Antibody data

Product number
BS7798
Provider
Bioworld Technology, Inc
Product name
TNFRSF13B polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS7798
Antibody type
Polyclonal
Antigen
Recombinant full length Human TNFRSF13B.
Description
The NFAT (nuclear factor of activated T cells) family of transcription factors regulates cytokine expression in T cells through cis-acting elements located in the promoters of the cytokine genes. The NFAT family consists of the cytoplasmic NFAT (NFATc), transcription factors NFATc1, NFATc2, NFATc3 and NFATc4, and nuclear NFAT (NFATn). Each of these transcription factors plays a role in T cell activation. CAML (calcium-signal modulating cyclophilin ligand) has been identified as an activator of NFAT and NF-IL2A when overexpressed in Jurkat cells. CAML has also been shown to activate calcineurin by causing calcium influx. TACI (transmembrane activator and CAML-interactor), a member of the TNF receptor superfamily, was identified based on its capacity to bind to CAML and has been shown to induce activation of NFAT in the presence of CAML.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -