abx012114

antibody from Abbexa

Targeting: TDGF1 CR, CR-1, CRIPTO, Cripto-1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx012114

Provider

Abbexa

Product name

Teratocarcinoma Derived Growth Factor 1 (TDGF1) Antibody

Antibody type

Monoclonal

Description

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.