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- References [13]
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- Product number
- 11049-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11049-1-AP, RRID:AB_2140649
- Product name
- MEK1/2 antibody
- Antibody type
- Polyclonal
- Description
- MEK1/2 antibody (Cat. #11049-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miR-34a-5p functions as a tumor suppressor in head and neck squamous cell cancer progression by targeting Flotillin-2.
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations.
BPTES inhibits anthrax lethal toxin-induced inflammatory response.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway.
hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promising diagnostic marker in human bladder urothelial carcinomas.
Li X, Zhao S, Fu Y, Zhang P, Zhang Z, Cheng J, Liu L, Jiang H
International journal of biological sciences 2021;17(15):4327-4339
International journal of biological sciences 2021;17(15):4327-4339
Trametinib Inhibits the Growth and Aerobic Glycolysis of Glioma Cells by Targeting the PKM2/c-Myc Axis.
Gao M, Yang J, Gong H, Lin Y, Liu J
Frontiers in pharmacology 2021;12:760055
Frontiers in pharmacology 2021;12:760055
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
Huang S, Tan Z, Cai J, Wang Z, Tian Y
Pharmaceutical biology 2021 Dec;59(1):584-593
Pharmaceutical biology 2021 Dec;59(1):584-593
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.
Du J, Dong Z, Tan L, Tan M, Zhang F, Zhang K, Pan G, Li C, Shi S, Zhang Y, Liu Y, Cui H
Frontiers in cell and developmental biology 2020;8:607757
Frontiers in cell and developmental biology 2020;8:607757
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
Down-regulation of the insulin signaling pathway by SHC may correlate with congenital heart disease in Chinese populations.
Luo Z, Xu L, Lu J, Shen Y, Tang Y, Wang X, Wu Y, Sun H, Guo T
Clinical science (London, England : 1979) 2020 Feb 14;134(3):349-358
Clinical science (London, England : 1979) 2020 Feb 14;134(3):349-358
BPTES inhibits anthrax lethal toxin-induced inflammatory response.
Wang J, Yang D, Shen X, Wang J, Liu X, Lin J, Zhong J, Zhao Y, Qi Z
International immunopharmacology 2020 Aug;85:106664
International immunopharmacology 2020 Aug;85:106664
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Li W, Cui K, Prochownik EV, Li Y
Cell death & disease 2018 May 1;9(5):482
Cell death & disease 2018 May 1;9(5):482
SOX9 was involved in TKIs resistance in renal cell carcinoma via Raf/MEK/ERK signaling pathway.
Li XL, Chen XQ, Zhang MN, Chen N, Nie L, Xu M, Gong J, Shen PF, Su ZZ, Weng X, Tan JY, Zhao T, Zeng H, Zhou Q
International journal of clinical and experimental pathology 2015;8(4):3871-81
International journal of clinical and experimental pathology 2015;8(4):3871-81
hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promising diagnostic marker in human bladder urothelial carcinomas.
Wang Y, Luo H, Li Y, Chen T, Wu S, Yang L
Molecular medicine reports 2012 Jan;5(1):260-5
Molecular medicine reports 2012 Jan;5(1):260-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MEK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MEK2. This antibody recognizes human,mouse,rat antigen. The MEK2 antibody has been validated for the following applications: ELISA, WB analysis.
