Antibody data
- Antibody Data
- Antigen structure
- References [106]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10929-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10929-2-AP, RRID:AB_2169568
- Product name
- AMPK Alpha 1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AMPK Alpha 1 antibody (Cat. #10929-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GLP-1-Induced AMPK Activation Inhibits PARP-1 and Promotes LXR-Mediated ABCA1 Expression to Protect Pancreatic β-Cells Against Cholesterol-Induced Toxicity Through Cholesterol Efflux.
Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway.
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
NmFGF1-Regulated Glucolipid Metabolism and Angiogenesis Improves Functional Recovery in a Mouse Model of Diabetic Stroke and Acts via the AMPK Signaling Pathway.
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Simvastatin-romidepsin combination kills bladder cancer cells synergistically.
Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson's disease mice.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
SIRT3 affects mitochondrial metabolic reprogramming via the AMPK-PGC-1α axis in the development of benign prostatic hyperplasia.
Cardioprotective responses to aerobic exercise-induced physiological hypertrophy in zebrafish heart.
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
SCFJFK is functionally linked to obesity and metabolic syndrome.
A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH.
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Naringin induces skeletal muscle fiber type transformation via AMPK/PGC-1α signaling pathway in mice and C2C12 myotubes.
Danqi Tablet () Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1α Pathway.
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish.
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene.
Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice.
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
S -1-Propenylcysteine, a sulfur compound in aged garlic extract, alleviates cold-induced reduction in peripheral blood flow in rat via activation of the AMPK/eNOS/NO pathway.
The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models.
Empagliflozin improves diabetic renal tubular injury by alleviating mitochondrial fission via AMPK/SP1/PGAM5 pathway.
The immunomodulatory role of irisin on osteogenesis via AMPK-mediated macrophage polarization.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma.
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells.
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Sulforaphane delays diabetes-induced retinal photoreceptor cell degeneration.
Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression.
Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice.
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Exogenous hydrogen sulfide mitigates NLRP3 inflammasome-mediated inflammation through promoting autophagy via the AMPK-mTOR pathway.
The NQO1/PKLR axis promotes lymph node metastasis and breast cancer progression by modulating glycolytic reprogramming.
Restoring mitochondrial biogenesis with metformin attenuates β-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype via inhibition of PDK4/oxidative stress-mediated apoptosis.
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy.
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice.
Panobinostat and Nelfinavir Inhibit Renal Cancer Growth by Inducing Endoplasmic Reticulum Stress.
Anti-hypertrophy effect of atorvastatin on myocardium depends on AMPK activation-induced miR-143-3p suppression via Foxo1.
Effect of Omega-3 Fatty Acid on STAMP2 Expression in the Heart and Kidney of 5/6 Nephrectomy Rat Model.
MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.
Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma.
3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5.
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
Delanzomib Interacts with Ritonavir Synergistically to Cause Endoplasmic Reticulum Stress in Renal Cancer Cells.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway.
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
9-O-benzoyl-substituted berberine exerts a triglyceride-lowering effect through AMPK signaling pathway in human hepatoma HepG2 cells.
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats.
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats.
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Chronic metformin treatment facilitates seizure termination.
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
AMP-activated protein kinase and cAMP response element-binding protein activity are associated with distinct postoperative behavioral changes in rats.
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
The Effect of Hippocampal Cognitive Impairment and XIAP on Glucose and Lipids Metabolism in Rats.
Activation of AMPK α2 inhibits airway smooth muscle cells proliferation.
Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway.
Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis.
Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth.
Li R, Sun X, Li P, Li W, Zhao L, Zhu L, Zhu S
Frontiers in cell and developmental biology 2021;9:646113
Frontiers in cell and developmental biology 2021;9:646113
Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway.
Song Y, Zhang Y, Zhang P, Yu P, Shang X, Lu Y, Li Y, Gao H
Oxidative medicine and cellular longevity 2021;2021:6693921
Oxidative medicine and cellular longevity 2021;2021:6693921
Geniposide from Gardenia jasminoides var. radicans Makino Attenuates Myocardial Injury in Spontaneously Hypertensive Rats via Regulating Apoptotic and Energy Metabolism Signalling Pathway.
