BS7614

antibody from Bioworld Technology, Inc
Targeting: UGT1A4 HUG-BR2, UGT1D
Provider product page for BS7614
Western blot
Immunohistochemistry

Antibody data

Product number
BS7614 - Provider product page
Provider
Bioworld Technology, Inc
Product name
UGT1A4 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human UGT1A4.
Description
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
UGT1A4 protein structure - BS7614 shown in red.