BS1385

antibody from Bioworld Technology, Inc

Targeting: MT-ND1 MTND1, NAD1, ND1

Western blot (Data presented on provider website)

Antibody Data

Product number

BS1385

Provider

Bioworld Technology, Inc

Product name

ND1 polyclonal antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to amino acids 189-202 of Mouse ND1.

Description

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.