Hou Y, Yuan P, Fu Y, Zhang Q, Gao L, Wei Y, Zheng X, Feng W
Drug design, development and therapy 2021;15:949-962
Drug design, development and therapy 2021;15:949-962
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
Liu X, Xu Y, Cheng S, Zhou X, Zhou F, He P, Hu F, Zhang L, Chen Y, Jia Y
Frontiers in pharmacology 2021;12:687394
Frontiers in pharmacology 2021;12:687394
NmFGF1-Regulated Glucolipid Metabolism and Angiogenesis Improves Functional Recovery in a Mouse Model of Diabetic Stroke and Acts via the AMPK Signaling Pathway.
Zhao Y, Ye S, Lin J, Liang F, Chen J, Hu J, Chen K, Fang Y, Chen X, Xiong Y, Lin L, Tan X
Frontiers in pharmacology 2021;12:680351
Frontiers in pharmacology 2021;12:680351
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Simvastatin-romidepsin combination kills bladder cancer cells synergistically.
Okubo K, Miyai K, Kato K, Asano T, Sato A
Translational oncology 2021 Sep;14(9):101154
Translational oncology 2021 Sep;14(9):101154
Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson's disease mice.
Bai X, Zhang X, Fang R, Wang J, Ma Y, Liu Z, Dong H, Li Q, Ge J, Yu M, Fei J, Sun R, Huang F
Aging 2021 Sep 20;13(18):22390-22411
Aging 2021 Sep 20;13(18):22390-22411
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.
Zeng Y, Liang H, Guo Y, Feng Y, Yao Q
Journal of cellular physiology 2021 Oct;236(10):7088-7096
Journal of cellular physiology 2021 Oct;236(10):7088-7096
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154
Toxicology letters 2021 Oct 15;351:145-154
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Zou Y, Chen Z, Sun C, Yang D, Zhou Z, Peng X, Zheng L, Tang C
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
SIRT3 affects mitochondrial metabolic reprogramming via the AMPK-PGC-1α axis in the development of benign prostatic hyperplasia.
Li Y, Wang Q, Li J, Shi B, Liu Y, Wang P
The Prostate 2021 Nov;81(15):1135-1148
The Prostate 2021 Nov;81(15):1135-1148
Cardioprotective responses to aerobic exercise-induced physiological hypertrophy in zebrafish heart.
Chen Z, Zhou Z, Peng X, Sun C, Yang D, Li C, Zhu R, Zhang P, Zheng L, Tang C
The journal of physiological sciences : JPS 2021 Nov 8;71(1):33
The journal of physiological sciences : JPS 2021 Nov 8;71(1):33
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.
Hu Y, Chen H, Zhang L, Lin X, Li X, Zhuang H, Fan H, Meng T, He Z, Huang H, Gong Q, Zhu D, Xu Y, He P, Li L, Feng D
Autophagy 2021 May;17(5):1142-1156
Autophagy 2021 May;17(5):1142-1156
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Xie M, Xiong Z, Yin S, Xiong J, Li X, Jin L, Zhang F, Chen H, Lan P, Lian L
Digestive diseases and sciences 2021 May 19;
Digestive diseases and sciences 2021 May 19;
Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury.
An H, Hu Z, Chen Y, Cheng L, Shi J, Han L
Annals of translational medicine 2021 Mar;9(6):481
Annals of translational medicine 2021 Mar;9(6):481
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Free radical biology & medicine 2021 Mar;165:229-242
Free radical biology & medicine 2021 Mar;165:229-242
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Wang J, Li Z, Yang X, Qiao Y, Feng C, Yu S, Jing H, Liu W, Ren L, Duan Q, Li XQ, Cao W
Carbohydrate polymers 2021 Mar 1;255:117532
Carbohydrate polymers 2021 Mar 1;255:117532
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE-/- mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum.
Xue H, Cao H, Xing C, Feng J, Zhang L, Zhang C, Hu G, Yang F
Toxicology 2021 Jul;459:152855
Toxicology 2021 Jul;459:152855
SCFJFK is functionally linked to obesity and metabolic syndrome.
