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- Antibody Data
- Antigen structure
- References [291]
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- Product number
- 15613-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15613-1-AP, RRID:AB_2105691
- Product name
- Fibronectin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Fibronectin antibody (Cat. #15613-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification.
Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum.
Doxorubicin promotes breast cancer cell migration and invasion via DCAF13.
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis.
Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo.
Ferulic Acid Ameliorates Hepatic Inflammation and Fibrotic Liver Injury by Inhibiting PTP1B Activity and Subsequent Promoting AMPK Phosphorylation.
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Binding of Plasminogen to Streptococcus suis Protein Endopeptidase O Facilitates Evasion of Innate Immunity in Streptococcus suis.
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling.
Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28.
Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys.
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/NFκb/FN1 Signaling.
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Exercise training ameliorates early diabetic kidney injury by regulating the H2 S/SIRT1/p53 pathway.
Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway.
MiR-192-5p inhibits proliferation, migration, and invasion in papillary thyroid carcinoma cells by regulation of SH3RF3.
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
KLF15 negatively regulates cardiac fibrosis by which SDF-1β attenuates cardiac fibrosis in type 2 diabetic mice.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
A novel in vitro assay for peripheral nerve-related cell migration that preserves both extracellular matrix-derived molecular cues and nanofiber-derived topography.
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis.
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.
Fibronectin-integrin signaling regulates PLVAP localization at endothelial fenestrae by microtubule stabilization.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Improved response of human gingival fibroblasts to titanium coated with micro-/nano-structured tantalum.
A HIF1A/miR-485-5p/SRPK1 axis modulates the aggressiveness of glioma cells upon hypoxia.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
pH-Sensitive Nanoparticles Composed Solely of Membrane-Disruptive Macromolecules for Treating Pancreatic Cancer.
The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction.
Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Long Noncoding RNA CTD-2589M5.4 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion Via Downregulation of the Extracellular Matrix-Receptor Interaction Pathway.
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics.
Comparison of Gene Expression Patterns in Articular Cartilage and Xiphoid Cartilage.
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Metformin attenuates post-epidural fibrosis by inhibiting the TGF-β1/Smad3 and HMGB1/TLR4 signaling pathways.
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
IL-33-induced neutrophil extracellular traps degrade fibronectin in a murine model of bronchopulmonary dysplasia.
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation.
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis.
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis.
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
Ischemia-reperfusion injury of brain induces endothelial-mesenchymal transition and vascular fibrosis via activating let-7i/TGF-βR1 double-negative feedback loop.
Cardamonin retards progression of autosomal dominant polycystic kidney disease via inhibiting renal cyst growth and interstitial fibrosis.
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
IRF-1 promotes renal fibrosis by downregulation of Klotho.
WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy.
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Monocyte-derived alveolar macrophage apolipoprotein E participates in pulmonary fibrosis resolution.
Antisense Oligonucleotide in LNA-Gapmer Design Targeting TGFBR2-A Key Single Gene Target for Safe and Effective Inhibition of TGFβ Signaling.
Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.
HMGB1 protein promotes glomerular mesangial matrix deposition via TLR2 in lupus nephritis.
RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.
Transcriptomic analysis of the mechanisms of alleviating renal interstitial fibrosis using the traditional Chinese medicine Kangxianling in a rat model.
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells.
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
LRIG3 represses cell motility by inhibiting slug via inactivating ERK signaling in human colorectal cancer.
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Type I collagen facilitates safe and reliable expansion of human dental pulp stem cells in xenogeneic serum-free culture.
Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signalling.
Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked NADPH oxidase 4 polyubiquitination and degradation.
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation.
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
miR-363-3p inhibits migration, invasion, and epithelial-mesenchymal transition by targeting NEDD9 and SOX4 in non-small-cell lung cancer.
Anti-Adhesive, Platelet Gathering Effects of c-RGD Modified Poly(p-dioxanone-co-l-Phe) Electrospun Membrane and Its Comprehensive Application in Intestinal Anastomosis.
A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury.
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved.
Stem-cell-derived ECM sheet-implant complexes for enhancing osseointegration.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis.
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake.
FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX.
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Presence and function of stress granules in atrial fibrillation.
Development and validation of a novel phonomimetic bioreactor.
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
FoxO1-mediated inhibition of STAT1 alleviates tubulointerstitial fibrosis and tubule apoptosis in diabetic kidney disease.
TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling.
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Rhodojaponin II attenuates kidney injury by regulating TGF-β1/Smad pathway in mice with adriamycin nephropathy.
NLRP3 inflammasome inhibition attenuates cisplatin-induced renal fibrosis by decreasing oxidative stress and inflammation.
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1.
Olfactory ensheathing cells facilitate neurite sprouting and outgrowth by secreting high levels of hevin.
HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression.
SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2.
MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice.
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.
Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice.
Three kinds of corneal host cells contribute differently to corneal neovascularization.
EZH2-DNMT1-mediated epigenetic silencing of miR-142-3p promotes metastasis through targeting ZEB2 in nasopharyngeal carcinoma.
RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.
Role of PM2.5 in the development and progression of COPD and its mechanisms.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Loss of TMEM126A promotes extracellular matrix remodeling, epithelial-to-mesenchymal transition, and breast cancer metastasis by regulating mitochondrial retrograde signaling.
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling.
Protein kinase C inhibitor chelerythrine attenuates partial unilateral ureteral obstruction induced kidney injury in neonatal rats.
An improved cellular enucleation method with extracellular matrix and colchicine facilitates the study of nucleocytoplasmic interaction.
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration.
Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.
MicroRNA-432 is downregulated in cervical cancer and directly targets FN1 to inhibit cell proliferation and invasion.
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
Kindlin-2 regulates hepatic stellate cells activation and liver fibrogenesis.
Cyclin G2 Suppresses Glomerulosclerosis by Regulating Canonical Wnt Signalling.
Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway.
LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1.
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis.
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loop.
The pro-metastasis effect of circANKS1B in breast cancer.
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Towards an in vitro fibrogenesis model of human vocal fold scarring.
Methanol fixed fibroblasts serve as feeder cells to maintain stem cells in the pluripotent state in vitro.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Fibronectin Facilitates Enterovirus 71 Infection by Mediating Viral Entry.
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice.
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Regulation of pancreatic stellate cell activation by Notch3.
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation.
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
RGC-32 regulates reactive astrocytosis and extracellular matrix deposition in experimental autoimmune encephalomyelitis.
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Saxagliptin Attenuates Albuminuria by Inhibiting Podocyte Epithelial- to-Mesenchymal Transition via SDF-1α in Diabetic Nephropathy.
The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis.
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
miR-206 inhibits FN1 expression and proliferation and promotes apoptosis of rat type II alveolar epithelial cells.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
TGFβ-incurred epigenetic aberrations of miRNA and DNA methyltransferase suppress Klotho and potentiate renal fibrosis.
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Autophagy plays a role in FSTL1-induced epithelial mesenchymal transition and airway remodeling in asthma.
Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease.
Phosphoinositide 3-kinase/protein kinase B/periostin mediated platelet-derived growth factor-induced cell proliferation and extracellular matrix production in lupus nephritis.
5-Aza-2'-deoxycytidine induces human Tenon's capsule fibroblasts differentiation and fibrosis by up-regulating TGF-β type I receptor.
MicroRNA-139 targets fibronectin 1 to inhibit papillary thyroid carcinoma progression.
Low molecular weight fucoidan and its fractions inhibit renal epithelial mesenchymal transition induced by TGF-β1 or FGF-2.
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice.
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation.
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy.
miR-26a suppresses EMT by disrupting the Lin28B/let-7d axis: potential cross-talks among miRNAs in IPF.
Silence of fibronectin 1 increases cisplatin sensitivity of non-small cell lung cancer cell line.
Glucocorticoid exposure in early placentation induces preeclampsia in rats via interfering trophoblast development.
Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling.
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis.
Pediatric Origins of Nephrolithiasis-Associated Atherosclerosis.
MiR-25 promotes hepatocellular carcinoma cell growth, migration and invasion by inhibiting RhoGDI1.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
IL-33 promotes airway remodeling and is a marker of asthma disease severity.
Benzalkonium chloride induces subconjunctival fibrosis through the COX-2-modulated activation of a TGF-β1/Smad3 signaling pathway.
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM.
Reduction of microRNA-206 contributes to the development of bronchopulmonary dysplasia through up-regulation of fibronectin 1.
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Global profiling of proteolytically modified proteins in human metastatic hepatocellular carcinoma cell lines reveals CAPN2 centered network.
Zhang X, Lai K, Li S, Wang J, Li J, Wang W, Ni S, Lu B, Grzybowski A, Ji J, Han H, Yao K
Bioactive materials 2022 Mar;9:343-357
Bioactive materials 2022 Mar;9:343-357
Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum.
Lu CL, Ortmeier S, Brudvig J, Moretti T, Cain J, Boyadjiev SA, Weimer JM, Kim J
Traffic (Copenhagen, Denmark) 2022 Jan;23(1):81-93
Traffic (Copenhagen, Denmark) 2022 Jan;23(1):81-93
Doxorubicin promotes breast cancer cell migration and invasion via DCAF13.
