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Immunocytochemistry
Immunohistochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-800-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-800-C100, RRID:AB_2052625
- Product name
- TACI (mouse) monoclonal antibody (8F10)
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Mouse
- Host
- Rat
- Isotype
- IgG
- Antibody clone number
- 8F10
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo.
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.
Diaz-de-Durana Y, Mantchev GT, Bram RJ, Franco A
Blood 2006 Jan 15;107(2):594-601
Blood 2006 Jan 15;107(2):594-601
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.
Huntington ND, Xu Y, Puthalakath H, Light A, Willis SN, Strasser A, Tarlinton DM
Nature immunology 2006 Feb;7(2):190-8
Nature immunology 2006 Feb;7(2):190-8
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.
Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, Mackay CR
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):807-17
Journal of immunology (Baltimore, Md. : 1950) 2004 Jul 15;173(2):807-17
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.
Batten M, Fletcher C, Ng LG, Groom J, Wheway J, Laâbi Y, Xin X, Schneider P, Tschopp J, Mackay CR, Mackay F
Journal of immunology (Baltimore, Md. : 1950) 2004 Jan 15;172(2):812-22
Journal of immunology (Baltimore, Md. : 1950) 2004 Jan 15;172(2):812-22
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Method: HEK 293Tcells were mock transfected (thin line) or transfected with an expression plasmid enabling surface expression of the extracellular domain of mouse TACI (thick line). Cells (5 x 10E5) were incubated on ice for 30 min in 50 µl FACS buffer (PBS, 5% Fetal calf serum, 0.02% azide) containing 1µg/ml of rat anti-mTACI 8F10 MAb. After washing in FACS buffer, R-PE-conjugated antibody to rat IgG (Prod. No. ALX-211-053) was added. Cells were incubated on ice for 30 min, washed and then analyzed by flow cytometry.
