BS60972

antibody from Bioworld Technology, Inc
Targeting: IL36RN FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840
Provider product page for BS60972

Antibody data

Product number
BS60972 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL36RN polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human IL36RN.
Description
IL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NF°ÙB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F5, also known as IL-1Ñ´, IL-1 like protein 1 (IL-1L1), IL-1HY1, IL-1ra (receptor antagonist) homolog 1 or IL-1 related protein 3 (IL-1rp3), is a secreted ligand belonging to this superfamily. IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similarly lacks the loop between the fourth and fifth ¡Â-strands. IL-1F5 acts as an antagonist, inhibiting the IL-1F9 activation of NF°ÙB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide (LPS).
Reactivity
Human, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL36RN protein structure - BS60972 shown in red.