He L, Yan R, Yang Z, Zhang Y, Liu X, Yang J, Liu X, Liu X, Xia L, Wang Y, Wu J, Wu X, Shan L, Yang X, Liang J, Shang Y, Sun L
EMBO reports 2021 Jul 5;22(7):e52036
EMBO reports 2021 Jul 5;22(7):e52036
A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH.
Zhou J, Zhao Y, Guo YJ, Zhao YS, Liu H, Ren J, Li JR, Ji ES
Life sciences 2021 Jul 1;276:119403
Life sciences 2021 Jul 1;276:119403
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Gong X, Li T, Wan R, Sha L
International immunopharmacology 2021 Feb;91:107173
International immunopharmacology 2021 Feb;91:107173
Naringin induces skeletal muscle fiber type transformation via AMPK/PGC-1α signaling pathway in mice and C2C12 myotubes.
Xue Y, Huang Z, Chen X, Jia G, Zhao H, Liu G
Nutrition research (New York, N.Y.) 2021 Aug;92:99-108
Nutrition research (New York, N.Y.) 2021 Aug;92:99-108
Danqi Tablet () Regulates Energy Metabolism in Ischemic Heart Rat Model through AMPK/SIRT1-PGC-1α Pathway.
Meng H, Wang QY, Li N, He H, Lu WJ, Wang QX, Sun XQ, Jiao SH, Wang Y, Tu PF
Chinese journal of integrative medicine 2021 Aug;27(8):597-603
Chinese journal of integrative medicine 2021 Aug;27(8):597-603
Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway.
Pu JL, Huang ZT, Luo YH, Mou T, Li TT, Li ZT, Wei XF, Wu ZJ
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
Hepatobiliary & pancreatic diseases international : HBPD INT 2021 Aug;20(4):352-360
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Xiaoli F, Yaqing Z, Ruhui L, Xuan L, Aijie C, Yanli Z, Chen H, Lili C, Longquan S
Journal of hazardous materials 2021 Aug 15;416:126158
Journal of hazardous materials 2021 Aug 15;416:126158
Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish.
Sun CC, Zhou ZQ, Chen ZL, Zhu RK, Yang D, Peng XY, Zheng L, Tang CF
Biology 2021 Aug 10;10(8)
Biology 2021 Aug 10;10(8)
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Zhu Y, Wang C, Luo J, Hua S, Li D, Peng L, Liu H, Song L
Food & function 2021 Apr 7;12(7):3120-3131
Food & function 2021 Apr 7;12(7):3120-3131
Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene.
Wang Y, Zhao H, Liu Y, Li J, Nie X, Huang P, Xing M
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:116597
Environmental pollution (Barking, Essex : 1987) 2021 Apr 1;274:116597
Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice.
Ding X, Jian T, Li J, Lv H, Tong B, Li J, Meng X, Ren B, Chen J
Oxidative medicine and cellular longevity 2020;2020:9734560
Oxidative medicine and cellular longevity 2020;2020:9734560
Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway.
Jiang X, Ruan XL, Xue YX, Yang S, Shi M, Wang LN
Oxidative medicine and cellular longevity 2020;2020:8708236
Oxidative medicine and cellular longevity 2020;2020:8708236
FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.
Zhou B, Qiu Y, Wu N, Chen AD, Zhou H, Chen Q, Kang YM, Li YH, Zhu GQ
Oxidative medicine and cellular longevity 2020;2020:6384803
Oxidative medicine and cellular longevity 2020;2020:6384803
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis.
Zhang H, Tian F, Jiang P, Qian S, Dai X, Ma B, Wang M, Dai H, Sha X, Yang Z, Zhu X, Sun X
Frontiers in oncology 2020;10:614067
Frontiers in oncology 2020;10:614067
S -1-Propenylcysteine, a sulfur compound in aged garlic extract, alleviates cold-induced reduction in peripheral blood flow in rat via activation of the AMPK/eNOS/NO pathway.
Ushijima M, Kunimura K, Suzuki JI
Experimental and therapeutic medicine 2020 Sep;20(3):2815-2821
Experimental and therapeutic medicine 2020 Sep;20(3):2815-2821
The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models.
