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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [32]
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- Validations
- Western blot [4]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN152487 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Glial Fibrillary Acidic Protein (GFAP) antibody
- Antibody type
- Polyclonal
- Description
- Unpurified
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Feline, Guinea Pig, Porcine, Rabbit
- Host
- Rabbit
- Vial size
- 0.05 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model.
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs.
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence.
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
Pathophysiological role of microRNA-29 in pancreatic cancer stroma.
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.
Adeno-associated virus mediated delivery of a non-membrane targeted human soluble CD59 attenuates some aspects of diabetic retinopathy in mice.
Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas.
Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro.
Effect of botulinum toxin A on the intraocular pressure and the retina in an animal model.
KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo.
Generation of neural cells from DM1 induced pluripotent stem cells as cellular model for the study of central nervous system neuropathogenesis.
Immune clearance of attenuated rabies virus results in neuronal survival with altered gene expression.
Hypoxic preconditioning involves system Xc- regulation in mouse neural stem cells.
Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology.
Postnatal morphine administration alters hippocampal development in rats.
STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice.
Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice.
Transplanted neurally modified bone marrow-derived mesenchymal stem cells promote tissue protection and locomotor recovery in spinal cord injured rats.
An inverted method for culturing dissociated mouse hippocampal neurons.
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool.
Molecular anatomy of the hair cell's ribbon synapse.
Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions.
Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK.
Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia.
Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development.
Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence.
Jurga AM, Piotrowska A, Makuch W, Przewlocka B, Mika J
Frontiers in pharmacology 2017;8:48
Frontiers in pharmacology 2017;8:48
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Fil D, DeLoach A, Yadav S, Alkam D, MacNicol M, Singh A, Compadre CM, Goellner JJ, O'Brien CA, Fahmi T, Basnakian AG, Calingasan NY, Klessner JL, Beal FM, Peters OM, Metterville J, Brown RH Jr, Ling KKY, Rigo F, Ozdinler PH, Kiaei M
Human molecular genetics 2017 Feb 15;26(4):686-701
Human molecular genetics 2017 Feb 15;26(4):686-701
Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs.
Kenig S, Faoro V, Bourkoula E, Podergajs N, Ius T, Vindigni M, Skrap M, Lah T, Cesselli D, Storici P, Vindigni A
Cancer cell international 2016;16:58
Cancer cell international 2016;16:58
Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
Zychowska M, Rojewska E, Makuch W, Luvisetto S, Pavone F, Marinelli S, Przewlocka B, Mika J
European journal of pharmacology 2016 Nov 15;791:377-388
European journal of pharmacology 2016 Nov 15;791:377-388
Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.
Pilat D, Piotrowska A, Rojewska E, Jurga A, Ślusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J
Molecular and cellular neurosciences 2016 Mar;71:114-24
Molecular and cellular neurosciences 2016 Mar;71:114-24
Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence.
Piotrowska A, Kwiatkowski K, Rojewska E, Slusarczyk J, Makuch W, Basta-Kaim A, Przewlocka B, Mika J
Journal of neuroimmunology 2016 Aug 15;297:9-19
Journal of neuroimmunology 2016 Aug 15;297:9-19
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
Popiolek-Barczyk K, Kolosowska N, Piotrowska A, Makuch W, Rojewska E, Jurga AM, Pilat D, Mika J
Neural plasticity 2015;2015:676473
Neural plasticity 2015;2015:676473
Pathophysiological role of microRNA-29 in pancreatic cancer stroma.
Kwon JJ, Nabinger SC, Vega Z, Sahu SS, Alluri RK, Abdul-Sater Z, Yu Z, Gore J, Nalepa G, Saxena R, Korc M, Kota J
Scientific reports 2015 Jun 22;5:11450
Scientific reports 2015 Jun 22;5:11450
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.
Anzilotti S, Tornincasa M, Gerlini R, Conte A, Brancaccio P, Cuomo O, Bianco G, Fusco A, Annunziato L, Pignataro G, Pierantoni GM
Cell death & disease 2015 Dec 3;6:e2004
Cell death & disease 2015 Dec 3;6:e2004
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.
Northcott PA, Lee C, Zichner T, Stütz AM, Erkek S, Kawauchi D, Shih DJ, Hovestadt V, Zapatka M, Sturm D, Jones DT, Kool M, Remke M, Cavalli FM, Zuyderduyn S, Bader GD, VandenBerg S, Esparza LA, Ryzhova M, Wang W, Wittmann A, Stark S, Sieber L, Seker-Cin H, Linke L, Kratochwil F, Jäger N, Buchhalter I, Imbusch CD, Zipprich G, Raeder B, Schmidt S, Diessl N, Wolf S, Wiemann S, Brors B, Lawerenz C, Eils J, Warnatz HJ, Risch T, Yaspo ML, Weber UD, Bartholomae CC, von Kalle C, Turányi E, Hauser P, Sanden E, Darabi A, Siesjö P, Sterba J, Zitterbart K, Sumerauer D, van Sluis P, Versteeg R, Volckmann R, Koster J, Schuhmann MU, Ebinger M, Grimes HL, Robinson GW, Gajjar A, Mynarek M, von Hoff K, Rutkowski S, Pietsch T, Scheurlen W, Felsberg J, Reifenberger G, Kulozik AE, von Deimling A, Witt O, Eils R, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Korbel JO, Wechsler-Reya RJ, Pfister SM
Nature 2014 Jul 24;511(7510):428-34
Nature 2014 Jul 24;511(7510):428-34
Adeno-associated virus mediated delivery of a non-membrane targeted human soluble CD59 attenuates some aspects of diabetic retinopathy in mice.
Adhi M, Cashman SM, Kumar-Singh R
PloS one 2013;8(10):e79661
PloS one 2013;8(10):e79661
Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas.