Sun Z, Zhou D, Yang J, Zhang D
FEBS open bio 2022 Jan;12(1):221-230
FEBS open bio 2022 Jan;12(1):221-230
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Tao H, Zhao H, Ge D, Liao J, Shao L, Mo A, Hu L, Xu K, Wu J, Mu M, Li B, Tao X, Wang J
Toxicology letters 2022 Feb 1;355:150-159
Toxicology letters 2022 Feb 1;355:150-159
Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis.
Li S, Jiang S, Zhang Q, Jin B, Lv D, Li W, Zhao M, Jiang C, Dai C, Liu Z
Frontiers in cell and developmental biology 2021;9:733831
Frontiers in cell and developmental biology 2021;9:733831
Tubular cell-derived exosomal miR-150-5p contributes to renal fibrosis following unilateral ischemia-reperfusion injury by activating fibroblast in vitro and in vivo.
Zhou X, Zhao S, Li W, Ruan Y, Yuan R, Ning J, Jiang K, Xie J, Yao X, Li H, Li C, Rao T, Yu W, Cheng F
International journal of biological sciences 2021;17(14):4021-4033
International journal of biological sciences 2021;17(14):4021-4033
Ferulic Acid Ameliorates Hepatic Inflammation and Fibrotic Liver Injury by Inhibiting PTP1B Activity and Subsequent Promoting AMPK Phosphorylation.
Wu J, Xue X, Fan G, Gu Y, Zhou F, Zheng Q, Liu R, Li Y, Ma B, Li S, Huang G, Ma L, Li X
Frontiers in pharmacology 2021;12:754976
Frontiers in pharmacology 2021;12:754976
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Yu HX, Lin W, Yang K, Wei LJ, Chen JL, Liu XY, Zhong K, Chen X, Pei M, Yang HT
Frontiers in pharmacology 2021;12:741801
Frontiers in pharmacology 2021;12:741801
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Han Y, Jiang M, He R, Lv X, Liao X, He Y, Zhang F, Long L, Jiang G, Peng Z, Tao L, Hu G, Meng J
Frontiers in pharmacology 2021;12:713572
Frontiers in pharmacology 2021;12:713572
Binding of Plasminogen to Streptococcus suis Protein Endopeptidase O Facilitates Evasion of Innate Immunity in Streptococcus suis.
Zhou Y, Yan K, Sun C, Liu F, Peng W, Chen H, Yuan F, Bei W, Li J
Frontiers in microbiology 2021;12:694103
Frontiers in microbiology 2021;12:694103
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Liu L, Li Q, Yin J, Zhao Z, Sun L, Ran Q, Du X, Wang Y, Li Y, Yang Q, Chen Y, Weng X, Cai W, Zhu X
Frontiers in pharmacology 2021;12:669730
Frontiers in pharmacology 2021;12:669730
Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling.
Wu F, Zhao Y, Shao Q, Fang K, Dong R, Jiang S, Lu F, Luo J, Chen G
Frontiers in pharmacology 2021;12:646331
Frontiers in pharmacology 2021;12:646331
Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28.
Chen B, Sang Y, Song X, Zhang D, Wang L, Zhao W, Liang Y, Zhang N, Yang Q
Theranostics 2021;11(8):3932-3947
Theranostics 2021;11(8):3932-3947
Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys.
Zhao S, Li W, Yu W, Rao T, Li H, Ruan Y, Yuan R, Li C, Ning J, Li S, Chen W, Cheng F, Zhou X
Theranostics 2021;11(18):8660-8673
Theranostics 2021;11(18):8660-8673
Local administration of liposomal-based Srpx2 gene therapy reverses pulmonary fibrosis by blockading fibroblast-to-myofibroblast transition.
Wang Q, Liu J, Hu Y, Pan T, Xu Y, Yu J, Xiong W, Zhou Q, Wang Y
Theranostics 2021;11(14):7110-7125
Theranostics 2021;11(14):7110-7125
The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/NFκb/FN1 Signaling.
Sun W, Qin Y, Wang Z, Dong W, He L, Zhang T, Zhang H
Frontiers in oncology 2021;11:610547
Frontiers in oncology 2021;11:610547
miR-23a-3p regulates the inflammatory response and fibrosis in diabetic kidney disease by targeting early growth response 1.
Sheng S, Zou M, Yang Y, Guan M, Ren S, Wang X, Wang L, Xue Y
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
In vitro cellular & developmental biology. Animal 2021 Sep;57(8):763-774
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Tsai WC, Yu TY, Chang GJ, Chang HN, Lin LP, Lin MS, Pang JS
The American journal of sports medicine 2021 Sep;49(11):3102-3112
The American journal of sports medicine 2021 Sep;49(11):3102-3112
Exercise training ameliorates early diabetic kidney injury by regulating the H2 S/SIRT1/p53 pathway.
Yang L, Li DX, Cao BQ, Liu SJ, Xu DH, Zhu XY, Liu YJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway.
Li S, Gan L, Tian YJ, Tian Y, Fan RZ, Huang D, Yuan FY, Zhang X, Lin Y, Zhu QF, Tang GH, Yan XL, Yin S
Bioorganic chemistry 2021 Sep;114:105222
Bioorganic chemistry 2021 Sep;114:105222
MiR-192-5p inhibits proliferation, migration, and invasion in papillary thyroid carcinoma cells by regulation of SH3RF3.
Fu S, Ma C, Tang X, Ma X, Jing G, Zhao N, Ran J
Bioscience reports 2021 Sep 30;41(9)
Bioscience reports 2021 Sep 30;41(9)
A rapid and simple procedure for the isolation and cultivation of fibroblast-like cells from medaka and zebrafish embryos and fin clip biopsies.
Beedgen L, Hüllen A, Gücüm S, Thumberger T, Wittbrodt J, Thiel C
Laboratory animals 2021 Sep 22;:236772211045483
Laboratory animals 2021 Sep 22;:236772211045483
KLF15 negatively regulates cardiac fibrosis by which SDF-1β attenuates cardiac fibrosis in type 2 diabetic mice.
Tian Y, Wang Z, Zheng X, Song W, Cai L, Rane M, Zhao Y
Toxicology and applied pharmacology 2021 Sep 15;427:115654
Toxicology and applied pharmacology 2021 Sep 15;427:115654
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
A novel in vitro assay for peripheral nerve-related cell migration that preserves both extracellular matrix-derived molecular cues and nanofiber-derived topography.
Achenbach P, Hambeukers I, Pierling AL, Gerardo-Nava JL, Hillerbrand L, Sechi AS, Glücks KJ, Dalton PD, Pich A, Dievernich A, Altinova H, Brook GA
Journal of neuroscience methods 2021 Sep 1;361:109289
Journal of neuroscience methods 2021 Sep 1;361:109289
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis.
Deng YJ, Lin XP, Li XQ, Lu PF, Cai Y, Liu LL, Pei GC, Han M
Current medical science 2021 Oct;41(5):880-887
Current medical science 2021 Oct;41(5):880-887
The long non-coding RNA PFI protects against pulmonary fibrosis by interacting with splicing regulator SRSF1.
Sun J, Jin T, Su W, Guo Y, Niu Z, Guo J, Li L, Wang J, Ma L, Yu T, Li X, Zhou Y, Shan H, Liang H
Cell death and differentiation 2021 Oct;28(10):2916-2930
Cell death and differentiation 2021 Oct;28(10):2916-2930
Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.
Xia W, Xie J, Cai Z, Liu X, Wen J, Cui ZK, Zhao R, Zhou X, Chen J, Mao X, Gu Z, Zou Z, Zou Z, Zhang Y, Zhao M, Mac M, Song Q, Bai X
Nature communications 2021 Oct 15;12(1):6043
Nature communications 2021 Oct 15;12(1):6043
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Yang M, Wang D, Gan S, Wang B, Yu L, Xie Y, Fan L, Ma J, Chen W
The Science of the total environment 2021 Oct 10;790:148041
The Science of the total environment 2021 Oct 10;790:148041
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
Lou P, Liu S, Wang Y, Pan C, Xu X, Zhao M, Liao G, Yang G, Yuan Y, Li L, Zhang J, Chen Y, Cheng J, Lu Y, Liu J
Acta biomaterialia 2021 Nov;135:100-112
Acta biomaterialia 2021 Nov;135:100-112
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis.
Xue X, Wu J, Ding M, Gao F, Zhou F, Xu B, Lu M, Li J, Li X
Chinese medicine 2021 Nov 4;16(1):112
Chinese medicine 2021 Nov 4;16(1):112
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Qin MY, Huang SQ, Zou XQ, Zhong XB, Yang YF, Zhang YT, Mi ZC, Zhang YS, Huang ZG
Journal of ethnopharmacology 2021 Nov 15;280:114414
Journal of ethnopharmacology 2021 Nov 15;280:114414
MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.
Liao W, Fan L, Li M, Deng H, Yang A, Liu F
Cell biology international 2021 May;45(5):948-956
Cell biology international 2021 May;45(5):948-956
Fibronectin-integrin signaling regulates PLVAP localization at endothelial fenestrae by microtubule stabilization.
Nakakura T, Suzuki T, Horiguchi K, Tanaka H, Arisawa K, Miyashita T, Nekooki-Machida Y, Hagiwara H
Cell and tissue research 2021 May;384(2):449-463
Cell and tissue research 2021 May;384(2):449-463
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Improved response of human gingival fibroblasts to titanium coated with micro-/nano-structured tantalum.
