Y, Chen Z
Acta pharmacologica Sinica 2023 Sep;44(9):1737-1747
Acta pharmacologica Sinica 2023 Sep;44(9):1737-1747
CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage.
Luo X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Sep;32(9):107266
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Sep;32(9):107266
Betulinic acid alleviates neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
Sun Y, Yu F, Cao W, Zhang W, Liu W, Dai F
Neuroscience letters 2023 Sep 14;813:137429
Neuroscience letters 2023 Sep 14;813:137429
Vagus Nerve Stimulation Prevents Endothelial Necroptosis to Alleviate Blood-Spinal Cord Barrier Disruption After Spinal Cord Injury.
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Molecular neurobiology 2023 Nov;60(11):6466-6475
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Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury.
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Journal of nanobiotechnology 2023 Nov 27;21(1):451
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Measurement of Patient-Derived Glioblastoma Cell Response to Temozolomide Using Fluorescence Lifetime Imaging of NAD(P)H.
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Pharmaceuticals (Basel, Switzerland) 2023 May 26;16(6)
Pharmaceuticals (Basel, Switzerland) 2023 May 26;16(6)
Sex Differences in the Expression of Neuroimmune Molecules in the Spinal Cord of a Mouse Model of Antiretroviral-Induced Neuropathic Pain.
Al-HadlaQ MW, Masocha W
Biomedicines 2023 Mar 13;11(3)
Biomedicines 2023 Mar 13;11(3)
Soy protein increases cognitive level in mice by modifying hippocampal nerve growth, oxidative stress, and intestinal microbiota.
Dong B, Qi Y, Sundas H, Yang R, Zhou J, Li Z
Journal of the science of food and agriculture 2023 Jun;103(8):4085-4094
Journal of the science of food and agriculture 2023 Jun;103(8):4085-4094
Upregulation of SLITRK5 in patients with epilepsy and in a rat model.
Liu Y, Zhang L, Ai M, Xia D, Chen H, Pang R, Mei R, Zhong L, Chen L
Synapse (New York, N.Y.) 2023 Jul;77(4):e22266
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A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury.
Li Z, Zhao T, Ding J, Gu H, Wang Q, Wang Y, Zhang D, Gao C
Bioactive materials 2023 Jan;19:550-568
Bioactive materials 2023 Jan;19:550-568
Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis.
Lu X, Xu G, Lin Z, Zou F, Liu S, Zhang Y, Fu W, Jiang J, Ma X, Song J
Biomaterials research 2023 Jan 17;27(1):3
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CXCR4 knockout induces neuropathological changes in the MPTP-lesioned model of Parkinson's disease.
Ma J, Dong L, Chang Q, Chen S, Zheng J, Li D, Wu S, Yang H, Li X
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166597
Biochimica et biophysica acta. Molecular basis of disease 2023 Feb;1869(2):166597
Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair.
Xu L, Mu J, Ma Z, Lin P, Xia F, Hu X, Wu J, Cao J, Liu S, Huang T, Ling D, Gao J, Li F
ACS applied materials & interfaces 2023 Aug 9;15(31):37193-37204
ACS applied materials & interfaces 2023 Aug 9;15(31):37193-37204
Engineering of M2 Macrophages-Derived Exosomes via Click Chemistry for Spinal Cord Injury Repair.
Zeng J, Gu C, Sun Y, Chen X
Advanced healthcare materials 2023 Apr;12(11):e2203391
Advanced healthcare materials 2023 Apr;12(11):e2203391
A silk-based self-adaptive flexible opto-electro neural probe.
Zhou Y, Gu C, Liang J, Zhang B, Yang H, Zhou Z, Li M, Sun L, Tao TH, Wei X
Microsystems & nanoengineering 2022;8:118
Microsystems & nanoengineering 2022;8:118
Vagus Nerve Stimulation Reduces Neuroinflammation Through Microglia Polarization Regulation to Improve Functional Recovery After Spinal Cord Injury.
Chen H, Feng Z, Min L, Deng W, Tan M, Hong J, Gong Q, Zhang D, Liu H, Hou J
Frontiers in neuroscience 2022;16:813472
Frontiers in neuroscience 2022;16:813472
Mechanobiological responses of astrocytes in optic nerve head due to biaxial stretch.