Ghods AJ, Glick R, Braun D, Feinstein D
Surgical neurology international 2013;4:160
Surgical neurology international 2013;4:160
Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro.
Xia G, Santostefano K, Hamazaki T, Liu J, Subramony SH, Terada N, Ashizawa T
Journal of molecular neuroscience : MN 2013 Oct;51(2):237-48
Journal of molecular neuroscience : MN 2013 Oct;51(2):237-48
Effect of botulinum toxin A on the intraocular pressure and the retina in an animal model.
Gatzioufas Z, Stupp T, Moschos MM, Kopsidas K, Charalambous P, Thanos S
Cutaneous and ocular toxicology 2013 Jun;32(2):107-11
Cutaneous and ocular toxicology 2013 Jun;32(2):107-11
KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo.
D'Alessandro G, Catalano M, Sciaccaluga M, Chece G, Cipriani R, Rosito M, Grimaldi A, Lauro C, Cantore G, Santoro A, Fioretti B, Franciolini F, Wulff H, Limatola C
Cell death & disease 2013 Aug 15;4:e773
Cell death & disease 2013 Aug 15;4:e773
Generation of neural cells from DM1 induced pluripotent stem cells as cellular model for the study of central nervous system neuropathogenesis.
Xia G, Santostefano KE, Goodwin M, Liu J, Subramony SH, Swanson MS, Terada N, Ashizawa T
Cellular reprogramming 2013 Apr;15(2):166-77
Cellular reprogramming 2013 Apr;15(2):166-77
Immune clearance of attenuated rabies virus results in neuronal survival with altered gene expression.
Gomme EA, Wirblich C, Addya S, Rall GF, Schnell MJ
PLoS pathogens 2012;8(10):e1002971
PLoS pathogens 2012;8(10):e1002971
Hypoxic preconditioning involves system Xc- regulation in mouse neural stem cells.
Sims B, Clarke M, Francillion L, Kindred E, Hopkins ES, Sontheimer H
Stem cell research 2012 Mar;8(2):285-91
Stem cell research 2012 Mar;8(2):285-91
Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology.
Wu K, Li S, Bodhinathan K, Meyers C, Chen W, Campbell-Thompson M, McIntyre L, Foster TC, Muzyczka N, Kumar A
Neurobiology of learning and memory 2012 Jan;97(1):69-80
Neurobiology of learning and memory 2012 Jan;97(1):69-80
Postnatal morphine administration alters hippocampal development in rats.
Traudt CM, Tkac I, Ennis KM, Sutton LM, Mammel DM, Rao R
Journal of neuroscience research 2012 Jan;90(1):307-14
Journal of neuroscience research 2012 Jan;90(1):307-14
STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice.
O'Donnell LA, Conway S, Rose RW, Nicolas E, Slifker M, Balachandran S, Rall GF
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1915-23
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1915-23
Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice.
Obara I, Tochiki KK, Géranton SM, Carr FB, Lumb BM, Liu Q, Hunt SP
Pain 2011 Nov;152(11):2582-95
Pain 2011 Nov;152(11):2582-95
Transplanted neurally modified bone marrow-derived mesenchymal stem cells promote tissue protection and locomotor recovery in spinal cord injured rats.
Alexanian AR, Fehlings MG, Zhang Z, Maiman DJ
Neurorehabilitation and neural repair 2011 Nov-Dec;25(9):873-80
Neurorehabilitation and neural repair 2011 Nov-Dec;25(9):873-80
An inverted method for culturing dissociated mouse hippocampal neurons.
Chen WS, Yueh CY, Huang YA, Hwang E
Neuroscience research 2011 May;70(1):118-23
Neuroscience research 2011 May;70(1):118-23
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
Poole DP, Pelayo JC, Cattaruzza F, Kuo YM, Gai G, Chiu JV, Bron R, Furness JB, Grady EF, Bunnett NW
Gastroenterology 2011 Aug;141(2):565-75, 575.e1-4
Gastroenterology 2011 Aug;141(2):565-75, 575.e1-4
Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool.
Marroquin Belaunzaran O, Cordero MI, Setola V, Bianchi S, Galli C, Bouche N, Mlynarik V, Gruetter R, Sandi C, Bensadoun JC, Molinari M, Aebischer P
PloS one 2011 Apr 20;6(4):e18268
PloS one 2011 Apr 20;6(4):e18268
Molecular anatomy of the hair cell's ribbon synapse.
Uthaiah RC, Hudspeth AJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12387-99
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Sep 15;30(37):12387-99
Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions.
Wu Q, Howell MP, Palmiter RD
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Sep 10;28(37):9218-26
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Sep 10;28(37):9218-26
Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK.
Maezawa I, Nivison M, Montine KS, Maeda N, Montine TJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Apr;20(6):797-9
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Apr;20(6):797-9
Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia.
Li Y, Fu L, Gonzales DM, Lavi E
Journal of virology 2004 Apr;78(7):3398-406
Journal of virology 2004 Apr;78(7):3398-406
Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development.
Henion TR, Qu Q, Smith FI
Brain research. Molecular brain research 2003 Apr 10;112(1-2):177-81
Brain research. Molecular brain research 2003 Apr 10;112(1-2):177-81
Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence.
Bignami A, Eng LF, Dahl D, Uyeda CT
Brain research 1972 Aug 25;43(2):429-35
Brain research 1972 Aug 25;43(2):429-35
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- antibodies-online (provider)
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- Submitted by
- antibodies-online (provider)
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Supportive validation
- Submitted by
- antibodies-online (provider)
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- Staining of typical astrocytic cells using ABIN152487 in neurons and glia of rat forebrain.
Supportive validation
- Submitted by
- antibodies-online (provider)
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- IHC