Zhang CN, Zhou LY, Qian SJ, Gu YX, Shi JY, Lai HC
International journal of implant dentistry 2021 May 3;7(1):36
International journal of implant dentistry 2021 May 3;7(1):36
A HIF1A/miR-485-5p/SRPK1 axis modulates the aggressiveness of glioma cells upon hypoxia.
Cheng L, Peng R, Guo P, Zhang H, Liu D, Liao X, Liu Y, Mo X, Liao Y
Experimental cell research 2021 May 1;402(1):112547
Experimental cell research 2021 May 1;402(1):112547
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
miR‑106b‑5p targeting SIX1 inhibits TGF‑β1‑induced pulmonary fibrosis and epithelial‑mesenchymal transition in asthma through regulation of E2F1.
Liu S, Chen X, Zhang S, Wang X, Du X, Chen J, Zhou G
International journal of molecular medicine 2021 Mar;47(3)
International journal of molecular medicine 2021 Mar;47(3)
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Xu D, Chen PP, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
pH-Sensitive Nanoparticles Composed Solely of Membrane-Disruptive Macromolecules for Treating Pancreatic Cancer.
Fan F, Jin L, Yang L
ACS applied materials & interfaces 2021 Mar 24;13(11):12824-12835
ACS applied materials & interfaces 2021 Mar 24;13(11):12824-12835
The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity.
Chen S, Liu X, Peng C, Tan C, Sun H, Liu H, Zhang Y, Wu P, Cui C, Liu C, Yang D, Li Z, Lu J, Guan J, Ke X, Wang R, Bo X, Xu X, Han J, Liu J
Cell metabolism 2021 Mar 2;33(3):565-580.e7
Cell metabolism 2021 Mar 2;33(3):565-580.e7
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Regulation of connective tissue growth factor expression by miR-133b for the treatment of renal interstitial fibrosis in aged mice with unilateral ureteral obstruction.
Cao D, Wang Y, Zhang Y, Zhang Y, Huang Q, Yin Z, Cai G, Chen X, Sun X
Stem cell research & therapy 2021 Mar 10;12(1):171
Stem cell research & therapy 2021 Mar 10;12(1):171
Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.
Chen X, Li C, Liu J, He Y, Wei Y, Chen J
International immunopharmacology 2021 Jun;95:107519
International immunopharmacology 2021 Jun;95:107519
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Sun XH, Xiao HM, Zhang M, Lin ZY, Yang Y, Chen R, Liu PQ, Huang KP, Huang HQ
Biochemical pharmacology 2021 Jun;188:114562
Biochemical pharmacology 2021 Jun;188:114562
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
Yang X, Bao M, Fang Y, Yu X, Ji J, Ding X
Journal of translational medicine 2021 Jun 30;19(1):283
Journal of translational medicine 2021 Jun 30;19(1):283
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W
Journal of cellular and molecular medicine 2021 Jun 2;
Journal of cellular and molecular medicine 2021 Jun 2;
A Novel Rat Model with Long Range Optic Nerve Injury to Study Retinal Ganglion Cells Endogenous Regeneration.
Zhang S, Liu B, Zhu H, Jin H, Gong Z, Qiu H, Xu M, Chen M, Nan K, Wu W
Neuroscience 2021 Jun 15;465:71-84
Neuroscience 2021 Jun 15;465:71-84
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation.
Chen T, Guo Y, Wang J, Ai L, Ma L, He W, Li Z, Yu X, Li J, Fan X, Gu Y, Liang H
Cell death & disease 2021 Jun 10;12(6):600
Cell death & disease 2021 Jun 10;12(6):600
Long Noncoding RNA CTD-2589M5.4 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion Via Downregulation of the Extracellular Matrix-Receptor Interaction Pathway.
Gu Y, Huang K, Zhang M, Teng F, Ge L, Zhou J, Xu J, Jia X
Cancer biotherapy & radiopharmaceuticals 2021 Jul 8;
Cancer biotherapy & radiopharmaceuticals 2021 Jul 8;
Pterostilbene alleviates pulmonary fibrosis by regulating ASIC2.
Peng Y, Zhang Y, Zhang Y, Wang X, Xia Y
Chinese medicine 2021 Jul 28;16(1):66
Chinese medicine 2021 Jul 28;16(1):66
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma.
Wang W, Sun R, Zeng L, Chen Y, Zhang N, Cao S, Deng S, Meng X, Yang S
Life sciences 2021 Jul 1;276:119439
Life sciences 2021 Jul 1;276:119439
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer.
Bin J, Nie S, Tang Z, Kang A, Fu Z, Hu Y, Liao Q, Xiong W, Zhou Y, Tang Y, Jiang J
Journal of cellular physiology 2021 Jan;236(1):523-535
Journal of cellular physiology 2021 Jan;236(1):523-535
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats.
Zhang C, Lu W, Luo X, Liu S, Li Y, Zheng Q, Liu W, Wu X, Chen Y, Jiang Q, Zhang Z, Gu G, Chen J, Chen H, Liao J, Liu C, Hong C, Tang H, Sun D, Yang K, Wang J
British journal of pharmacology 2021 Jan;178(1):217-235
British journal of pharmacology 2021 Jan;178(1):217-235
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Anti-renal interstitial fibrosis effect of norcantharidin is exerted through inhibition of PP2Ac-mediated C-terminal phosphorylation of Smad3.
Luo HW, Yin DD, Xiao Z, Wen L, Liao YJ, Tang CY, Zeng D, Xiao HT, Li Y
Chemical biology & drug design 2021 Feb;97(2):293-304
Chemical biology & drug design 2021 Feb;97(2):293-304
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Wu L, Wang Q, Guo F, Ma X, Wang J, Zhao Y, Yan Y, Qin G
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Cui Y, Wang Y, Liu G
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Wu Y, Qi Y, Qiu Z, Chen W
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Wang X, Wan W, Lu J, Quan G, Pan X, Liu P
International journal of pharmaceutics 2021 Dec 15;610:121223
International journal of pharmaceutics 2021 Dec 15;610:121223
Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.
Peng YF, Lin H, Liu DC, Zhu XY, Huang N, Wei YX, Li L
Cellular signalling 2021 Aug;84:110001
Cellular signalling 2021 Aug;84:110001
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Peng C, Wang Y, Ji L, Kuang L, Yu Z, Li H, Zhang J, Zhao J
Current eye research 2021 Aug;46(8):1137-1147
Current eye research 2021 Aug;46(8):1137-1147
IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics.
Zhang S, Fan Y, Qin L, Fang X, Zhang C, Yue J, Bai W, Wang G, Chen Z, Renz H, Skevaki C, Liu X, Xie M
Respiratory research 2021 Aug 3;22(1):216
Respiratory research 2021 Aug 3;22(1):216
Comparison of Gene Expression Patterns in Articular Cartilage and Xiphoid Cartilage.
Yao B, Zhou Z, Zhang M, Leng X, Zhao D
Biochemical genetics 2021 Aug 19;
Biochemical genetics 2021 Aug 19;
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Zhou Z, Gao Z, Yan W, Zhang Y, Huang J, Xiong K
Annals of translational medicine 2021 Apr;9(7):526
Annals of translational medicine 2021 Apr;9(7):526
Metformin attenuates post-epidural fibrosis by inhibiting the TGF-β1/Smad3 and HMGB1/TLR4 signaling pathways.
Song Z, Wu T, Sun J, Wang H, Hua F, Nicolas YSM, Kc R, Chen K, Jin Z, Liu J, Zhang M
Journal of cellular and molecular medicine 2021 Apr;25(7):3272-3283
Journal of cellular and molecular medicine 2021 Apr;25(7):3272-3283
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
Han C, Jiang YH, Li W, Liu Y
Journal of ethnopharmacology 2021 Apr 6;269:113768
Journal of ethnopharmacology 2021 Apr 6;269:113768
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Lin T, Tao J, Chen Y, Zhang Y, Li F, Zhang Y, Han X, Zhao Z, Liu G, Li H
Biological trace element research 2021 Apr 24;
Biological trace element research 2021 Apr 24;
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52
Cell death discovery 2020;6:52
IL-33-induced neutrophil extracellular traps degrade fibronectin in a murine model of bronchopulmonary dysplasia.
Jin R, Xu J, Gao Q, Mao X, Yin J, Lu K, Guo Y, Zhang M, Cheng R
Cell death discovery 2020;6:33
Cell death discovery 2020;6:33
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation.
Zhang Y, Tao C, Xuan C, Jiang J, Cao W
Oxidative medicine and cellular longevity 2020;2020:9542165
Oxidative medicine and cellular longevity 2020;2020:9542165
Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model.
Yang K, Fan B, Zhao Q, Ji Y, Liu P, Gao S, Ren T, Dou Y, Pei M, Yang H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7291075
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Gu J, Chen C, Wang J, Chen T, Yao W, Yan T, Liu Z
Oxidative medicine and cellular longevity 2020;2020:2452848
Oxidative medicine and cellular longevity 2020;2020:2452848
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Melatonin ameliorates hyperglycaemia-induced renal inflammation by inhibiting the activation of TLR4 and TGF-β1/Smad3 signalling pathway.