Li Z, Peng F, Liu Z, Li S, Li L, Qian X
BMC ophthalmology 2022 Sep 16;22(1):368
BMC ophthalmology 2022 Sep 16;22(1):368
LiuweiDihuang improved cognitive functions in SAMP8 mice by inhibiting COX-2 expression and subsequent neuroinflammation.
Song J, Jia Y, Li J, Ding R, Yuan Y, Cai J, Su Y, Hua Q, Zhang Z
Journal of ethnopharmacology 2022 Oct 5;296:115491
Journal of ethnopharmacology 2022 Oct 5;296:115491
Activated astrocytes attenuate neocortical seizures in rodent models through driving Na(+)-K(+)-ATPase.
Zhao J, Sun J, Zheng Y, Zheng Y, Shao Y, Li Y, Fei F, Xu C, Liu X, Wang S, Ruan Y, Liu J, Duan S, Chen Z, Wang Y
Nature communications 2022 Nov 21;13(1):7136
Nature communications 2022 Nov 21;13(1):7136
Olfactory Ensheathing Cells Alleviate Facial Pain in Rats with Trigeminal Neuralgia by Inhibiting the Expression of P2X7 Receptor.
Lu J, Yang B, Liao J, Chen B, Lu M, Zhang W, Zeng J, Cheng H, Liu Z
Brain sciences 2022 May 30;12(6)
Brain sciences 2022 May 30;12(6)
Hypoxia-stimulated mesenchymal stem cell-derived exosomes loaded by adhesive hydrogel for effective angiogenic treatment of spinal cord injury.
Mu J, Li L, Wu J, Huang T, Zhang Y, Cao J, Ma T, Chen J, Zhang C, Zhang X, Lu T, Kong X, Sun J, Gao J
Biomaterials science 2022 Mar 29;10(7):1803-1811
Biomaterials science 2022 Mar 29;10(7):1803-1811
Stimulation by Exosomes from Hypoxia Preconditioned Human Umbilical Vein Endothelial Cells Facilitates Mesenchymal Stem Cells Angiogenic Function for Spinal Cord Repair.
Li L, Mu J, Zhang Y, Zhang C, Ma T, Chen L, Huang T, Wu J, Cao J, Feng S, Cai Y, Han M, Gao J
ACS nano 2022 Jul 26;16(7):10811-10823
ACS nano 2022 Jul 26;16(7):10811-10823
Bu Shen Huo Xue decoction promotes functional recovery in spinal cord injury mice by improving the microenvironment to promote axonal regeneration.
Hou Y, Luo D, Hou Y, Luan J, Zhan J, Chen Z, E S, Xu L, Lin D
Chinese medicine 2022 Jul 12;17(1):85
Chinese medicine 2022 Jul 12;17(1):85
Different changes in pre- and postsynaptic components in the hippocampal CA1 subfield after transient global cerebral ischemia.
Zhang Y, Tan BH, Wu S, Wu CH, Suo JL, Gui Y, Zhou CM, Li YC
Brain structure & function 2022 Jan;227(1):345-360
Brain structure & function 2022 Jan;227(1):345-360
A tannic acid doped hydrogel with small extracellular vesicles derived from mesenchymal stem cells promotes spinal cord repair by regulating reactive oxygen species microenvironment.
Liu Z, Guo S, Dong L, Wu P, Li K, Li X, Li X, Qian H, Fu Q
Materials today. Bio 2022 Dec;16:100425
Materials today. Bio 2022 Dec;16:100425
Protective effect of rapamycin in models of retinal degeneration.
Niu Z, Shi Y, Li J, Qiao S, Du S, Chen L, Tian H, Wei L, Cao H, Wang J, Gao L
Experimental eye research 2021 Sep;210:108700
Experimental eye research 2021 Sep;210:108700
Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response.
Hou Y, Luan J, Huang T, Deng T, Li X, Xiao Z, Zhan J, Luo D, Hou Y, Xu L, Lin D
Journal of neuroinflammation 2021 Sep 20;18(1):216
Journal of neuroinflammation 2021 Sep 20;18(1):216
Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes.
