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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- PAB2144 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2144, RRID:AB_1574603
- Product name
- EIF2AK2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of EIF2AK2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Activation of the cell stress kinase PKR in Alzheimer's disease and human amyloid precursor protein transgenic mice.
The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC.
Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR.
Peel AL, Bredesen DE
Neurobiology of disease 2003 Oct;14(1):52-62
Neurobiology of disease 2003 Oct;14(1):52-62
The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC.
Pang Q, Christianson TA, Keeble W, Koretsky T, Bagby GC
The Journal of biological chemistry 2002 Dec 20;277(51):49638-43
The Journal of biological chemistry 2002 Dec 20;277(51):49638-43
Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR.
Kim SH, Gunnery S, Choe JK, Mathews MB
Oncogene 2002 Dec 12;21(57):8741-8
Oncogene 2002 Dec 12;21(57):8741-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The EIF2AK2 polyclonal antibody (Cat # PAB2144) is used in Western blot to detect EIF2AK2 in mouse uterus tissue lysate (Lane 1) and HepG2 cell lysate (Lane 2) .
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of EIF2AK2 (arrow) using EIF2AK2 polyclonal antibody (Cat # PAB2144). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EIF2AK2 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with EIF2AK2 polyclonal antibody (Cat # PAB2144) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