Wei J, Wang Y, Qi X, Fan Z, Wu Y
American journal of translational research 2020;12(5):1584-1599
American journal of translational research 2020;12(5):1584-1599
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Huang J, Tong X, Zhang L, Zhang Y, Wang L, Wang D, Zhang S, Fan H
Frontiers in pharmacology 2020;11:550955
Frontiers in pharmacology 2020;11:550955
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis.
Sun Z, Ji N, Ma Q, Zhu R, Chen Z, Wang Z, Qian Y, Wu C, Hu F, Huang M, Zhang M
Frontiers in immunology 2020;11:1598
Frontiers in immunology 2020;11:1598
Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells.
Li J, Liu J, Yue W, Xu K, Cai W, Cui F, Li Z, Wang W, He J
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Journal of cellular and molecular medicine 2020 Sep;24(18):10501-10511
Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells.
Liao X, Li Y, Liu J, Zhang Y, Tan J, Kass DJ, Rojas M, Mallampalli RK, Zhao J, Zhao Y
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
Translational research : the journal of laboratory and clinical medicine 2020 Sep;223:15-24
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.
Qian W, Li Q, Wu X, Li W, Li Q, Zhang J, Li M, Zhang D, Zhao H, Zou X, Jia H, Zhang L, Yang XD, Hou Z
Oncogene 2020 Oct;39(44):6802-6815
Oncogene 2020 Oct;39(44):6802-6815
Neutrophil extracellular traps promote scar formation in post-epidural fibrosis.
Jin Z, Sun J, Song Z, Chen K, Nicolas YSM, Kc R, Ma Q, Liu J, Zhang M
NPJ Regenerative medicine 2020 Oct 30;5(1):19
NPJ Regenerative medicine 2020 Oct 30;5(1):19
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
Ye C, Xiong W, Lei CT, Tang H, Su H, Yi F, Zhang C
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Yuan Q, Xu T, Chen Y, Qu W, Sun D, Liu X, Sun L
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1436-1446
Sox13 promotes hepatocellular carcinoma metastasis by transcriptionally activating Twist1.
Feng M, Fang F, Fang T, Jiao H, You S, Wang X, Zhao W
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
Laboratory investigation; a journal of technical methods and pathology 2020 Nov;100(11):1400-1410
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hall-Roberts H, Agarwal D, Obst J, Smith TB, Monzón-Sandoval J, Di Daniel E, Webber C, James WS, Mead E, Davis JB, Cowley SA
Alzheimer's research & therapy 2020 Nov 16;12(1):151
Alzheimer's research & therapy 2020 Nov 16;12(1):151
Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation.
Zeng D, Xiao Z, Xu Q, Luo H, Wen L, Tang C, Shan Y, Tian J, Wei J, Li Y
Life sciences 2020 Nov 1;260:118488
Life sciences 2020 Nov 1;260:118488
Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways.
Geng XQ, Ma A, He JZ, Wang L, Jia YL, Shao GY, Li M, Zhou H, Lin SQ, Ran JH, Yang BX
Acta pharmacologica Sinica 2020 May;41(5):670-677
Acta pharmacologica Sinica 2020 May;41(5):670-677
Ischemia-reperfusion injury of brain induces endothelial-mesenchymal transition and vascular fibrosis via activating let-7i/TGF-βR1 double-negative feedback loop.
Chen D, Li L, Wang Y, Xu R, Peng S, Zhou L, Deng Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):7178-7191
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):7178-7191
Cardamonin retards progression of autosomal dominant polycystic kidney disease via inhibiting renal cyst growth and interstitial fibrosis.
He J, Zhou H, Meng J, Zhang S, Li X, Wang S, Shao G, Jin W, Geng X, Zhu S, Yang B
Pharmacological research 2020 May;155:104751
Pharmacological research 2020 May;155:104751
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis.
Ma J, Xu Y, Li W, Zhou Y, Wang D, Yang M, Wang B, Chen W
Toxicology letters 2020 May 17;330:134-143
Toxicology letters 2020 May 17;330:134-143
IRF-1 promotes renal fibrosis by downregulation of Klotho.
Li Y, Liu Y, Huang Y, Yang K, Xiao T, Xiong J, Wang K, Liu C, He T, Yu Y, Han W, Wang Y, Bi X, Zhang J, Huang Y, Zhang B, Zhao J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4415-4429
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4415-4429
WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy.
Yang X, Wang H, Tu Y, Li Y, Zou Y, Li G, Wang L, Zhong X
Journal of cellular physiology 2020 Mar;235(3):2009-2022
Journal of cellular physiology 2020 Mar;235(3):2009-2022
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Liang H, Yu M, Yang R, Zhang L, Zhang L, Zhu D, Luo H, Hong Y, Yu T, Sun J, Shan H, Gu Y
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Hu Y, Yu J, Wang Q, Zhang L, Chen X, Cao Y, Zhao J, Xu Y, Jiang D, Wang Y, Xiong W
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Monocyte-derived alveolar macrophage apolipoprotein E participates in pulmonary fibrosis resolution.
Cui H, Jiang D, Banerjee S, Xie N, Kulkarni T, Liu RM, Duncan SR, Liu G
JCI insight 2020 Mar 12;5(5)
JCI insight 2020 Mar 12;5(5)
Antisense Oligonucleotide in LNA-Gapmer Design Targeting TGFBR2-A Key Single Gene Target for Safe and Effective Inhibition of TGFβ Signaling.
Kuespert S, Heydn R, Peters S, Wirkert E, Meyer AL, Siebörger M, Johannesen S, Aigner L, Bogdahn U, Bruun TH
International journal of molecular sciences 2020 Mar 12;21(6)
International journal of molecular sciences 2020 Mar 12;21(6)
Long non-coding RNA DBH-AS1 promotes cancer progression in diffuse large B-cell lymphoma by targeting FN1 via RNA-binding protein BUD13.
Song Y, Gao F, Peng Y, Yang X
Cell biology international 2020 Jun;44(6):1331-1340
Cell biology international 2020 Jun;44(6):1331-1340
HMGB1 protein promotes glomerular mesangial matrix deposition via TLR2 in lupus nephritis.
Feng X, Yang R, Tian Y, Miao X, Guo H, Gao F, Yang L, Zhao S, Zhang W, Liu J, Li H, Tian Y, Zhao L, Wang S, Liu W, Wang K, Li Y, Wang Z, Liu Q, Wang C, Liu S
Journal of cellular physiology 2020 Jun;235(6):5111-5119
Journal of cellular physiology 2020 Jun;235(6):5111-5119
RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.
Sundararaman A, Fukushima Y, Norman JC, Uemura A, Mellor H
Current biology : CB 2020 Jun 8;30(11):2146-2155.e5
Current biology : CB 2020 Jun 8;30(11):2146-2155.e5
Transcriptomic analysis of the mechanisms of alleviating renal interstitial fibrosis using the traditional Chinese medicine Kangxianling in a rat model.
Jiang Y, Zhu Y, Zhen T, Li J, Xing K, He L, Zhu S
Scientific reports 2020 Jun 30;10(1):10682
Scientific reports 2020 Jun 30;10(1):10682
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells.
Li Y, Liu Y, Wang K, Huang Y, Han W, Xiong J, Yang K, Liu M, Xiao T, Liu C, He T, Bi X, Zhang J, Zhang B, Zhao J
BMC molecular and cell biology 2020 Jun 22;21(1):45
BMC molecular and cell biology 2020 Jun 22;21(1):45
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Deng M, Tan J, Hu C, Hou T, Peng W, Liu J, Yu B, Dai Q, Zhou J, Yang Y, Dong R, Ruan C, Dong S, Xu J
Advanced healthcare materials 2020 Jul;9(13):e2000353
Advanced healthcare materials 2020 Jul;9(13):e2000353
LRIG3 represses cell motility by inhibiting slug via inactivating ERK signaling in human colorectal cancer.
Zeng K, Chen X, Xu M, Liu X, Li C, Xu X, Pan B, Qin J, He B, Pan Y, Huiling S, Xu T, Wang S
IUBMB life 2020 Jul;72(7):1393-1403
IUBMB life 2020 Jul;72(7):1393-1403
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Sun X, Huang K, Haiming X, Lin Z, Yang Y, Zhang M, Liu P, Huang H
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Type I collagen facilitates safe and reliable expansion of human dental pulp stem cells in xenogeneic serum-free culture.
Mochizuki M, Sagara H, Nakahara T
Stem cell research & therapy 2020 Jul 14;11(1):267
Stem cell research & therapy 2020 Jul 14;11(1):267
Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption.
Cui D, Liu S, Tang M, Lu Y, Zhao M, Mao R, Wang C, Yuan Y, Li L, Chen Y, Cheng J, Lu Y, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153111
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jan;66:153111
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Su H, Ye C, Lei CT, Tang H, Zeng JY, Yi F, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway.
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, Xu J, Li D, Yao H, Liu W, Deng B, Lu W
Redox biology 2020 Jan;28:101356
Redox biology 2020 Jan;28:101356
Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signalling.
Wang Y, Li C, Gu J, Chen C, Duanmu J, Miao J, Yao W, Tao J, Tu M, Xiong B, Zhao L, Liu Z
Journal of cellular and molecular medicine 2020 Jan;24(1):941-953
Journal of cellular and molecular medicine 2020 Jan;24(1):941-953
Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked NADPH oxidase 4 polyubiquitination and degradation.