Mu J, Wu J, Cao J, Ma T, Li L, Feng S, Gao J
Asian journal of pharmaceutical sciences 2021 Nov;16(6):806-815
Asian journal of pharmaceutical sciences 2021 Nov;16(6):806-815
Neuroinflammation changes with periodontal inflammation status during periodontitis in wild-type mice.
Wang X, Tong Y, Zhang J, Khan N, Zhang K, Bai H, Zhang Q, Chen Y
Oral diseases 2021 May;27(4):1001-1011
Oral diseases 2021 May;27(4):1001-1011
Injectable silk sericin scaffolds with programmable shape-memory property and neuro-differentiation-promoting activity for individualized brain repair of severe ischemic stroke.
Wang J, Li X, Song Y, Su Q, Xiaohalati X, Yang W, Xu L, Cai B, Wang G, Wang Z, Wang L
Bioactive materials 2021 Jul;6(7):1988-1999
Bioactive materials 2021 Jul;6(7):1988-1999
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
Liu J, Zhang N, Zhang M, Yin H, Zhang X, Wang X, Wang X, Zhao Y
Experimental eye research 2021 Jul;208:108595
Experimental eye research 2021 Jul;208:108595
Olfactory ensheathing cell transplantation alters the expression of chondroitin sulfate proteoglycans and promotes axonal regeneration after spinal cord injury.
Wang GY, Cheng ZJ, Yuan PW, Li HP, He XJ
Neural regeneration research 2021 Aug;16(8):1638-1644
Neural regeneration research 2021 Aug;16(8):1638-1644
Glial activation and inflammation in the NTS in a rat model after exposure to diesel exhaust particles.
Chen Z, Chen F, Fang Z, Zhao H, Zhan C, Li C, He Y, Huang C, Long L, Lai K
Environmental toxicology and pharmacology 2021 Apr;83:103584
Environmental toxicology and pharmacology 2021 Apr;83:103584
Abnormal Glu/mGluR(2/3)/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression.
Liu J, Han YS, Liu L, Tang L, Yang H, Meng P, Zhao HQ, Wang YH
Neural regeneration research 2021 Apr;16(4):727-733
Neural regeneration research 2021 Apr;16(4):727-733
PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats.
Li J, Zhang K, Zhang Q, Zhou X, Wen L, Ma J, Niu L, Li C
BioMed research international 2020;2020:8163789
BioMed research international 2020;2020:8163789
Over-expression of arginine vasopressin in magnocellular neurosecretory cells of hypothalamus and its potential relationship with development of diabetic nephropathy.
Li X, Gao Z, Xu L, Li B, Gao H
Archives of medical science : AMS 2020;16(5):1130-1139
Archives of medical science : AMS 2020;16(5):1130-1139
Let-7f promotes the differentiation of neural stem cells in rats.
Deng Z, Wei Y, Yao Y, Gao S, Wang X
American journal of translational research 2020;12(9):5752-5761
American journal of translational research 2020;12(9):5752-5761
Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3.
Li X, Shi MQ, Chen C, Du JR
International immunopharmacology 2020 Sep;86:106714
International immunopharmacology 2020 Sep;86:106714
(+)4-Cholesten-3-one promotes differentiation of neural stem cells into dopaminergic neurons through TET1 and FoxA2.
Ye S, Zhong J, Huang J, Zhang S, Li H, Chen D, Li C
Neuroscience letters 2020 Sep 14;735:135239
Neuroscience letters 2020 Sep 14;735:135239
COX-2-PGE(2) signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice.
Zhu X, Yao Y, Yang J, Zhengxie J, Li X, Hu S, Zhang A, Dong J, Zhang C, Gan G
International immunopharmacology 2020 Oct;87:106801
International immunopharmacology 2020 Oct;87:106801
Participation of CXCL1 in the glial cells during neuropathic pain.
Moraes TR, Elisei LS, Malta IH, Galdino G
European journal of pharmacology 2020 May 15;875:173039
European journal of pharmacology 2020 May 15;875:173039
Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury.