Wu H, Sun H, He Z, Chen X, Li Y, Zhao X, Kong W, Kong W
Experimental cell research 2020 Sep 1;394(1):112093
Experimental cell research 2020 Sep 1;394(1):112093
Empagliflozin improves diabetic renal tubular injury by alleviating mitochondrial fission via AMPK/SP1/PGAM5 pathway.
Liu X, Xu C, Xu L, Li X, Sun H, Xue M, Li T, Yu X, Sun B, Chen L
Metabolism: clinical and experimental 2020 Oct;111:154334
Metabolism: clinical and experimental 2020 Oct;111:154334
The immunomodulatory role of irisin on osteogenesis via AMPK-mediated macrophage polarization.
Ye W, Wang J, Lin D, Ding Z
International journal of biological macromolecules 2020 Mar 1;146:25-35
International journal of biological macromolecules 2020 Mar 1;146:25-35
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma.
Chu YD, Lin WR, Lin YH, Kuo WH, Tseng CJ, Lim SN, Huang YL, Huang SC, Wu TJ, Lin KH, Yeh CT
Cancers 2020 Jun 22;12(6)
Cancers 2020 Jun 22;12(6)
Low levels of AMPK promote epithelial-mesenchymal transition in lung cancer primarily through HDAC4- and HDAC5-mediated metabolic reprogramming.
Feng S, Zhang L, Liu X, Li G, Zhang B, Wang Z, Zhang H, Ma H
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
Journal of cellular and molecular medicine 2020 Jul;24(14):7789-7801
Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells.
Okubo K, Isono M, Miyai K, Asano T, Sato A
Cancer science 2020 Jan;111(1):112-126
Cancer science 2020 Jan;111(1):112-126
UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop.
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, Li G, Niu Z, Liu J, Chen D, Li Z, Fu Y, Qian C
Cell death & disease 2020 Jan 6;11(1):10
Cell death & disease 2020 Jan 6;11(1):10
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
You B, Dun Y, Zhang W, Jiang L, Li H, Xie M, Liu Y, Liu S
The Journal of endocrinology 2020 Feb;244(2):383-393
The Journal of endocrinology 2020 Feb;244(2):383-393
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
Sulforaphane delays diabetes-induced retinal photoreceptor cell degeneration.
Lv J, Bao S, Liu T, Wei L, Wang D, Ye W, Wang N, Song S, Li J, Chudhary M, Ren X, Kong L
Cell and tissue research 2020 Dec;382(3):477-486
Cell and tissue research 2020 Dec;382(3):477-486
Galectin-3 expression and secretion by tumor-associated macrophages in hypoxia promotes breast cancer progression.
Wang L, Li YS, Yu LG, Zhang XK, Zhao L, Gong FL, Yang XX, Guo XL
Biochemical pharmacology 2020 Aug;178:114113
Biochemical pharmacology 2020 Aug;178:114113
Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal mice.
Wang C, Le Y, Lu D, Zhao M, Dou X, Zhang Q
Journal of hazardous materials 2020 Apr 15;388:121732
Journal of hazardous materials 2020 Apr 15;388:121732
The balance of apoptosis and autophagy via regulation of the AMPK signal pathway in aging rat striatum during regular aerobic exercise.
Liu W, Wang Z, Xia Y, Kuang H, Liu S, Li L, Tang C, Yin D
Experimental gerontology 2019 Sep;124:110647
Experimental gerontology 2019 Sep;124:110647
Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells.
Lu J, Meng Z, Cheng B, Liu M, Tao S, Guan S
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Experimental and therapeutic medicine 2019 Oct;18(4):2965-2971
Lopinavir-Ritonavir Combination Induces Endoplasmic Reticulum Stress and Kills Urological Cancer Cells.