Chen Z, Sun X, Chen Q, Lan T, Huang K, Xiao H, Lin Z, Yang Y, Liu P, Huang H
British journal of pharmacology 2020 Jan;177(1):145-160
British journal of pharmacology 2020 Jan;177(1):145-160
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, Zhang M, Liu P, Quan S, Huang H
Pharmacological research 2020 Jan;151:104559
Pharmacological research 2020 Jan;151:104559
Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation.
Ouyang F, Liu X, Liu G, Qiu H, He Y, Hu H, Jiang P
Aging 2020 Jan 8;12(1):996-1010
Aging 2020 Jan 8;12(1):996-1010
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, Xu G
Chemico-biological interactions 2020 Jan 25;316:108926
Chemico-biological interactions 2020 Jan 25;316:108926
miR-485 suppresses inflammation and proliferation of mesangial cells in an in vitro model of diabetic nephropathy by targeting NOX5.
Wu J, Lu K, Zhu M, Xie X, Ding Y, Shao X, Chen Y, Liu J, Xu M, Xu Y, Zhou J, Shen X, Zhu C
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Biochemical and biophysical research communications 2020 Jan 22;521(4):984-990
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
Gersch RP, Raum JC, Calvert C, Percec I
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
miR-363-3p inhibits migration, invasion, and epithelial-mesenchymal transition by targeting NEDD9 and SOX4 in non-small-cell lung cancer.
Chang J, Gao F, Chu H, Lou L, Wang H, Chen Y
Journal of cellular physiology 2020 Feb;235(2):1808-1820
Journal of cellular physiology 2020 Feb;235(2):1808-1820
Anti-Adhesive, Platelet Gathering Effects of c-RGD Modified Poly(p-dioxanone-co-l-Phe) Electrospun Membrane and Its Comprehensive Application in Intestinal Anastomosis.
Wang B, Feng C, Dang J, Niu L, Shen C, Yang X, Zhang T, Zhang X
Macromolecular bioscience 2020 Feb;20(2):e1900344
Macromolecular bioscience 2020 Feb;20(2):e1900344
A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury.
Liu S, Zhao M, Zhou Y, Li L, Wang C, Yuan Y, Li L, Liao G, Bresette W, Chen Y, Cheng J, Lu Y, Liu J
Acta biomaterialia 2020 Feb;103:102-114
Acta biomaterialia 2020 Feb;103:102-114
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
Yang X, Yan H, Jiang N, Yu Z, Yuan J, Ni Z, Fang W
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Chen ZQ, Sun XH, Li XJ, Xu ZC, Yang Y, Lin ZY, Xiao HM, Zhang M, Quan SJ, Huang HQ
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved.
Shin SJ, Chen CH, Kuo WC, Chan HC, Chan HC, Lin KD, Ke LY
Metabolism: clinical and experimental 2020 Dec;113:154403
Metabolism: clinical and experimental 2020 Dec;113:154403
Stem-cell-derived ECM sheet-implant complexes for enhancing osseointegration.
Feng Y, Jiang Z, Zhang Y, Miao X, Yu Q, Xie Z, Yang G
Biomaterials science 2020 Dec 7;8(23):6647-6656
Biomaterials science 2020 Dec 7;8(23):6647-6656
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis.
Yao W, Yang P, Qi Y, Jin L, Zhao A, Ding M, Wang D, Li Y, Hao C
The Science of the total environment 2020 Dec 10;747:141531
The Science of the total environment 2020 Dec 10;747:141531
Metformin inhibits extracellular matrix accumulation, inflammation and proliferation of mesangial cells in diabetic nephropathy by regulating H19/miR-143-3p/TGF-β1 axis.
Xu J, Xiang P, Liu L, Sun J, Ye S
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
The Journal of pharmacy and pharmacology 2020 Aug;72(8):1101-1109
Melatonin Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad3 Pathways in db/db Diabetic Mice.
Fan Z, Qi X, Yang W, Xia L, Wu Y
Archives of medical research 2020 Aug;51(6):524-534
Archives of medical research 2020 Aug;51(6):524-534
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
Jin M, Gao D, Wang R, Sik A, Liu K
Oncology reports 2020 Aug;44(2):555-564
Oncology reports 2020 Aug;44(2):555-564
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Xu B, Wang C, Wang YL, Chen SQ, Wu JP, Zhu WD, Wang CY, Guan H, Guan C, You ZH, Chen M
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
Tseng WC, Tsai MT, Chen NJ, Tarng DC
International journal of molecular sciences 2020 Aug 19;21(17)
International journal of molecular sciences 2020 Aug 19;21(17)
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J, Lu L
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
Ma T, Liang Y, Li Y, Song X, Zhang N, Li X, Chen B, Zhao W, Wang L, Yang Q
Cellular signalling 2020 Apr;68:109536
Cellular signalling 2020 Apr;68:109536
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580
Journal of ethnopharmacology 2020 Apr 24;252:112580
MicroRNA-183 regulates lipopolysaccharide-induced oxidative stress of hippocampal neurons by targeting the fibronectin 1 gene.
Xie Q, Feng L, Zhang C, Gan L
Neuroscience letters 2020 Apr 23;725:134902
Neuroscience letters 2020 Apr 23;725:134902
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake.
Wang G, Li Q, Chen D, Wu B, Wu Y, Tong W, Huang P
Theranostics 2019;9(21):6191-6208
Theranostics 2019;9(21):6191-6208
FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX.
Ji L, Wang Q, Huang F, An T, Guo F, Zhao Y, Liu Y, He Y, Song Y, Qin G
Oxidative medicine and cellular longevity 2019;2019:3286928
Oxidative medicine and cellular longevity 2019;2019:3286928
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.
Rao N, Wang X, Xie J, Li J, Zhai Y, Li X, Fang T, Wang Y, Zhao Y, Ge L
Stem cells international 2019;2019:2751475
Stem cells international 2019;2019:2751475
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Li X, Li C, Zhu G, Yuan W, Xiao ZA
International archives of allergy and immunology 2019;179(4):304-319
International archives of allergy and immunology 2019;179(4):304-319
Presence and function of stress granules in atrial fibrillation.
Dong G, Liang F, Sun B, Wang C, Liu Y, Guan X, Yang B, Xiu C, Yang N, Liu F, Lu T, Han W
PloS one 2019;14(4):e0213769
PloS one 2019;14(4):e0213769
Development and validation of a novel phonomimetic bioreactor.
Kirsch A, Hortobagyi D, Stachl T, Karbiener M, Grossmann T, Gerstenberger C, Gugatschka M
PloS one 2019;14(3):e0213788
PloS one 2019;14(3):e0213788
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Li H, Cui X, Hu Q, Chen X, Zhou P
OncoTargets and therapy 2019;12:9201-9213
OncoTargets and therapy 2019;12:9201-9213
Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.
Ma TK, Xu L, Lu LX, Cao X, Li X, Li LL, Wang X, Fan QL
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2597-2608
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2597-2608
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Zhang C, Zhu X, Li L, Ma T, Shi M, Yang Y, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway.
Wang L, Zhang P, Li X, Zhang Y, Zhan Q, Wang C
American journal of translational research 2019;11(4):2590-2602
American journal of translational research 2019;11(4):2590-2602
Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling.
Huang F, Zhao Y, Wang Q, Hillebrands JL, van den Born J, Ji L, An T, Qin G
Frontiers in endocrinology 2019;10:441
Frontiers in endocrinology 2019;10:441
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Lou LL, Ni FQ, Chen L, Shaker S, Li W, Wang R, Tang GH, Yin S
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Sun L, Xu T, Chen Y, Qu W, Sun D, Song X, Yuan Q, Yao L
Life sciences 2019 Sep 1;232:116609
Life sciences 2019 Sep 1;232:116609
Potential role of M2 macrophage polarization in ventilator-induced lung fibrosis.
Wang L, Zhang Y, Zhang N, Xia J, Zhan Q, Wang C
International immunopharmacology 2019 Oct;75:105795
International immunopharmacology 2019 Oct;75:105795
FoxO1-mediated inhibition of STAT1 alleviates tubulointerstitial fibrosis and tubule apoptosis in diabetic kidney disease.
Huang F, Wang Q, Guo F, Zhao Y, Ji L, An T, Song Y, Liu Y, He Y, Qin G
EBioMedicine 2019 Oct;48:491-504
EBioMedicine 2019 Oct;48:491-504
TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling.
Wu X, Li S, Wang K, Hua W, Li S, Song Y, Zhang Y, Yang S, Yang C
Inflammation 2019 Oct;42(5):1575-1584
Inflammation 2019 Oct;42(5):1575-1584
RNA-Seq analysis of potential lncRNAs and genes for the anti-renal fibrotic effect of norcantharidin.
Xiao H, Liao Y, Tang C, Xiao Z, Luo H, Li J, Liu H, Sun L, Zeng D, Li Y
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Journal of cellular biochemistry 2019 Oct;120(10):17354-17367
Rhodojaponin II attenuates kidney injury by regulating TGF-β1/Smad pathway in mice with adriamycin nephropathy.
Qiu Y, Zhou J, Zhang H, Zhou H, Tang H, Lei C, Ye C, You C, Chen Y, Wang Y, Xiong J, Su H, Yao G, Zhang C
Journal of ethnopharmacology 2019 Oct 28;243:112078
Journal of ethnopharmacology 2019 Oct 28;243:112078
NLRP3 inflammasome inhibition attenuates cisplatin-induced renal fibrosis by decreasing oxidative stress and inflammation.