Yang Z, Bao Y, Chen W, He Y
Neuropeptides 2020 Feb;79:102002
Neuropeptides 2020 Feb;79:102002
Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70.
Zhang L, Gao J, Chen T, Chen X, Ji X, Ye K, Yu J, Tang B, Wei Y, Xu H, Hu J
Stem cells international 2019;2019:6452684
Stem cells international 2019;2019:6452684
The temporal and spatial changes of microtubule cytoskeleton in the CA1 stratum radiatum following global transient ischemia.
Xiong TQ, Guo CY, Tan BH, Gui Y, Li YC
Journal of chemical neuroanatomy 2019 Nov;101:101682
Journal of chemical neuroanatomy 2019 Nov;101:101682
Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy.
Wen Y, Wu K, Xie Y, Dan W, Zhan Y, Shi Q
Biochemical and biophysical research communications 2019 Mar 26;511(1):79-86
Biochemical and biophysical research communications 2019 Mar 26;511(1):79-86
Safflower yellow attenuates learning and memory deficits in amyloid β-induced Alzheimer's disease rats by inhibiting neuroglia cell activation and inflammatory signaling pathways.
Zhang L, Zhou Z, Zhai W, Pang J, Mo Y, Yang G, Qu Z, Hu Y
Metabolic brain disease 2019 Jun;34(3):927-939
Metabolic brain disease 2019 Jun;34(3):927-939
OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome.
Xu R, Brawner AT, Li S, Liu JJ, Kim H, Xue H, Pang ZP, Kim WY, Hart RP, Liu Y, Jiang P
Cell stem cell 2019 Jun 6;24(6):908-926.e8
Cell stem cell 2019 Jun 6;24(6):908-926.e8
PEDF protects human retinal pigment epithelial cells against oxidative stress via upregulation of UCP2 expression.
Wang X, Liu X, Ren Y, Liu Y, Han S, Zhao J, Gou X, He Y
Molecular medicine reports 2019 Jan;19(1):59-74
Molecular medicine reports 2019 Jan;19(1):59-74
Spinal cord injury induced Neuregulin 1 signaling changes in mouse prefrontal cortex and hippocampus.
Xue WK, Zhao WJ, Meng XH, Shen HF, Huang PZ
Brain research bulletin 2019 Jan;144:180-186
Brain research bulletin 2019 Jan;144:180-186
TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation.
Zhou W, Zhao T, Du J, Ji G, Li X, Ji S, Tian W, Wang X, Hao A
Cell death & disease 2019 Feb 27;10(3):198
Cell death & disease 2019 Feb 27;10(3):198
Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury.
Li R, Sahu S, Schachner M
Restorative neurology and neuroscience 2018;36(4):469-483
Restorative neurology and neuroscience 2018;36(4):469-483
UCH-L1 inhibition aggravates mossy fiber sprouting in the pentylenetetrazole kindling model.
Wen Y, Wu Q, Shi Q, Xie Y, Dan W, Chen Y, Ma L
Biochemical and biophysical research communications 2018 Sep 18;503(4):2312-2318
Biochemical and biophysical research communications 2018 Sep 18;503(4):2312-2318
Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model.
Zhang L, Zhang L, Li L, Hölscher C
Neuropeptides 2018 Oct;71:70-80
Neuropeptides 2018 Oct;71:70-80
6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation.
Zhang F, Zhang JG, Yang W, Xu P, Xiao YL, Zhang HT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1523-1529
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1523-1529
The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse.
Sahu S, Li R, Kadeyala PK, Liu S, Schachner M
The Journal of nutritional biochemistry 2018 May;55:219-228
The Journal of nutritional biochemistry 2018 May;55:219-228
Time-course investigation of blood-brain barrier permeability and tight junction protein changes in a rat model of permanent focal ischemia.
Liu P, Zhang R, Liu D, Wang J, Yuan C, Zhao X, Li Y, Ji X, Chi T, Zou L
The journal of physiological sciences : JPS 2018 Mar;68(2):121-127
The journal of physiological sciences : JPS 2018 Mar;68(2):121-127
Effects of long-term rapamycin treatment on glial scar formation after cryogenic traumatic brain injury in mice.