Okubo K, Isono M, Asano T, Sato A
Anticancer research 2019 Nov;39(11):5891-5901
Anticancer research 2019 Nov;39(11):5891-5901
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
Meng Z, Liu Q, Sun F, Qiao L
Lipids in health and disease 2019 Nov 4;18(1):191
Lipids in health and disease 2019 Nov 4;18(1):191
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, Jiang Q
Food & function 2019 May 22;10(5):2651-2657
Food & function 2019 May 22;10(5):2651-2657
Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/ GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice.
Li S, Huang Q, Zhang L, Qiao X, Zhang Y, Tang F, Li Z
European journal of pharmacology 2019 Jun 15;853:1-10
European journal of pharmacology 2019 Jun 15;853:1-10
APS could potentially activate hepatic insulin signaling in HFD-induced IR mice.
Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, Jiang R, Guo M, Han D, Liu B, Wang N, Li Y, Huang H, Zeng L, Gao Y, Li X, Wu Y
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Journal of molecular endocrinology 2019 Jul;63(1):77-91
Exogenous hydrogen sulfide mitigates NLRP3 inflammasome-mediated inflammation through promoting autophagy via the AMPK-mTOR pathway.
Wang H, Zhong P, Sun L
Biology open 2019 Jul 17;8(7)
Biology open 2019 Jul 17;8(7)
The NQO1/PKLR axis promotes lymph node metastasis and breast cancer progression by modulating glycolytic reprogramming.
Yang Y, Zhu G, Dong B, Piao J, Chen L, Lin Z
Cancer letters 2019 Jul 1;453:170-183
Cancer letters 2019 Jul 1;453:170-183
Restoring mitochondrial biogenesis with metformin attenuates β-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype via inhibition of PDK4/oxidative stress-mediated apoptosis.
Ma WQ, Sun XJ, Wang Y, Zhu Y, Han XQ, Liu NF
Molecular and cellular endocrinology 2019 Jan 5;479:39-53
Molecular and cellular endocrinology 2019 Jan 5;479:39-53
Chlorogenic Acid Stimulates the Thermogenesis of Brown Adipocytes by Promoting the Uptake of Glucose and the Function of Mitochondria.
Han X, Zhang Y, Guo J, You Y, Zhan J, Huang W
Journal of food science 2019 Dec;84(12):3815-3824
Journal of food science 2019 Dec;84(12):3815-3824
Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells.
Bao H, Zhang Q, Liu X, Song Y, Li X, Wang Z, Li C, Peng A, Gong R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14370-14381
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14370-14381
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Gu S, Hua H, Guo X, Jia Z, Zhang Y, Maslov LN, Zhang X, Ma H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Zhang J, Zhang Q, Chen X, Liu Y, Xue J, Dahan A, Zhang H, Chai Y
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy.
Fang J, Zhu Y, Wang H, Cao B, Fei M, Niu W, Zhou Y, Wang X, Li X, Zhou M
Frontiers in neuroscience 2018;12:1006
Frontiers in neuroscience 2018;12:1006
lncRNA DLEU1 contributes to tumorigenesis and development of endometrial carcinoma by targeting mTOR.
Du Y, Wang L, Chen S, Liu Y, Zhao Y
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Molecular carcinogenesis 2018 Sep;57(9):1191-1200
Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice.
Guo XF, Sinclair AJ, Kaur G, Li D
Prostaglandins, leukotrienes, and essential fatty acids 2018 Sep;136:47-55
Prostaglandins, leukotrienes, and essential fatty acids 2018 Sep;136:47-55
Panobinostat and Nelfinavir Inhibit Renal Cancer Growth by Inducing Endoplasmic Reticulum Stress.
Okubo K, Isono M, Asano T, Sato A
Anticancer research 2018 Oct;38(10):5615-5626
Anticancer research 2018 Oct;38(10):5615-5626
Anti-hypertrophy effect of atorvastatin on myocardium depends on AMPK activation-induced miR-143-3p suppression via Foxo1.
Yu B, Liu D, Zhang H, Xie D, Nie W, Shi K, Yang P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1390-1395
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1390-1395
Effect of Omega-3 Fatty Acid on STAMP2 Expression in the Heart and Kidney of 5/6 Nephrectomy Rat Model.
Lee HW, Lee SM, Lee MH, Son YK, Kim SE, An WS
Marine drugs 2018 Oct 23;16(11)
Marine drugs 2018 Oct 23;16(11)
MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.
