Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00000191-M07A - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#H00000191-M07A, RRID:AB_1111658
- Product name
- AHCY monoclonal antibody (M07A), clone 4H2
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against a full length recombinant AHCY.
- Antigen sequence
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRM
RERYSASKPLKGARIAGCLHMTVETAVLIETLVTL
GAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGE
TDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIH
TKHPQLLPGIRGISEETTTGVHNLYKMMANGILKV
PAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVM
IAGKVAVVAGYGDVGKGCAQALRGFGARVIITEID
PINALQAAMEGYEVTTMDEACQEGNIFVTTTGCID
IILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENA
VEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCA
MGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHF
LPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY- Isotype
- IgM
- Antibody clone number
- 4H2
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Submitted references Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells.
S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation.
Chayka O, D'Acunto CW, Middleton O, Arab M, Sala A
The Journal of biological chemistry 2015 Jan 23;290(4):2198-212
The Journal of biological chemistry 2015 Jan 23;290(4):2198-212
S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation.
Fernandez-Sanchez ME, Gonatopoulos-Pournatzis T, Preston G, Lawlor MA, Cowling VH
Molecular and cellular biology 2009 Dec;29(23):6182-91
Molecular and cellular biology 2009 Dec;29(23):6182-91
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- AHCY monoclonal antibody (M07A), clone 4H2 Western Blot analysis of AHCY expression in A-549 ( Cat # L025V1 ).