Fan YY, Nan F, Guo BL, Liao Y, Zhang MS, Guo J, Niu BL, Liang YQ, Yang CH, Zhang Y, Zhang XP, Pang XF
Neuroscience letters 2018 Jun 21;678:68-75
Neuroscience letters 2018 Jun 21;678:68-75
Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation.
Yeung RK, Xiang ZH, Tsang SY, Li R, Ho TYC, Li Q, Hui CK, Sham PC, Qiao MQ, Xue H
Translational psychiatry 2018 Jul 17;8(1):128
Translational psychiatry 2018 Jul 17;8(1):128
A Small Organic Compound Mimicking the L1 Cell Adhesion Molecule Promotes Functional Recovery after Spinal Cord Injury in Zebrafish.
Sahu S, Zhang Z, Li R, Hu J, Shen H, Loers G, Shen Y, Schachner M
Molecular neurobiology 2018 Jan;55(1):859-878
Molecular neurobiology 2018 Jan;55(1):859-878
Inconsistence between number and function of autoreactive T cells in the course of experimental autoimmune encephalomyelitis.
Wan X, Pei W, Zhang Y, Zhang L, Shahzad KA, Xu T, Shen C
Immunological investigations 2018 Jan;47(1):1-17
Immunological investigations 2018 Jan;47(1):1-17
The analgesic effect of early hyperbaric oxygen treatment in chronic constriction injury rats and its influence on nNOS and iNOS expression and inflammatory factor production.
Ding Y, Yao P, Hong T, Li H, Zhu Y, Han Z, Zhou G
Molecular pain 2018 Jan-Dec;14:1744806918765837
Molecular pain 2018 Jan-Dec;14:1744806918765837
Neuroprotective effect of arctigenin against neuroinflammation and oxidative stress induced by rotenone.
Zhang N, Dou D, Ran X, Kang T
RSC advances 2018 Jan 9;8(5):2280-2292
RSC advances 2018 Jan 9;8(5):2280-2292
Neuroprotective effects of a triple GLP-1/GIP/glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
Tai J, Liu W, Li Y, Li L, Hölscher C
Brain research 2018 Jan 1;1678:64-74
Brain research 2018 Jan 1;1678:64-74
Effects of safflower yellow on beta-amyloid deposition and activation of astrocytes in the brain of APP/PS1 transgenic mice.
Shi XM, Zhang H, Zhou ZJ, Ruan YY, Pang J, Zhang L, Zhai W, Hu YL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:553-565
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Feb;98:553-565
The effects of calcineurin inhibitor FK506 on actin cytoskeleton, neuronal survival and glial reactions after pilocarpine-induced status epilepticus in mice.
Xiong TQ, Chen LM, Tan BH, Guo CY, Li YN, Zhang YF, Li SL, Zhao H, Li YC
Epilepsy research 2018 Feb;140:138-147
Epilepsy research 2018 Feb;140:138-147
Xanthoceraside attenuates amyloid β peptide(1-42)-induced memory impairments by reducing neuroinflammatory responses in mice.
Qi Y, Ji XF, Chi TY, Liu P, Jin G, Xu Q, Jiao Q, Wang LH, Zou LB
European journal of pharmacology 2018 Feb 5;820:18-30
European journal of pharmacology 2018 Feb 5;820:18-30
Metalloprotease Adam10 suppresses epilepsy through repression of hippocampal neuroinflammation.
Zhu X, Li X, Zhu M, Xu K, Yang L, Han B, Huang R, Zhang A, Yao H
Journal of neuroinflammation 2018 Aug 4;15(1):221
Journal of neuroinflammation 2018 Aug 4;15(1):221
Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways.
Xia R, Ji C, Zhang L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(3):987-998
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(3):987-998
Effects of electromagnetic pulse exposure on gelatinase of blood-brain barrier in vitro.
Zhou Y, Qiu LB, An GZ, Zhou JX, Du L, Ma YH, Guo GZ, Ding GR
Electromagnetic biology and medicine 2017;36(1):1-7
Electromagnetic biology and medicine 2017;36(1):1-7
Gene silencing NMII promotes axonal regeneration against contusive spinal cord injury in rats.
