CABT-L1607

antibody from Creative Diagnostics

Targeting: STAT2 STAT113

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-L1607

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human STAT2 monoclonal antibody, clone 2I20M20

Antibody type

Monoclonal

Description

STAT2 proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors. STAT2, STAT1, and ISGF3G are involved in activating the transcription of IFN stimulated genes that triggers cellular resistance to viral infections. Cytoplasmic STAT2 is tyrosine phosphorylated by JAK kinase upon IFN engagement to IFN receptors, and translocated to the nucleus to act as a transcription factor. In humans, the gene is located on the q arm of the chromosome 12. Splicing variants produce two isoforms for human STAT2.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2I20M20

Concentration

0.5 mg/ml

Storage

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C