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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- sc-434 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-434, RRID:AB_627642
- Product name
- Anti-FYN
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
Submitted references c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.
IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR.
The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.
Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.
Regulation of the Src family kinase Lck by Hsp90 and ubiquitination.
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.
Nitric Oxide Synthesis and Regional Cerebral Blood Flow Responses to Hypercapnia and Hypoxia in the Rat
Thien CB, Dagger SA, Steer JH, Koentgen F, Jansen ES, Scott CL, Langdon WY
The Journal of biological chemistry 2010 Apr 2;285(14):10969-81
The Journal of biological chemistry 2010 Apr 2;285(14):10969-81
IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR.
Weinlich S, Hüttelmaier S, Schierhorn A, Behrens SE, Ostareck-Lederer A, Ostareck DH
RNA (New York, N.Y.) 2009 Aug;15(8):1528-42
RNA (New York, N.Y.) 2009 Aug;15(8):1528-42
The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.
Marchetti S, Gamas P, Belhacène N, Grosso S, Pradelli LA, Colosetti P, Johansen C, Iversen L, Deckert M, Luciano F, Hofman P, Ortonne N, Khemis A, Mari B, Ortonne JP, Ricci JE, Auberger P
The EMBO journal 2009 Aug 19;28(16):2449-60
The EMBO journal 2009 Aug 19;28(16):2449-60
Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.
Vacaresse N, Møller B, Danielsen EM, Okada M, Sap J
The Journal of biological chemistry 2008 Dec 19;283(51):35815-24
The Journal of biological chemistry 2008 Dec 19;283(51):35815-24
Regulation of the Src family kinase Lck by Hsp90 and ubiquitination.
Giannini A, Bijlmakers MJ
Molecular and cellular biology 2004 Jul;24(13):5667-76
Molecular and cellular biology 2004 Jul;24(13):5667-76
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.
Labrecque L, Royal I, Surprenant DS, Patterson C, Gingras D, Béliveau R
Molecular biology of the cell 2003 Jan;14(1):334-47
Molecular biology of the cell 2003 Jan;14(1):334-47
Nitric Oxide Synthesis and Regional Cerebral Blood Flow Responses to Hypercapnia and Hypoxia in the Rat
D. A. Pelligrino, H. M. Koenig, R. F. Albrecht
Journal of Cerebral Blood Flow & Metabolism 1993 Jan;13(1):80-87
Journal of Cerebral Blood Flow & Metabolism 1993 Jan;13(1):80-87
No comments: Submit comment
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Western blot analysis of antibody specificity using a routine panel composed of IgG/HSA-depleted human plasma and protein lysates from selected human tissues and cell lines.
- Validation comment
- No bands detected.
- Primary Ab dilution
- 1:500
- Secondary Ab dilution
- 1:7000
- Lane 1
- Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11
- Lane 2
- RT-4
- Lane 3
- U-251MG sp
- Lane 4
- Human Plasma
- Lane 5
- Liver
- Lane 6
- Tonsil
- Theoretical target weight
- [kDa] 61
Supportive validation
- Submitted by
- per
- Main image
- Experimental details
- Immunohistochemical staining of human lymph node shows cytoplasmic positivity in lymphoid cells outside reaction centra.
- Validation comment
- Staining pattern partly consistent with experimental and/or bioinformatic data.