Ning G, Liu Y, Xu H, Li Y, Wu H, Wang X, Feng S
International journal of clinical and experimental pathology 2017;10(11):11345-11352
International journal of clinical and experimental pathology 2017;10(11):11345-11352
CHL1 Is Expressed and Functions as a Malignancy Promoter in Glioma Cells.
Yang Z, Xie Q, Hu CL, Jiang Q, Shen HF, Schachner M, Zhao WJ
Frontiers in molecular neuroscience 2017;10:324
Frontiers in molecular neuroscience 2017;10:324
Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina.
Chen P, Cai X, Yang Y, Chen Z, Qiu J, Yu N, Tang M, Wang Q, Ge J, Yu K, Zhuang J
Investigative ophthalmology & visual science 2017 Sep 1;58(11):4662-4669
Investigative ophthalmology & visual science 2017 Sep 1;58(11):4662-4669
Neuregulin-1 protects mouse cerebellum against oxidative stress and neuroinflammation.
Xu J, Hu C, Chen S, Shen H, Jiang Q, Huang P, Zhao W
Brain research 2017 Sep 1;1670:32-43
Brain research 2017 Sep 1;1670:32-43
Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice.
Wang Y, Lin C, Cao Y, Duan Z, Guan Z, Xu J, Zhu XQ, Xia C
Scientific reports 2017 Nov 30;7(1):16682
Scientific reports 2017 Nov 30;7(1):16682
Paeoniflorin attenuates the neuroinflammatory response in a rat model of chronic constriction injury.
Zhou J, Wang J, Li W, Wang C, Wu L, Zhang J
Molecular medicine reports 2017 May;15(5):3179-3185
Molecular medicine reports 2017 May;15(5):3179-3185
Matrine promotes NT3 expression in CNS cells in experimental autoimmune encephalomyelitis.
Zhang ML, Zhang XJ, Kang J, Zhang HJ, Chen XL, Liu N, Liu SQ, Ma WD, Zhang GX, Zhu L
Neuroscience letters 2017 May 10;649:100-106
Neuroscience letters 2017 May 10;649:100-106
Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.
Wang Y, Huang N, Li H, Liu S, Chen X, Yu S, Wu N, Bian XW, Shen HY, Li C, Xiao L
Oncotarget 2017 Jun 6;8(23):37511-37524
Oncotarget 2017 Jun 6;8(23):37511-37524
A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
Shi L, Zhang Z, Li L, Hölscher C
Behavioural brain research 2017 Jun 1;327:65-74
Behavioural brain research 2017 Jun 1;327:65-74
Synergistic effects of G-CSF and bone marrow stromal cells on nerve regeneration with acellular nerve xenografts.
Jia H, Wang Y, Wang T, Dong Y, Li WL, Li JP, Ma WZ, Tong XJ, He ZY
Synapse (New York, N.Y.) 2017 Jul;71(7)
Synapse (New York, N.Y.) 2017 Jul;71(7)
Association of RASgrf1 methylation with epileptic seizures.
Chen X, Peng X, Wang L, Fu X, Zhou JX, Zhu B, Luo J, Wang X, Xiao Z
Oncotarget 2017 Jul 11;8(28):46286-46297
Oncotarget 2017 Jul 11;8(28):46286-46297
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
Yu P, Wang L, Tang F, Zeng L, Zhou L, Song X, Jia W, Chen J, Yang Q
Molecular neurobiology 2017 Jan;54(1):212-226
Molecular neurobiology 2017 Jan;54(1):212-226
Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats.
Qu Z, Zhang J, Yang H, Gao J, Chen H, Liu C, Gao W
Journal of agricultural and food chemistry 2017 Jan 18;65(2):291-300
Journal of agricultural and food chemistry 2017 Jan 18;65(2):291-300
Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.
Liu C, Mei M, Li Q, Roboti P, Pang Q, Ying Z, Gao F, Lowe M, Bao S
Proceedings of the National Academy of Sciences of the United States of America 2017 Jan 10;114(2):346-351
Proceedings of the National Academy of Sciences of the United States of America 2017 Jan 10;114(2):346-351
Intraventricular administration of urokinase as a novel therapeutic approach for communicating hydrocephalus.
