CABT-L1225

antibody from Creative Diagnostics

Targeting: CCR3 CC-CKR-3, CD193, CKR3, CMKBR3

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-L1225

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human CCR3 monoclonal antibody, clone 34I28M2

Antibody type

Monoclonal

Description

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

34I28M2

Concentration

0.5 mg/ml

Storage

-20°C, Avoid Freeze/Thaw Cycles