Zeng N, Huang R, Li N, Jiang H, Li R, Wang F, Chen W, Xia M, Wang Q
Molecular and cellular endocrinology 2018 Oct 15;474:260-271
Molecular and cellular endocrinology 2018 Oct 15;474:260-271
Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma.
Dai J, Huang Q, Niu K, Wang B, Li Y, Dai C, Chen Z, Tao K, Dai J
Cancer medicine 2018 Nov;7(11):5691-5703
Cancer medicine 2018 Nov;7(11):5691-5703
3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5.
Chen Y, Wei L, Zhang X, Liu X, Chen Y, Zhang S, Zhou L, Li Q, Pan Q, Zhao S, Liu H
Oncology reports 2018 Nov;40(5):2435-2444
Oncology reports 2018 Nov;40(5):2435-2444
The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Gao J, Xiong R, Xiong D, Zhao W, Zhang S, Yin T, Zhang X, Jiang G, Yin Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Nov 26;24:8533-8543
Medical science monitor : international medical journal of experimental and clinical research 2018 Nov 26;24:8533-8543
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576
Cell death & disease 2018 May 1;9(5):576
AMPK alleviates endoplasmic reticulum stress by inducing the ER-chaperone ORP150 via FOXO1 to protect human bronchial cells from apoptosis.
Liu JQ, Zhang L, Yao J, Yao S, Yuan T
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
Biochemical and biophysical research communications 2018 Mar 4;497(2):564-570
Delanzomib Interacts with Ritonavir Synergistically to Cause Endoplasmic Reticulum Stress in Renal Cancer Cells.
Isono M, Sato A, Asano T, Okubo K, Asano T
Anticancer research 2018 Jun;38(6):3493-3500
Anticancer research 2018 Jun;38(6):3493-3500
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Zheng L, Yin L, Xu L, Qi Y, Li H, Xu Y, Han X, Liu K, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
LncRNA LOC730101 promotes osteosarcoma cell survival under energy stress.
Cheng G, Li B, Sun X, Cao Z, Zhang G, Zhao Z, Zhao Y, Yu Q, Liu W
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Biochemical and biophysical research communications 2018 Jan 29;496(1):1-6
Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway.
Zhao Y, Shi X, Ding C, Feng D, Li Y, Hu Y, Wang L, Gao D, Tian X, Yao J
Toxicology and applied pharmacology 2018 Jan 15;339:172-180
Toxicology and applied pharmacology 2018 Jan 15;339:172-180
Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells.
Li CF, Sun JX, Gao Y, Shi F, Pan YK, Wang YC, Sun XQ
Cell death & disease 2018 Feb 2;9(2):147
Cell death & disease 2018 Feb 2;9(2):147
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
9-O-benzoyl-substituted berberine exerts a triglyceride-lowering effect through AMPK signaling pathway in human hepatoma HepG2 cells.
Cao S, Yu S, Cheng L, Yan J, Zhu Y, Deng Y, Qiu F, Kang N
Environmental toxicology and pharmacology 2018 Dec;64:11-17
Environmental toxicology and pharmacology 2018 Dec;64:11-17
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.
Cheng B, Lu J, Li T, Meng Z, Liu M, Sun M, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Dec;122:143-150
Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway.
Yan J, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Sun H
Pharmacological research 2018 Apr;130:466-480
Pharmacological research 2018 Apr;130:466-480
Activation of AMP-activated protein kinase (AMPK) aggravated postoperative cognitive dysfunction and pathogenesis in aged rats.
Cao M, Fang J, Wang X, Wang Y, Duan K, Ye F, Ouyang W, Tong J
Brain research 2018 Apr 1;1684:21-29
Brain research 2018 Apr 1;1684:21-29
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control.
Dun Y, Liu S, Zhang W, Xie M, Qiu L
Oxidative medicine and cellular longevity 2017;2017:8024857
Oxidative medicine and cellular longevity 2017;2017:8024857
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Ran G, Ying L, Li L, Yan Q, Yi W, Ying C, Wu H, Ye X
PloS one 2017;12(7):e0180865
PloS one 2017;12(7):e0180865
SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats.