Feng Z, Tan Q, Tang J, Li L, Tao Y, Chen Y, Yang Y, Luo C, Feng H, Zhu G, Chen Q, Chen Z
Translational research : the journal of laboratory and clinical medicine 2017 Feb;180:77-90.e2
Translational research : the journal of laboratory and clinical medicine 2017 Feb;180:77-90.e2
Monocarboxylate Transporter 1 in the Medial Prefrontal Cortex Developmentally Expresses in Oligodendrocytes and Associates with Neuronal Amounts.
Zhang M, Ma Z, Qin H, Yao Z
Molecular neurobiology 2017 Apr;54(3):2315-2326
Molecular neurobiology 2017 Apr;54(3):2315-2326
In Vitro Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like Cells by Cerebrospinal Fluid Improves Motor Function of Middle Cerebral Artery Occlusion Rats.
Ye Y, Peng YR, Hu SQ, Yan XL, Chen J, Xu T
Frontiers in neurology 2016;7:183
Frontiers in neurology 2016;7:183
Analysis of the Expressions of TrkB and GLT-1 in Brain Tissues on a Rat Pentylenetetrazol Kindling Model of Chronic Epilepsy.
Liu J, Zeng Y, You C, Yang Z
Turkish neurosurgery 2016;26(5):736-43
Turkish neurosurgery 2016;26(5):736-43
Cerebralcare Granule(®), a Chinese Herb Compound Preparation, Attenuates D-Galactose Induced Memory Impairment in Mice.
Qu Z, Yang H, Zhang J, Huo L, Chen H, Li Y, Liu C, Gao W
Neurochemical research 2016 Sep;41(9):2199-214
Neurochemical research 2016 Sep;41(9):2199-214
Expression of Glypican-4 in the brains of epileptic patients and epileptic animals and its effects on epileptic seizures.
Xiong Y, Zhang Y, Zheng F, Yang Y, Xu X, Wang W, Zhu B, Wang X
Biochemical and biophysical research communications 2016 Sep 9;478(1):241-246
Biochemical and biophysical research communications 2016 Sep 9;478(1):241-246
Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model.
Mi G, Gao Y, Liu S, Ye E, Li Y, Jin X, Yang H, Yang Z
Cell cycle (Georgetown, Tex.) 2016 Oct 17;15(20):2780-91
Cell cycle (Georgetown, Tex.) 2016 Oct 17;15(20):2780-91
Activation of LILRB2 signal pathway in temporal lobe epilepsy patients and in a pilocarpine induced epilepsy model.
Yue J, Li W, Liang C, Chen B, Chen X, Wang L, Zang Z, Yu S, Liu S, Li S, Yang H
Experimental neurology 2016 Nov;285(Pt A):51-60
Experimental neurology 2016 Nov;285(Pt A):51-60
Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury.
Li G, Che MT, Zhang K, Qin LN, Zhang YT, Chen RQ, Rong LM, Liu S, Ding Y, Shen HY, Long SM, Wu JL, Ling EA, Zeng YS
Biomaterials 2016 Mar;83:233-48
Biomaterials 2016 Mar;83:233-48
Re-infection of the prion from the scrapie‑infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c.
Xiao K, Zhang BY, Zhang XM, Wang J, Chen C, Chen LN, Lv Y, Shi Q, Dong XP
International journal of molecular medicine 2016 Mar;37(3):716-26
International journal of molecular medicine 2016 Mar;37(3):716-26
Neuronal nitric oxide synthase contributes to pentylenetetrazole-kindling-induced hippocampal neurogenesis.
Zhu X, Dong J, Shen K, Bai Y, Chao J, Yao H
Brain research bulletin 2016 Mar;121:138-47
Brain research bulletin 2016 Mar;121:138-47
The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis.
Daugherty DJ, Chechneva O, Mayrhofer F, Deng W
Scientific reports 2016 Mar 1;6:22556
Scientific reports 2016 Mar 1;6:22556
Evaluation of the Combination of Methylprednisolone and Tranilast after Spinal Cord Injury in Rat Models.
