Antibody data
- Antibody Data
- Antigen structure
- References [51]
- Comments [0]
- Validations
- Flow cytometry [2]
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Validation data
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- Product number
- FAB197P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CCR7 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CCR7.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA58615
- Isotype
- IgG
- Antibody clone number
- 150503
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients.
Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults.
Increased frequency of CCR7+CD4+ T cells from patients with primary Sjögren's syndrome: An indicator of disease activity rather than of damage severity.
Impact of Vaccination on Distribution of T Cell Subsets in Antiretroviral-Treated HIV-Infected Children.
The Immunogenicity of Branded and Biosimilar Infliximab in Rheumatoid Arthritis According to Th9-Related Responses.
Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis.
E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner.
Humoral and cellular response after varicella vaccination in VZV IgG seronegative kidney transplant candidates.
Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC.
Cognate HLA absence in trans diminishes human NK cell education.
Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.
Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine.
Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profiling.
Different maturation cocktails provide dendritic cells with different chemoattractive properties.
Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire.
Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions.
Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-α monotherapy.
Dasatinib promotes Th1-type responses in granzyme B expressing T-cells.
A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa.
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
IL-2 phosphorylates STAT5 to drive IFN-γ production and activation of human dendritic cells.
Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis.
Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer.
Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells.
Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells.
The road to memory: an early rest for the long journey.
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.
Biomarkers on melanoma patient T cells associated with ipilimumab treatment.
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication.
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21.
IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells.
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.
Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients.
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures.
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.
Jimenez Vera E, Chew YV, Nicholson L, Burns H, Anderson P, Chen HT, Williams L, Keung K, Zanjani NT, Dervish S, Patrick E, Wang XM, Yi S, Hawthorne W, Alexander S, O'Connell PJ, Hu M
PloS one 2019;14(5):e0217163
PloS one 2019;14(5):e0217163
Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults.
Giacomet V, Masetti M, Nannini P, Forlanini F, Clerici M, Zuccotti GV, Trabattoni D
PloS one 2018;13(2):e0192638
PloS one 2018;13(2):e0192638
Increased frequency of CCR7+CD4+ T cells from patients with primary Sjögren's syndrome: An indicator of disease activity rather than of damage severity.
Wu C, Yang P, Liu H, Xiao W, Zhao L
Cytokine 2018 Oct;110:9-17
Cytokine 2018 Oct;110:9-17
Impact of Vaccination on Distribution of T Cell Subsets in Antiretroviral-Treated HIV-Infected Children.
Thitilertdecha P, Khowawisetsut L, Ammaranond P, Poungpairoj P, Tantithavorn V, Onlamoon N
Disease markers 2017;2017:5729639
Disease markers 2017;2017:5729639
The Immunogenicity of Branded and Biosimilar Infliximab in Rheumatoid Arthritis According to Th9-Related Responses.
Talotta R, Berzi A, Doria A, Batticciotto A, Ditto MC, Atzeni F, Sarzi-Puttini P, Trabattoni D
International journal of molecular sciences 2017 Oct 12;18(10)
International journal of molecular sciences 2017 Oct 12;18(10)
Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis.
Breuer O, Daum H, Cohen-Cymberknoh M, Unger S, Shoseyov D, Stepensky P, Keller B, Warnatz K, Kerem E
Respiratory medicine 2017 May;126:39-45
Respiratory medicine 2017 May;126:39-45
E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner.
Barisa M, Kramer AM, Majani Y, Moulding D, Saraiva L, Bajaj-Elliott M, Anderson J, Gustafsson K
Scientific reports 2017 Jun 5;7(1):2805
Scientific reports 2017 Jun 5;7(1):2805
Humoral and cellular response after varicella vaccination in VZV IgG seronegative kidney transplant candidates.
Kho MM, Zuijderwijk JM, van der Eijk AA, de Kuiper R, Boer-Verschragen MJ, Weimar W, van Besouw NM
Vaccine 2017 Jan 3;35(1):71-76
Vaccine 2017 Jan 3;35(1):71-76
Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC.
Ge C, Li R, Song H, Geng T, Yang J, Tan Q, Song L, Wang Y, Xue Y, Li Z, Dong S, Zhang Z, Zhang N, Guo J, Hua L, Chen S, Song X
BMC cancer 2017 Dec 21;17(1):884
BMC cancer 2017 Dec 21;17(1):884
Cognate HLA absence in trans diminishes human NK cell education.
Landtwing V, Raykova A, Pezzino G, Béziat V, Marcenaro E, Graf C, Moretta A, Capaul R, Zbinden A, Ferlazzo G, Malmberg KJ, Chijioke O, Münz C
The Journal of clinical investigation 2016 Oct 3;126(10):3772-3782
The Journal of clinical investigation 2016 Oct 3;126(10):3772-3782
Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.
Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR
mBio 2016 May 31;7(3)
mBio 2016 May 31;7(3)
Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine.
Berry N, Manoussaka M, Ham C, Ferguson D, Tudor H, Mattiuzzo G, Klaver B, Page M, Stebbings R, Das AT, Berkhout B, Almond N, Cranage MP
PLoS pathogens 2016 Dec;12(12):e1006083
PLoS pathogens 2016 Dec;12(12):e1006083
Characterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profiling.
Billingsley JM, Rajakumar PA, Connole MA, Salisch NC, Adnan S, Kuzmichev YV, Hong HS, Reeves RK, Kang HJ, Li W, Li Q, Haase AT, Johnson RP
PLoS pathogens 2015 Mar;11(3):e1004740
PLoS pathogens 2015 Mar;11(3):e1004740
Different maturation cocktails provide dendritic cells with different chemoattractive properties.
Massa C, Thomas C, Wang E, Marincola F, Seliger B
Journal of translational medicine 2015 Jun 3;13:175
Journal of translational medicine 2015 Jun 3;13:175
Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire.
Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, Marchant A, Vermijlen D
Proceedings of the National Academy of Sciences of the United States of America 2015 Feb 10;112(6):E556-65
Proceedings of the National Academy of Sciences of the United States of America 2015 Feb 10;112(6):E556-65
Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions.
Seifert M, Przekopowitz M, Taudien S, Lollies A, Ronge V, Drees B, Lindemann M, Hillen U, Engler H, Singer BB, Küppers R
Proceedings of the National Academy of Sciences of the United States of America 2015 Feb 10;112(6):E546-55
Proceedings of the National Academy of Sciences of the United States of America 2015 Feb 10;112(6):E546-55
Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-α monotherapy.
Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, Vakkila J, Mustjoki S
PloS one 2014;9(1):e87794
PloS one 2014;9(1):e87794
Dasatinib promotes Th1-type responses in granzyme B expressing T-cells.
Kreutzman A, Ilander M, Porkka K, Vakkila J, Mustjoki S
Oncoimmunology 2014;3:e28925
Oncoimmunology 2014;3:e28925
A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa.
Melum GR, Farkas L, Scheel C, Van Dieren B, Gran E, Liu YJ, Johansen FE, Jahnsen FL, Baekkevold ES
The Journal of allergy and clinical immunology 2014 Sep;134(3):613-621.e7
The Journal of allergy and clinical immunology 2014 Sep;134(3):613-621.e7
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
IL-2 phosphorylates STAT5 to drive IFN-γ production and activation of human dendritic cells.
Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5660-70
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5660-70
Human regulatory T cells lack the cyclophosphamide-extruding transporter ABCB1 and are more susceptible to cyclophosphamide-induced apoptosis.
Dimeloe S, Frick C, Fischer M, Gubser PM, Razik L, Bantug GR, Ravon M, Langenkamp A, Hess C
European journal of immunology 2014 Dec;44(12):3614-20
European journal of immunology 2014 Dec;44(12):3614-20
Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer.
Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, Tsukinaga S, Odahara S, Koyama S, Imazu H, Uchiyama K, Kajihara M, Arakawa H, Misawa T, Toyama Y, Yanagisawa S, Ikegami M, Kan S, Hayashi K, Komita H, Kamata Y, Ito M, Ishidao T, Yusa S, Shimodaira S, Gong J, Sugiyama H, Ohkusa T, Tajiri H
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Aug 15;20(16):4228-39
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Aug 15;20(16):4228-39
Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells.
Wölfl M, Greenberg PD
Nature protocols 2014 Apr;9(4):950-66
Nature protocols 2014 Apr;9(4):950-66
Manipulating the expression of chemokine receptors enhances delivery and activity of cytokine-induced killer cells.
Zou Y, Li F, Hou W, Sampath P, Zhang Y, Thorne SH
British journal of cancer 2014 Apr 15;110(8):1992-9
British journal of cancer 2014 Apr 15;110(8):1992-9
The road to memory: an early rest for the long journey.
Ho LP, Yit PS, Ng LH, Linn YC, Zhao Y, Sun L, Ling KL, Chai Koh MB, Monica Shih MC, Li S, Wang XY, Tien SL, Goh YT
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5603-14
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5603-14
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Cerdeira AS, Rajakumar A, Royle CM, Lo A, Husain Z, Thadhani RI, Sukhatme VP, Karumanchi SA, Kopcow HD
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Pertussis circulation has increased T-cell immunity during childhood more than a second acellular booster vaccination in Dutch children 9 years of age.