Zhou Y, Wang S, Li Y, Yu S, Zhao Y
Frontiers in molecular neuroscience 2017;10:443
Frontiers in molecular neuroscience 2017;10:443
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration.
Luo X, Dan Wang, Luo X, Zhu X, Wang G, Ning Z, Li Y, Ma X, Yang R, Jin S, Huang Y, Meng Y, Li X
Redox biology 2017 Oct;13:508-521
Redox biology 2017 Oct;13:508-521
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, Tan N
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Molecules (Basel, Switzerland) 2017 Nov 11;22(11)
Chronic metformin treatment facilitates seizure termination.
Yang Y, Zhu B, Zheng F, Li Y, Zhang Y, Hu Y, Wang X
Biochemical and biophysical research communications 2017 Mar 4;484(2):450-455
Biochemical and biophysical research communications 2017 Mar 4;484(2):450-455
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
La X, Zhang L, Li Z, Yang P, Wang Y
Oncotarget 2017 Mar 28;8(13):20909-20924
Oncotarget 2017 Mar 28;8(13):20909-20924
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Zhou S, Lu W, Chen L, Ge Q, Chen D, Xu Z, Shi D, Dai J, Li J, Ju H, Cao Y, Qin J, Chen S, Teng H, Jiang Q
Scientific reports 2017 Feb 22;7:43245
Scientific reports 2017 Feb 22;7:43245
AMP-activated protein kinase and cAMP response element-binding protein activity are associated with distinct postoperative behavioral changes in rats.
Li D, Ye F, Ouyang W, Wang Y
Journal of anesthesia 2017 Dec;31(6):806-812
Journal of anesthesia 2017 Dec;31(6):806-812
Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling.
Li M, Jin C, Xu M, Zhou L, Li D, Yin Y
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Cell communication and signaling : CCS 2017 Dec 16;15(1):52
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
The Effect of Hippocampal Cognitive Impairment and XIAP on Glucose and Lipids Metabolism in Rats.
Xia C, Zhu L, Shao W, Mi S, Du S, Ye L, Liu M, Pang Y, Nong L, Jiang C, Zhao H, Qi G
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;38(2):609-18
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;38(2):609-18
Activation of AMPK α2 inhibits airway smooth muscle cells proliferation.
Liu L, Pan Y, Song Y, Su X, Ke R, Yang L, Gao L, Li M
European journal of pharmacology 2016 Nov 15;791:235-243
European journal of pharmacology 2016 Nov 15;791:235-243
Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway.
Ke R, Liu L, Zhu Y, Li S, Xie X, Li F, Song Y, Yang L, Gao L, Li M
International journal of molecular sciences 2016 May 31;17(6)
International journal of molecular sciences 2016 May 31;17(6)
Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis.
Liu Q, Yuan W, Tong D, Liu G, Lan W, Zhang D, Xiao H, Zhang Y, Huang Z, Yang J, Zhang J, Jiang J
Oncotarget 2016 May 10;7(19):28235-46
Oncotarget 2016 May 10;7(19):28235-46
Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats.
Li L, Xiao L, Hou Y, He Q, Zhu J, Li Y, Wu J, Zhao J, Yu S, Zhao Y
Scientific reports 2016 Jul 25;6:30272
Scientific reports 2016 Jul 25;6:30272
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
Ye X, Zhang Y, He B, Meng Y, Li Y, Gao Y
International journal of clinical and experimental pathology 2015;8(12):15836-44
International journal of clinical and experimental pathology 2015;8(12):15836-44
AMPK interacts with DSCAM and plays an important role in netrin-1 induced neurite outgrowth.
Zhu K, Chen X, Liu J, Ye H, Zhu L, Wu JY
Protein & cell 2013 Feb;4(2):155-61
Protein & cell 2013 Feb;4(2):155-61
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10929-2-AP(PRKAA1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AMPK alpha 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AMPK alpha 1. This antibody recognizes human,mouse,rat antigen. The AMPK alpha 1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10929-2-AP(PRKAA1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue