2983

antibody from Cell Signaling Technology, Inc

Targeting: MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

2983

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#2983, RRID:AB_2105622

Product name

mTOR (7C10) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.

Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H, Cantley LC, Manning BD
Cell 2014 Feb 13;156(4):771-85

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Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.

Petit CS, Roczniak-Ferguson A, Ferguson SM
The Journal of cell biology 2013 Sep 30;202(7):1107-22

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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.

Roczniak-Ferguson A, Petit CS, Froehlich F, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM
Science signaling 2012 Jun 12;5(228):ra42

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The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.

Doberstein K, Pfeilschifter J, Gutwein P
Carcinogenesis 2011 Nov;32(11):1713-23

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.

Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM
Cancer cell 2009 Feb 3;15(2):148-59

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Photic regulation of the mTOR signaling pathway in the suprachiasmatic circadian clock.

Cao R, Lee B, Cho HY, Saklayen S, Obrietan K
Molecular and cellular neurosciences 2008 Jul;38(3):312-24