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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 21891-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21891-1-AP, RRID:AB_10896826
- Product name
- P53 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P53 antibody (Cat. #21891-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Choline-induced SLC5A7 impairs colorectal cancer growth by stabilizing p53 protein.
The Role of RAD6B and PEDF in Retinal Degeneration.
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1.
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells.
P53 Activated by ER Stress Aggravates Caerulein-Induced Acute Pancreatitis Progression by Inducing Acinar Cell Apoptosis.
UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53.
LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer.
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
NKD1 correlates with a poor prognosis and inhibits cell proliferation by inducing p53 expression in hepatocellular carcinoma.
Yin Y, Jiang Z, Fu J, Li Y, Fang C, Yin X, Chen Y, Chen N, Li J, Ji Y, Su X, Qiu M, Huang W, Zhang B, Deng H, Dai L
Cancer letters 2022 Jan 28;525:55-66
Cancer letters 2022 Jan 28;525:55-66
The Role of RAD6B and PEDF in Retinal Degeneration.
Ye Q, Wang J, Liu X, Liu Z, BaZong L, Ma J, Shen R, Ye W, Zhang W, Wang D
Neuroscience 2022 Jan 1;480:19-31
Neuroscience 2022 Jan 1;480:19-31
PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway.
Zhang Y, Lv Z, Liu Y, Cao H, Yang J, Wang B
Oxidative medicine and cellular longevity 2021;2021:9980444
Oxidative medicine and cellular longevity 2021;2021:9980444
Arsenic sulfide reverses cisplatin resistance in non-small cell lung cancer in vitro and in vivo through targeting PD-L1.
Tian W, Sun Y, Cheng Y, Ma X, Du W, Shi W, Guo Q
Thoracic cancer 2021 Oct;12(19):2551-2563
Thoracic cancer 2021 Oct;12(19):2551-2563
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Zhang L, Liu M, Liu W, Hu C, Li H, Deng J, Cao Q, Wang Y, Hu W, Li Q
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Ge L, Xun C, Li W, Jin S, Liu Z, Zhuo Y, Duan D, Hu Z, Chen P, Lu M
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Journal of nanobiotechnology 2021 Nov 21;19(1):380
The intracellular domain of UNC5B facilities proliferation and metastasis of bladder cancer cells.
Huang Y, Zhang Z, Miao M, Kong C
Journal of cellular and molecular medicine 2021 Feb;25(4):2121-2135
Journal of cellular and molecular medicine 2021 Feb;25(4):2121-2135
P53 Activated by ER Stress Aggravates Caerulein-Induced Acute Pancreatitis Progression by Inducing Acinar Cell Apoptosis.
Zhou L, Tan JH, Zhou WY, Xu J, Ren SJ, Lin ZY, Chen XM, Zhang GW
Digestive diseases and sciences 2020 Nov;65(11):3211-3222
Digestive diseases and sciences 2020 Nov;65(11):3211-3222
UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53.
Huang Y, Zhu Y, Zhang Z, Li Z, Kong C
Cancer gene therapy 2020 Dec;27(12):934-947
Cancer gene therapy 2020 Dec;27(12):934-947
LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer.
Meng X, Sun W, Yu J, Zhou Y, Gu Y, Han J, Zhou L, Jiang X, Wang C
Molecular therapy. Nucleic acids 2020 Dec 4;22:1004-1015
Molecular therapy. Nucleic acids 2020 Dec 4;22:1004-1015
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Malouf GG, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Sgambato A, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G
Cancer cell 2019 Feb 11;35(2):204-220.e9
Cancer cell 2019 Feb 11;35(2):204-220.e9
NKD1 correlates with a poor prognosis and inhibits cell proliferation by inducing p53 expression in hepatocellular carcinoma.
Zhang S, Li J, Wang X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):14059-14067
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):14059-14067
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 21891-1-AP(TP53 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-TP53 (IP:21891-1-AP, 3ug; Detection:21891-1-AP 1:1000) with A431 cells lysate 1650ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TP53 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TP53. This antibody recognizes human,mouse,rat antigen. The TP53 antibody has been validated for the following applications: ELISA, IHC, IP, WB analysis.