Schure RM, de Rond L, Oztürk K, Hendrikx L, Sanders E, Berbers G, Buisman AM
PloS one 2012;7(7):e41928
PloS one 2012;7(7):e41928
Biomarkers on melanoma patient T cells associated with ipilimumab treatment.
Wang W, Yu D, Sarnaik AA, Yu B, Hall M, Morelli D, Zhang Y, Zhao X, Weber JS
Journal of translational medicine 2012 Jul 12;10:146
Journal of translational medicine 2012 Jul 12;10:146
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Badr G, Lefevre EA, Mohany M
PloS one 2011;6(9):e23741
PloS one 2011;6(9):e23741
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, Traidl-Hoffman C, Behrendt H, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication.
Damås JK, Landrø L, Fevang B, Heggelund L, Tjønnfjord GE, Fløisand Y, Halvorsen B, Frøland SS, Aukrust P
Clinical and experimental immunology 2009 Sep;157(3):400-7
Clinical and experimental immunology 2009 Sep;157(3):400-7
Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
Ahern D, Lloyd CM, Robinson DS
Allergy 2009 Aug;64(8):1121-9
Allergy 2009 Aug;64(8):1121-9
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
Nature immunology 2009 Aug;10(8):857-63
Nature immunology 2009 Aug;10(8):857-63
Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21.
Ansén S, Butler MO, Berezovskaya A, Murray AP, Stevenson K, Nadler LM, Hirano N
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6125-36
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Oct 1;14(19):6125-36
IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
Jasny E, Eisenblätter M, Mätz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R
Journal of immunology (Baltimore, Md. : 1950) 2008 May 15;180(10):6629-39
Journal of immunology (Baltimore, Md. : 1950) 2008 May 15;180(10):6629-39
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
Pokkali S, Das SD, R L
Cytokine 2008 Mar;41(3):307-14
Cytokine 2008 Mar;41(3):307-14
BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells.
Badr G, Borhis G, Lefevre EA, Chaoul N, Deshayes F, Dessirier V, Lapree G, Tsapis A, Richard Y
Blood 2008 Mar 1;111(5):2744-54
Blood 2008 Mar 1;111(5):2744-54
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, Kanamori A, Kannagi R, Fujimoto J, Muroi K, Furukawa Y, Nakamura M
Cancer research 2008 Feb 1;68(3):790-9
Cancer research 2008 Feb 1;68(3):790-9
Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Aug;22(8):2747-57
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008 Aug;22(8):2747-57
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, O'Shea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS
The Journal of experimental medicine 2008 Aug 4;205(8):1797-805
The Journal of experimental medicine 2008 Aug 4;205(8):1797-805
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F
Nature immunology 2007 Sep;8(9):942-9
Nature immunology 2007 Sep;8(9):942-9
Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients.
Lécureuil C, Combadière B, Mazoyer E, Bonduelle O, Samri A, Autran B, Debré P, Combadière C
Blood 2007 May 1;109(9):3649-57
Blood 2007 May 1;109(9):3649-57
Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus.
Kaur A, Sanford HB, Garry D, Lang S, Klumpp SA, Watanabe D, Bronson RT, Lifson JD, Rosati M, Pavlakis GN, Felber BK, Knipe DM, Desrosiers RC
Virology 2007 Jan 20;357(2):199-214
Virology 2007 Jan 20;357(2):199-214
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
International journal of cancer 2006 May 1;118(9):2147-57
International journal of cancer 2006 May 1;118(9):2147-57
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.
Eksteen B, Miles A, Curbishley SM, Tselepis C, Grant AJ, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):593-603
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):593-603
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
Blood 2006 Aug 1;108(3):947-55
Blood 2006 Aug 1;108(3):947-55
In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures.
Godfrey WR, Ge YG, Spoden DJ, Levine BL, June CH, Blazar BR, Porter SB
Blood 2004 Jul 15;104(2):453-61
Blood 2004 Jul 15;104(2):453-61
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Liu LY, Jarjour NN, Busse WW, Kelly EA
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.
Kivisäkk P, Mahad DJ, Callahan MK, Trebst C, Tucky B, Wei T, Wu L, Baekkevold ES, Lassmann H, Staugaitis SM, Campbell JJ, Ransohoff RM
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8389-94
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8389-94
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR7 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) and either (A) Mouse Anti-Human CCR7 PE-conjugated Monoclonal Antibody (Catalog # FAB197P) or (B) Mouse IgG2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR7 in HEK293 Human Cell Line Transfected with Human CCR7 and eGFP by Flow Cytometry. The specificity of Mouse Anti-Human CCR7 Clone 150503 was demonstrated by its ability to react with (A) HEK293 human embryonic kidney cell line transfected with human CCR7 and not react with (B) irrelevant HEK293 transfectants. Antibody binding was monitored using Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B).