Li S, Lin Q, Shao X, Mou S, Gu L, Wang L, Zhang Z, Shen J, Zhou Y, Qi C, Jin H, Pang H, Ni Z
Experimental cell research 2019 Oct 1;383(1):111488
Experimental cell research 2019 Oct 1;383(1):111488
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.
Li W, Xie L, Ma J, Yang M, Wang B, Xu Y, Fan L, Mu G, Shi T, Chen W
Toxicology letters 2019 Oct 1;313:178-187
Toxicology letters 2019 Oct 1;313:178-187
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
Tan X, Hu L, Shu Z, Chen L, Li X, Du M, Sun D, Mao X, Deng S, Huang K, Zhang F
Diabetes 2019 Nov;68(11):2063-2073
Diabetes 2019 Nov;68(11):2063-2073
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Hu Y, Zheng Y, Dai M, Wang X, Wu J, Yu B, Zhang H, Cui Y, Kong W, Wu H, Yu X
Cancer science 2019 Nov;110(11):3442-3452
Cancer science 2019 Nov;110(11):3442-3452
ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1.
Zhou Y, Zhou Y, Wang K, Li T, Zhang M, Yang Y, Wang R, Hu R
Cancers 2019 Nov 27;11(12)
Cancers 2019 Nov 27;11(12)
Olfactory ensheathing cells facilitate neurite sprouting and outgrowth by secreting high levels of hevin.
Ge L, Zhuo Y, Wu P, Liu Y, Qi L, Teng X, Duan D, Chen P, Lu M
Journal of chemical neuroanatomy 2019 Nov 26;104:101728
Journal of chemical neuroanatomy 2019 Nov 26;104:101728
HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression.
Du X, Xu Q, Pan D, Xu D, Niu B, Hong W, Zhang R, Li X, Chen S
Cell death & disease 2019 Nov 18;10(12):873
Cell death & disease 2019 Nov 18;10(12):873
SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2.
Zhang N, Zhang H, Liu Y, Su P, Zhang J, Wang X, Sun M, Chen B, Zhao W, Wang L, Wang H, Moran MS, Haffty BG, Yang Q
Cell death and differentiation 2019 May;26(5):843-859
Cell death and differentiation 2019 May;26(5):843-859
MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
Liu Y, Bi X, Xiong J, Han W, Xiao T, Xu X, Yang K, Liu C, Jiang W, He T, Yu Y, Li Y, Zhang J, Zhang B, Zhao J
Molecular therapy : the journal of the American Society of Gene Therapy 2019 May 8;27(5):1051-1065
Molecular therapy : the journal of the American Society of Gene Therapy 2019 May 8;27(5):1051-1065
Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice.
Hwang SD, Song JH, Kim Y, Lim JH, Kim MY, Kim EN, Hong YA, Chung S, Choi BS, Kim YS, Park CW
Cell death & disease 2019 Mar 4;10(3):219
Cell death & disease 2019 Mar 4;10(3):219
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.
Ishiguro H, Kaito T, Yarimitsu S, Hashimoto K, Okada R, Kushioka J, Chijimatsu R, Takenaka S, Makino T, Sakai Y, Moriguchi Y, Otsuru S, Hart DA, Fujie H, Nakamura N, Yoshikawa H
Acta biomaterialia 2019 Mar 15;87:118-129
Acta biomaterialia 2019 Mar 15;87:118-129
Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice.
Gu L, Wang Y, Yang G, Tilyek A, Zhang C, Li S, Yu B, Chai C, Cao Z
Journal of ethnopharmacology 2019 Mar 1;231:302-310
Journal of ethnopharmacology 2019 Mar 1;231:302-310
Three kinds of corneal host cells contribute differently to corneal neovascularization.
Yu H, Sun L, Cui J, Li Y, Yan Y, Wei X, Wang C, Song F, Jiang W, Liu Y, Ge H, Qian H, Li X, Tang X, Liu P
EBioMedicine 2019 Jun;44:542-553
EBioMedicine 2019 Jun;44:542-553
EZH2-DNMT1-mediated epigenetic silencing of miR-142-3p promotes metastasis through targeting ZEB2 in nasopharyngeal carcinoma.
Li Y, He Q, Wen X, Hong X, Yang X, Tang X, Zhang P, Lei Y, Sun Y, Zhang J, Wang Y, Ma J, Liu N
Cell death and differentiation 2019 Jun;26(6):1089-1106
Cell death and differentiation 2019 Jun;26(6):1089-1106
RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma.
Gao J, Wang Y, Yang J, Zhang W, Meng K, Sun Y, Li Y, He QY
Cancers 2019 Jun 18;11(6)
Cancers 2019 Jun 18;11(6)
Role of PM2.5 in the development and progression of COPD and its mechanisms.
Zhao J, Li M, Wang Z, Chen J, Zhao J, Xu Y, Wei X, Wang J, Xie J
Respiratory research 2019 Jun 13;20(1):120
Respiratory research 2019 Jun 13;20(1):120
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Sun J, Su W, Zhao X, Shan T, Jin T, Guo Y, Li C, Li R, Zhou Y, Shan H, Sun X, Liang H
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial‑mesenchymal transition mediated by the FAK/AKT/MMPs axis.
Liu SQ, Xu CY, Wu WH, Fu ZH, He SW, Qin MB, Huang JA
International journal of oncology 2019 Jan;54(1):41-52
International journal of oncology 2019 Jan;54(1):41-52
Loss of TMEM126A promotes extracellular matrix remodeling, epithelial-to-mesenchymal transition, and breast cancer metastasis by regulating mitochondrial retrograde signaling.
Sun HF, Yang XL, Zhao Y, Tian Q, Chen MT, Zhao YY, Jin W
Cancer letters 2019 Jan;440-441:189-201
Cancer letters 2019 Jan;440-441:189-201
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Xin H, Wang C, Liu Z
BMC cancer 2019 Jan 8;19(1):30
BMC cancer 2019 Jan 8;19(1):30
Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling.
Shen M, Jiang YZ, Wei Y, Ell B, Sheng X, Esposito M, Kang J, Hang X, Zheng H, Rowicki M, Zhang L, Shih WJ, Celià-Terrassa T, Liu Y, Cristea I, Shao ZM, Kang Y
Cancer cell 2019 Jan 14;35(1):64-80.e7
Cancer cell 2019 Jan 14;35(1):64-80.e7
Protein kinase C inhibitor chelerythrine attenuates partial unilateral ureteral obstruction induced kidney injury in neonatal rats.
Shi B, Li S, Ju H, Liu X, Li D, Li Y
Life sciences 2019 Jan 1;216:85-91
Life sciences 2019 Jan 1;216:85-91
An improved cellular enucleation method with extracellular matrix and colchicine facilitates the study of nucleocytoplasmic interaction.
Chen Y, Xu LQ, Lin MJ, Zhang W, Zhang ZJ, Xu WC, Yang LJ, Wei CJ
European journal of cell biology 2019 Dec;98(5-8):151045
European journal of cell biology 2019 Dec;98(5-8):151045
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Hu Y, Zheng Y, Dai M, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Cell adhesion & migration 2019 Dec;13(1):285-292
Cell adhesion & migration 2019 Dec;13(1):285-292
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration.
Zhou Y, Liu S, Zhao M, Wang C, Li L, Yuan Y, Li L, Liao G, Bresette W, Zhang J, Chen Y, Cheng J, Lu Y, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2019 Dec 28;316:93-104
Journal of controlled release : official journal of the Controlled Release Society 2019 Dec 28;316:93-104
Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.
Esfahani MS, Lee LJ, Jeon YJ, Flynn RA, Stehr H, Hui AB, Ishisoko N, Kildebeck E, Newman AM, Bratman SV, Porteus MH, Chang HY, Alizadeh AA, Diehn M
Nature communications 2019 Dec 13;10(1):5712
Nature communications 2019 Dec 13;10(1):5712
MicroRNA-432 is downregulated in cervical cancer and directly targets FN1 to inhibit cell proliferation and invasion.
Wang S, Gao B, Yang H, Liu X, Wu X, Wang W
Oncology letters 2019 Aug;18(2):1475-1482
Oncology letters 2019 Aug;18(2):1475-1482
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, Wang C, Gao M
Molecular medicine reports 2019 Apr;19(4):3168-3178
Molecular medicine reports 2019 Apr;19(4):3168-3178
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Li Y, Chen X, Cui Y, Wei Q, Chen S, Wang X
Oncology letters 2019 Apr;17(4):3701-3708
Oncology letters 2019 Apr;17(4):3701-3708
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Liang H, Pan Z, Zhao X, Liu L, Sun J, Su X, Xu C, Zhou Y, Zhao D, Xu B, Li X, Yang B, Lu Y, Shan H
Theranostics 2018;8(4):1180-1194
Theranostics 2018;8(4):1180-1194
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
He FF, You RY, Ye C, Lei CT, Tang H, Su H, Zhang C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Kindlin-2 regulates hepatic stellate cells activation and liver fibrogenesis.
Yu J, Hu Y, Gao Y, Li Q, Zeng Z, Li Y, Chen H
Cell death discovery 2018;4:34
Cell death discovery 2018;4:34
Cyclin G2 Suppresses Glomerulosclerosis by Regulating Canonical Wnt Signalling.
