Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 12919-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12919-1-AP, RRID:AB_2237469
- Product name
- PKC Beta antibody
- Antibody type
- Polyclonal
- Description
- PKC Beta antibody (Cat. #12919-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prostaglandin E3 attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization.
LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.
Prenatal hypoxia attenuated contraction of offspring coronary artery associated with decreased PKCβ Ser660 phosphorylation and intracellular calcium.
Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling.
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats.
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke.
Effect of corticision on orthodontic tooth movement in a rat model as assessed by RNA sequencing.
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway.
Cui J, Shan K, Yang Q, Qi Y, Qu H, Li J, Wang R, Jia L, Chen W, Feng N, Chen YQ
Journal of cellular and molecular medicine 2021 Jun;25(12):5586-5601
Journal of cellular and molecular medicine 2021 Jun;25(12):5586-5601
LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.
Su X, Wei J, Qi H, Jin M, Zhang Q, Zhang Y, Zhang C, Yang R
Inflammatory bowel diseases 2021 Jul 27;27(8):1302-1315
Inflammatory bowel diseases 2021 Jul 27;27(8):1302-1315
Prenatal hypoxia attenuated contraction of offspring coronary artery associated with decreased PKCβ Ser660 phosphorylation and intracellular calcium.
Chen X, Qi L, Su H, He Y, Li N, Gao Q, Li H, Xu T, Lu L, Xu Z, Tang J
Life sciences 2020 Nov 15;261:118364
Life sciences 2020 Nov 15;261:118364
Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling.
Snow JB, Norton CE, Sands MA, Weise-Cross L, Yan S, Herbert LM, Sheak JR, Gonzalez Bosc LV, Walker BR, Kanagy NL, Jernigan NL, Resta TC
American journal of respiratory cell and molecular biology 2020 Jun;62(6):732-746
American journal of respiratory cell and molecular biology 2020 Jun;62(6):732-746
In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.
Su H, Chen X, Zhang Y, Qi L, He Y, Lv J, Zhang Y, Li X, Tang J, Xu Z
The Journal of endocrinology 2020 Jan;244(1):213-222
The Journal of endocrinology 2020 Jan;244(1):213-222
PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats.
Sheak JR, Yan S, Weise-Cross L, Ahmadian R, Walker BR, Jernigan NL, Resta TC
American journal of physiology. Heart and circulatory physiology 2020 Feb 1;318(2):H470-H483
American journal of physiology. Heart and circulatory physiology 2020 Feb 1;318(2):H470-H483
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Zhang J, Zhang Q, Chen X, Liu Y, Xue J, Dahan A, Zhang H, Chai Y
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
p66Shc Mediates Mitochondrial Dysfunction Dependent on PKC Activation in Airway Epithelial Cells Induced by Cigarette Smoke.
Zhang M, Tang J, Shan H, Zhang Q, Yang X, Zhang J, Li Y
Oxidative medicine and cellular longevity 2018;2018:5837123
Oxidative medicine and cellular longevity 2018;2018:5837123
Effect of corticision on orthodontic tooth movement in a rat model as assessed by RNA sequencing.
Gu Q, Guo S, Wang D, Zhou T, Wang L, Wang Z, Ma J
Journal of molecular histology 2017 Jun;48(3):199-208
Journal of molecular histology 2017 Jun;48(3):199-208
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Wu JF, Ji J, Dong SY, Li BB, Yu ML, Wu DD, Tao L, Tong XH
Oncology reports 2016 Dec;36(6):3251-3258
Oncology reports 2016 Dec;36(6):3251-3258
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, Liu R, He L
Scientific reports 2014 Jul 1;4:5518
Scientific reports 2014 Jul 1;4:5518
Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway.
Luo W, Wang X, Zheng L, Zhan Y, Zhang D, Zhang J, Zhang Y
Journal of cellular and molecular medicine 2013 Oct;17(10):1316-24
Journal of cellular and molecular medicine 2013 Oct;17(10):1316-24
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12919-1-AP(PRKCB antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 12919-1-AP(PRKCB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PKC beta antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PKC beta. This antibody recognizes human, mouse, rat antigen. The PKC beta antibody has been validated for the following applications: ELISA, WB, IHC analysis.