Mbori NJ, Chuan XY, Feng QX, Alizada M, Zhan J
Journal of Korean Neurosurgical Society 2016 Jul;59(4):334-40
Journal of Korean Neurosurgical Society 2016 Jul;59(4):334-40
Water-soluble ginseng oligosaccharides protect against scopolamine-induced cognitive impairment by functioning as an antineuroinflammatory agent.
Xu T, Shen X, Yu H, Sun L, Lin W, Zhang C
Journal of ginseng research 2016 Jul;40(3):211-9
Journal of ginseng research 2016 Jul;40(3):211-9
Probenecid protects against oxygen-glucose deprivation injury in primary astrocytes by regulating inflammasome activity.
Jian Z, Ding S, Deng H, Wang J, Yi W, Wang L, Zhu S, Gu L, Xiong X
Brain research 2016 Jul 15;1643:123-9
Brain research 2016 Jul 15;1643:123-9
Elevated Expression of Acid-Sensing Ion Channel 3 Inhibits Epilepsy via Activation of Interneurons.
Cao Q, Wang W, Gu J, Jiang G, Wang K, Xu Z, Li J, Chen G, Wang X
Molecular neurobiology 2016 Jan;53(1):485-498
Molecular neurobiology 2016 Jan;53(1):485-498
Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro.
Hu Y, Zhang Y, Tian K, Xun C, Wang S, Lv D
Molecular medicine reports 2016 Jan;13(1):49-58
Molecular medicine reports 2016 Jan;13(1):49-58
Stereotactic injection of shrna GSK-3β-AAV promotes axonal regeneration after spinal cord injury.
Zuo YC, Xiong NX, Zhao HY
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016 Aug;36(4):548-553
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2016 Aug;36(4):548-553
Label-retaining assay enriches tumor-initiating cells in glioblastoma spheres cultivated in serum-free medium.
Zeng L, Zhao Y, Ouyang T, Zhao T, Zhang S, Chen J, Yu J, Lei T
Oncology letters 2016 Aug;12(2):815-824
Oncology letters 2016 Aug;12(2):815-824
Brain Localization and Neurotoxicity Evaluation of Polysorbate 80-Modified Chitosan Nanoparticles in Rats.
Yuan ZY, Hu YL, Gao JQ
PloS one 2015;10(8):e0134722
PloS one 2015;10(8):e0134722
Intensity-dependent effects of repetitive anodal transcranial direct current stimulation on learning and memory in a rat model of Alzheimer's disease.
Yu X, Li Y, Wen H, Zhang Y, Tian X
Neurobiology of learning and memory 2015 Sep;123:168-78
Neurobiology of learning and memory 2015 Sep;123:168-78
Effect of siRNA-Livin on drug resistance to chemotherapy in glioma U251 cells and CD133(+) stem cells.
Liu Y, Guo Q, Zhang H, Li GH, Feng S, Yu XZ, Kong LS, Zhao L, Jin F
Experimental and therapeutic medicine 2015 Oct;10(4):1317-1323
Experimental and therapeutic medicine 2015 Oct;10(4):1317-1323
Cognitive deficits and anxiety induced by diisononyl phthalate in mice and the neuroprotective effects of melatonin.
Ma P, Liu X, Wu J, Yan B, Zhang Y, Lu Y, Wu Y, Liu C, Guo J, Nanberg E, Bornehag CG, Yang X
Scientific reports 2015 Oct 1;5:14676
Scientific reports 2015 Oct 1;5:14676
Histamine promotes locomotion recovery after spinal cord hemisection via inhibiting astrocytic scar formation.
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Neuroscience letters 2006 Nov 13;408(2):98-103
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- Main image
- Experimental details
- Western blot analysis of GFAP using anti- GFAP antibody (PA1239). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: Rat Brain Tissue Lysate, Lane 2: Mouse Brain Tissue Lysate, Lane 3: U87 Whole Cell Lysate. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- GFAP antigen affinity purified polyclonal antibody (Catalog # PA1239) at 0.5 μg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GFAP at approximately 49 KD. The expected band size for GFAP is at 49 KD.
- Additional image