Zhao C, Gao J, Li S, Liu Q, Hou X, Liu S, Xing X, Sun M, Wang S, Luo Y
BioMed research international 2018;2018:6938482
BioMed research international 2018;2018:6938482
Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy.
Chen D, Han S, Zhu Y, Hu F, Wei Y, Wang G
International journal of nanomedicine 2018;13:3507-3527
International journal of nanomedicine 2018;13:3507-3527
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway.
Zhang H, Yang Y, Wang Y, Wang B, Li R
Drug design, development and therapy 2018;12:89-98
Drug design, development and therapy 2018;12:89-98
LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1.
Liang C, Yang Y, Guan J, Lv T, Qu S, Fu Q, Zhao H
Pathology, research and practice 2018 Sep;214(9):1474-1481
Pathology, research and practice 2018 Sep;214(9):1474-1481
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
Yang W, Chen Q, Xia R, Zhang Y, Shuai L, Lai J, You X, Jiang Y, Bie P, Zhang L, Zhang H, Bai L
Biomaterials 2018 Sep;177:52-66
Biomaterials 2018 Sep;177:52-66
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Zhao X, Sun J, Chen Y, Su W, Shan H, Li Y, Wang Y, Zheng N, Shan H, Liang H
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
Du Y, Zhang W, Liu S, Feng X, Gao F, Liu Q
Biochemical and biophysical research communications 2018 Sep 3;503(1):177-180
Biochemical and biophysical research communications 2018 Sep 3;503(1):177-180
NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis.
Li X, Li C, Tang Y, Huang Y, Cheng Q, Huang X, Zhao F, Hao C, Feng D, Xu J, Han J, Tang S, Liu W, Yue S, Luo Z
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L404-L421
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L404-L421
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Li X, Yu T, Shan H, Jiang H, Sun J, Zhao X, Su W, Yang L, Shan H, Liang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loop.
Jiang H, Chen Y, Yu T, Zhao X, Shan H, Sun J, Zhang L, Li X, Shan H, Liang H
American journal of physiology. Lung cellular and molecular physiology 2018 Oct 1;315(4):L563-L575
American journal of physiology. Lung cellular and molecular physiology 2018 Oct 1;315(4):L563-L575
The pro-metastasis effect of circANKS1B in breast cancer.
Zeng K, He B, Yang BB, Xu T, Chen X, Xu M, Liu X, Sun H, Pan Y, Wang S
Molecular cancer 2018 Nov 19;17(1):160
Molecular cancer 2018 Nov 19;17(1):160
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Jang IA, Kim EN, Lim JH, Kim MY, Ban TH, Yoon HE, Park CW, Chang YS, Choi BS
Nutrients 2018 Nov 12;10(11)
Nutrients 2018 Nov 12;10(11)
Towards an in vitro fibrogenesis model of human vocal fold scarring.
Graupp M, Rinner B, Frisch MT, Weiss G, Fuchs J, Sundl M, El-Heliebi A, Moser G, Kamolz LP, Karbiener M, Gugatschka M
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2018 May;275(5):1211-1218
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2018 May;275(5):1211-1218
Methanol fixed fibroblasts serve as feeder cells to maintain stem cells in the pluripotent state in vitro.
Ren Y, Ma Z, Yu T, Ling M, Wang H
Scientific reports 2018 May 17;8(1):7780
Scientific reports 2018 May 17;8(1):7780
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Zhang W, Sha Y, Wei K, Wu C, Ding D, Yang Y, Zhu C, Zhang Y, Ding G, Zhang A, Jia Z, Huang S
Oncotarget 2018 May 11;9(36):24199-24208
Oncotarget 2018 May 11;9(36):24199-24208
Fibronectin Facilitates Enterovirus 71 Infection by Mediating Viral Entry.
He QQ, Ren S, Xia ZC, Cheng ZK, Peng NF, Zhu Y
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling.
Li A, Peng R, Sun Y, Liu H, Peng H, Zhang Z
Cell death & disease 2018 May 1;9(5):461
Cell death & disease 2018 May 1;9(5):461
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
Kim EN, Kim MY, Lim JH, Kim Y, Shin SJ, Park CW, Kim YS, Chang YS, Yoon HE, Choi BS
Atherosclerosis 2018 Mar;270:123-131
Atherosclerosis 2018 Mar;270:123-131
RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis.
Wang Q, Yang X, Xu Y, Shen Z, Cheng H, Cheng F, Liu X, Wang R
Oncotarget 2018 Mar 6;9(18):14397-14412
Oncotarget 2018 Mar 6;9(18):14397-14412
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice.
Hsieh CC, Lin CL, He JT, Chiang M, Wang Y, Tsai YC, Hung CH, Chang PJ
Stem cell research & therapy 2018 Jul 4;9(1):183
Stem cell research & therapy 2018 Jul 4;9(1):183
Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, Wei X, Chen C, Liu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1586-1594
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Xiao Y, Chang W, Wu QQ, Jiang XH, Duan MX, Jin YG, Tang QZ
Planta medica 2018 Jan;84(2):91-99
Planta medica 2018 Jan;84(2):91-99
Regulation of pancreatic stellate cell activation by Notch3.
Song H, Zhang Y
BMC cancer 2018 Jan 5;18(1):36
BMC cancer 2018 Jan 5;18(1):36
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Shen H, Zhan M, Zhang Y, Huang S, Xu S, Huang X, He M, Yao Y, Man M, Wang J
Cell death & disease 2018 Jan 22;9(2):71
Cell death & disease 2018 Jan 22;9(2):71
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction.
He P, Li Z, Yue Z, Gao H, Feng G, Wang P, Huang Y, Luo W, Hong H, Liang L, Chen S, Liu P
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Molecular and cellular endocrinology 2018 Jan 15;460:1-13
Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.
Liu M, Xu H, Zhang L, Zhang C, Yang L, Ma E, Liu L, Li Y
Biochemical and biophysical research communications 2018 Jan 1;495(1):325-331
Biochemical and biophysical research communications 2018 Jan 1;495(1):325-331
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway.
Wang EM, Fan QL, Yue Y, Xu L
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
Medical science monitor : international medical journal of experimental and clinical research 2018 Feb 11;24:846-854
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
Tian H, Xu JY, Tian Y, Cao Y, Lian C, Ou Q, Wu B, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li W, Lu L, Xu GT
Experimental eye research 2018 Dec;177:160-172
Experimental eye research 2018 Dec;177:160-172
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
Lynch JM, Li B, Katoli P, Xiang C, Leehy B, Rangaswamy N, Saenz-Vash V, Wang YK, Lei H, Nicholson TB, Meredith E, Rice DS, Prasanna G, Chen A
The Journal of biological chemistry 2018 Dec 28;293(52):20137-20156
The Journal of biological chemistry 2018 Dec 28;293(52):20137-20156
Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation.
Yan P, Tang H, Chen X, Ji S, Jin W, Zhang J, Shen J, Deng H, Zhao X, Shen Q, Huang H
Bioscience reports 2018 Dec 21;38(6)
Bioscience reports 2018 Dec 21;38(6)
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Hu Y, Dai M, Zheng Y, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Clinical epigenetics 2018 Dec 12;10(1):154
Clinical epigenetics 2018 Dec 12;10(1):154
RGC-32 regulates reactive astrocytosis and extracellular matrix deposition in experimental autoimmune encephalomyelitis.
Tatomir A, Tegla CA, Martin A, Boodhoo D, Nguyen V, Sugarman AJ, Mekala A, Anselmo F, Talpos-Caia A, Cudrici C, Badea TC, Rus V, Rus H
Immunologic research 2018 Aug;66(4):445-461
Immunologic research 2018 Aug;66(4):445-461
Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype.
Li Y, Wang X, Zhang L, Yuan X, Hao J, Ni J, Hao L
International journal of molecular medicine 2018 Aug;42(2):861-872
International journal of molecular medicine 2018 Aug;42(2):861-872
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.
Liang H, Yu T, Han Y, Jiang H, Wang C, You T, Zhao X, Shan H, Yang R, Yang L, Shan H, Gu Y
Molecular cancer 2018 Aug 11;17(1):119
Molecular cancer 2018 Aug 11;17(1):119
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Zhao X, Sun J, Su W, Shan H, Zhang B, Wang Y, Shabanova A, Shan H, Liang H
International journal of molecular sciences 2018 Apr 9;19(4)
International journal of molecular sciences 2018 Apr 9;19(4)
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
Saxagliptin Attenuates Albuminuria by Inhibiting Podocyte Epithelial- to-Mesenchymal Transition via SDF-1α in Diabetic Nephropathy.
Chang YP, Sun B, Han Z, Han F, Hu SL, Li XY, Xue M, Yang Y, Chen L, Li CJ, Chen LM
Frontiers in pharmacology 2017;8:780
Frontiers in pharmacology 2017;8:780
The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis.
Peters S, Zitzelsperger E, Kuespert S, Iberl S, Heydn R, Johannesen S, Petri S, Aigner L, Thal DR, Hermann A, Weishaupt JH, Bruun TH, Bogdahn U
Frontiers in neurology 2017;8:669
Frontiers in neurology 2017;8:669
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, Song S, Li L, Sun P, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J
Oncotarget 2017 Sep 8;8(38):63461-63483
Oncotarget 2017 Sep 8;8(38):63461-63483
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Lei CT, Tang H, Ye C, You CQ, Zhang J, Zhang CY, Xiong W, Su H, Zhang C
Scientific reports 2017 Sep 4;7(1):10393
Scientific reports 2017 Sep 4;7(1):10393
FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma.
