Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN1450126 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NK2 Homeobox 1 (NKX2-1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- 16 amino acid synthetic peptide near the amino terminus of Human NKX2-1
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas.
Mutations in TITF-1 are associated with benign hereditary chorea.
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.
Kondo T, Nakazawa T, Ma D, Niu D, Mochizuki K, Kawasaki T, Nakamura N, Yamane T, Kobayashi M, Katoh R
Laboratory investigation; a journal of technical methods and pathology 2009 Jul;89(7):791-9
Laboratory investigation; a journal of technical methods and pathology 2009 Jul;89(7):791-9
Mutations in TITF-1 are associated with benign hereditary chorea.
Breedveld GJ, van Dongen JW, Danesino C, Guala A, Percy AK, Dure LS, Harper P, Lazarou LP, van der Linde H, Joosse M, GrĂ¼ters A, MacDonald ME, de Vries BB, Arts WF, Oostra BA, Krude H, Heutink P
Human molecular genetics 2002 Apr 15;11(8):971-9
Human molecular genetics 2002 Apr 15;11(8):971-9
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.
Lazzaro D, Price M, de Felice M, Di Lauro R
Development (Cambridge, England) 1991 Dec;113(4):1093-104
Development (Cambridge, England) 1991 Dec;113(4):1093-104
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.
Guazzi S, Price M, De Felice M, Damante G, Mattei MG, Di Lauro R
The EMBO journal 1990 Nov;9(11):3631-9
The EMBO journal 1990 Nov;9(11):3631-9
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of NKX2-1 in rat lung tissue lysate with NKX2-1 antibody at (A) 1 and (B) 2 ug/mL.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of NKX2-1 in human lung tissue with NKX2-1 antibody at 2.5 ug/mL.