Cao TT, Xiang D, Liu BL, Huang TX, Tan BB, Zeng CM, Wang ZY, Ming XY, Zhang LY, Jin G, Li F, Wu JL, Guan XY, Lu D, Fu L
Oncotarget 2017 Sep 12;8(39):65957-65968
Oncotarget 2017 Sep 12;8(39):65957-65968
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.
Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Li Y, Fang S, Li Y, Zhu YH, Yuan YF, Guan XY
Cancer research 2017 Nov 1;77(21):5831-5845
Cancer research 2017 Nov 1;77(21):5831-5845
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
Shi H, Wang H, Fu S, Xu K, Zhang X, Xiao Y, Ye W
Investigative ophthalmology & visual science 2017 Mar 1;58(3):1478-1486
Investigative ophthalmology & visual science 2017 Mar 1;58(3):1478-1486
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Wu QQ, Xiao Y, Jiang XH, Yuan Y, Yang Z, Chang W, Bian ZY, Tang QZ
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
miR-206 inhibits FN1 expression and proliferation and promotes apoptosis of rat type II alveolar epithelial cells.
Duan J, Zhang X, Zhang S, Hua S, Feng Z
Experimental and therapeutic medicine 2017 Jun;13(6):3203-3208
Experimental and therapeutic medicine 2017 Jun;13(6):3203-3208
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
TGFβ-incurred epigenetic aberrations of miRNA and DNA methyltransferase suppress Klotho and potentiate renal fibrosis.
Yin S, Zhang Q, Yang J, Lin W, Li Y, Chen F, Cao W
Biochimica et biophysica acta. Molecular cell research 2017 Jul;1864(7):1207-1216
Biochimica et biophysica acta. Molecular cell research 2017 Jul;1864(7):1207-1216
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, Mao Y, Chen L, Zhang R, Li W
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Autophagy plays a role in FSTL1-induced epithelial mesenchymal transition and airway remodeling in asthma.
Liu T, Liu Y, Miller M, Cao L, Zhao J, Wu J, Wang J, Liu L, Li S, Zou M, Xu J, Broide DH, Dong L
American journal of physiology. Lung cellular and molecular physiology 2017 Jul 1;313(1):L27-L40
American journal of physiology. Lung cellular and molecular physiology 2017 Jul 1;313(1):L27-L40
Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease.
Zhang Q, Liu L, Lin W, Yin S, Duan A, Liu Z, Cao W
Kidney international 2017 Jan;91(1):144-156
Kidney international 2017 Jan;91(1):144-156
Phosphoinositide 3-kinase/protein kinase B/periostin mediated platelet-derived growth factor-induced cell proliferation and extracellular matrix production in lupus nephritis.
Zhao X, Hao J, Duan H, Rong Z, Li F
Experimental biology and medicine (Maywood, N.J.) 2017 Jan;242(2):160-168
Experimental biology and medicine (Maywood, N.J.) 2017 Jan;242(2):160-168
5-Aza-2'-deoxycytidine induces human Tenon's capsule fibroblasts differentiation and fibrosis by up-regulating TGF-β type I receptor.
Fu S, Sun L, Zhang X, Shi H, Xu K, Xiao Y, Ye W
Experimental eye research 2017 Dec;165:47-58
Experimental eye research 2017 Dec;165:47-58
MicroRNA-139 targets fibronectin 1 to inhibit papillary thyroid carcinoma progression.
Ye Y, Zhuang J, Wang G, He S, Ni J, Xia W
Oncology letters 2017 Dec;14(6):7799-7806
Oncology letters 2017 Dec;14(6):7799-7806
Low molecular weight fucoidan and its fractions inhibit renal epithelial mesenchymal transition induced by TGF-β1 or FGF-2.
Li X, Li X, Zhang Q, Zhao T
International journal of biological macromolecules 2017 Dec;105(Pt 2):1482-1490
International journal of biological macromolecules 2017 Dec;105(Pt 2):1482-1490
CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway.
Li XY, Wang SS, Han Z, Han F, Chang YP, Yang Y, Xue M, Sun B, Chen LM
Molecular therapy. Nucleic acids 2017 Dec 15;9:48-56
Molecular therapy. Nucleic acids 2017 Dec 15;9:48-56
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Ye C, Tang H, Zhao Z, Lei CT, You CQ, Zhang J, Gao P, He FF, Chen S, Wang YM, Zhang C, Su H
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy.
Yan N, Wen L, Peng R, Li H, Liu H, Peng H, Sun Y, Wu T, Chen L, Duan Q, Sun Y, Zhou Q, Wei L, Zhang Z
Journal of diabetes research 2016;2016:8738760
Journal of diabetes research 2016;2016:8738760
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice.
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Oxidative medicine and cellular longevity 2016;2016:6731093
Oxidative medicine and cellular longevity 2016;2016:6731093
Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells.
Sun B, Bai Y, Zhang L, Gong L, Qi X, Li H, Wang F, Chi X, Jiang Y, Shao S
PloS one 2016;11(9):e0163622
PloS one 2016;11(9):e0163622
Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms.
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PloS one 2016;11(3):e0152721
PloS one 2016;11(3):e0152721
Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation.
Guan R, Wang X, Zhao X, Song N, Zhu J, Wang J, Wang J, Xia C, Chen Y, Zhu D, Shen L
Scientific reports 2016 Oct 24;6:35696
Scientific reports 2016 Oct 24;6:35696
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
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Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
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Toxicology letters 2016 Nov 16;262:161-172
Toxicology letters 2016 Nov 16;262:161-172
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Free radical biology & medicine 2016 Mar;92:90-99
Free radical biology & medicine 2016 Mar;92:90-99
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Journal of molecular medicine (Berlin, Germany) 2016 Jun;94(6):655-65
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Biochemical and biophysical research communications 2016 Jul 15;476(1):35-41
Biochemical and biophysical research communications 2016 Jul 15;476(1):35-41
Glucocorticoid exposure in early placentation induces preeclampsia in rats via interfering trophoblast development.
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General and comparative endocrinology 2016 Jan 1;225:61-70
General and comparative endocrinology 2016 Jan 1;225:61-70
Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling.
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Toxicology and applied pharmacology 2016 Aug 1;304:1-8
Toxicology and applied pharmacology 2016 Aug 1;304:1-8
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis.
Liang C, Li X, Zhang L, Cui D, Quan X, Yang W
Experimental and molecular pathology 2015 Oct;99(2):279-85
Experimental and molecular pathology 2015 Oct;99(2):279-85
Pediatric Origins of Nephrolithiasis-Associated Atherosclerosis.
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The Journal of pediatrics 2015 Nov;167(5):1074-80.e2
The Journal of pediatrics 2015 Nov;167(5):1074-80.e2
MiR-25 promotes hepatocellular carcinoma cell growth, migration and invasion by inhibiting RhoGDI1.
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Oncotarget 2015 Nov 3;6(34):36231-44
Oncotarget 2015 Nov 3;6(34):36231-44
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
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IL-33 promotes airway remodeling and is a marker of asthma disease severity.
Guo Z, Wu J, Zhao J, Liu F, Chen Y, Bi L, Liu S, Dong L
The Journal of asthma : official journal of the Association for the Care of Asthma 2014 Oct;51(8):863-9
The Journal of asthma : official journal of the Association for the Care of Asthma 2014 Oct;51(8):863-9
Benzalkonium chloride induces subconjunctival fibrosis through the COX-2-modulated activation of a TGF-β1/Smad3 signaling pathway.
Huang C, Wang H, Pan J, Zhou D, Chen W, Li W, Chen Y, Liu Z
Investigative ophthalmology & visual science 2014 Nov 18;55(12):8111-22
Investigative ophthalmology & visual science 2014 Nov 18;55(12):8111-22
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
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Oncology letters 2014 Mar;7(3):658-662
miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM.
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Cancer research 2014 Jun 1;74(11):3031-42
Cancer research 2014 Jun 1;74(11):3031-42
Reduction of microRNA-206 contributes to the development of bronchopulmonary dysplasia through up-regulation of fibronectin 1.
Zhang X, Xu J, Wang J, Gortner L, Zhang S, Wei X, Song J, Zhang Y, Li Q, Feng Z
PloS one 2013;8(9):e74750
PloS one 2013;8(9):e74750
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Shu G, Mi X, Cai J, Zhang X, Yin W, Yang X, Li Y, Chen L, Deng X
Toxicology letters 2013 Oct 24;222(2):91-101
Toxicology letters 2013 Oct 24;222(2):91-101
Global profiling of proteolytically modified proteins in human metastatic hepatocellular carcinoma cell lines reveals CAPN2 centered network.
Shen C, Yu Y, Li H, Yan G, Liu M, Shen H, Yang P
Proteomics 2012 Jun;12(12):1917-27
Proteomics 2012 Jun;12(12):1917-27
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 15613-1-AP(FN1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15613-1-AP(FN1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Fibronectin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Fibronectin. This antibody recognizes human,mouse,rat antigen. The Fibronectin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
