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Learn66888-1-Ig
antibody from Proteintech Group
Targeting: MTOR
FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations [0]
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- Product number
- 66888-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- mTOR antibody
- Antibody type
- Monoclonal
- Description
- mTOR antibody (Cat. #66888-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G11A3
- Vial size
- 20ul, 150ul
Submitted references Schwann cells differentiated from skin-derived precursors provide neuroprotection via autophagy inhibition in a cellular model of Parkinson's disease.
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Shexiang Baoxin Pills Inhibited Proliferation and Migration of Human Coronary Artery Smooth Muscle Cells via PI3K/AKT/mTOR Pathway.
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Morin Acts as a USP7 Inhibitor to Hold Back the Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes in a "Prickle1-mTORC2" Dependent Manner.
Anti-fatigue effects of fermented soybean protein peptides in mice.
Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Morin inhibits the transformation of fibroblasts towards myofibroblasts through regulating "PPAR-γ-glutaminolysis-DEPTOR" pathway in pulmonary fibrosis.
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Sodium butyrate ameliorates the cognitive impairment of Alzheimer's disease by regulating the metabolism of astrocytes.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea.
2-Undecanone Protects against Fine Particle-Induced Kidney Inflammation via Inducing Mitophagy.
The intestinal microbiota contributes to the growth and physiological state of muscle tissue in piglets.
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.
Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy.
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Inhibiting the Piezo1 channel protects microglia from acute hyperglycaemia damage through the JNK1 and mTOR signalling pathways.
MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways.
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Alpha-enolase (ENO1), identified as an antigen to monoclonal antibody 12C7, promotes the self-renewal and malignant phenotype of lung cancer stem cells by AMPK/mTOR pathway.
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
The probiotic effects of AB23A on high-fat-diet-induced non-alcoholic fatty liver disease in mice may be associated with suppressing the serum levels of lipopolysaccharides and branched-chain amino acids.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction.
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Knockdown of lncRNA OGFRP1 Inhibits Proliferation and Invasion of JEG-3 Cells Via AKT/mTOR Pathway.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway.
Hypothermic oxygenated machine perfusion alleviates liver injury in donation after circulatory death through activating autophagy in mice.
Yan JN, Zhang HY, Li JR, Chen Y, Jiang YC, Shen JB, Ke KF, Gu XS
Neural regeneration research 2022 Jun;17(6):1357-1363
Neural regeneration research 2022 Jun;17(6):1357-1363
FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells.
Xi H, Ren F, Li Y, Xian M, Wang L, Hu J
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Molecular and cellular endocrinology 2022 Jan 15;540:111505
Shexiang Baoxin Pills Inhibited Proliferation and Migration of Human Coronary Artery Smooth Muscle Cells via PI3K/AKT/mTOR Pathway.
Hua L, Zhou Y, Hou C, Chen J, Wang Y, Zhang S, Zhou H, He S, Jia E
Frontiers in cardiovascular medicine 2021;8:700630
Frontiers in cardiovascular medicine 2021;8:700630
Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways.
Yao M, Zhang J, Li Z, Bai X, Ma J, Li Y
Frontiers in medicine 2021;8:630962
Frontiers in medicine 2021;8:630962
Baicalein Inhibits Gastric Cancer Cell Proliferation and Migration through a FAK Interaction via AKT/mTOR Signaling.
Qiao D, Jin J, Xing J, Zhang Y, Jia N, Ren X, Lin Z, Jin N, Chen L, Piao Y
The American journal of Chinese medicine 2021;49(2):525-541
The American journal of Chinese medicine 2021;49(2):525-541
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
Yang R, Wen J, Yang T, Dai C, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosis.
Du P, Luo K, Li G, Zhu J, Xiao Q, Li Y, Zhang X
International journal of medical sciences 2021;18(15):3588-3598
International journal of medical sciences 2021;18(15):3588-3598
Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma.
Deng L, Wu X, Zhu X, Yu Z, Liu Z, Wang J, Zheng Y
American journal of translational research 2021;13(1):57-72
American journal of translational research 2021;13(1):57-72
Compound essential oils relieve oxidative stress caused by PM2 .5 exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Xian M, Cai J, Zheng K, Liu Q, Liu Y, Lin H, Liang S, Wang S
Food & function 2021 Sep 7;12(17):8056-8067
Food & function 2021 Sep 7;12(17):8056-8067
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
Morin Acts as a USP7 Inhibitor to Hold Back the Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes in a "Prickle1-mTORC2" Dependent Manner.
Yang L, Cao N, Miao Y, Dai Y, Wei Z
Molecular nutrition & food research 2021 Oct;65(19):e2100367
Molecular nutrition & food research 2021 Oct;65(19):e2100367
Anti-fatigue effects of fermented soybean protein peptides in mice.
Fang L, Zhang RX, Wei Y, Ling K, Lu L, Wang J, Pan XC, Cai MY
Journal of the science of food and agriculture 2021 Oct 25;
Journal of the science of food and agriculture 2021 Oct 25;
Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus.
Lu C, Liu X, Li J, Huang Y, Huang X, Dai G, Wu L
ACS chemical neuroscience 2021 Oct 20;12(20):3939-3946
ACS chemical neuroscience 2021 Oct 20;12(20):3939-3946
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.
Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J
Research in veterinary science 2021 Nov;140:18-25
Research in veterinary science 2021 Nov;140:18-25
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2021 Nov 29;
Environmental toxicology 2021 Nov 29;
Morin inhibits the transformation of fibroblasts towards myofibroblasts through regulating "PPAR-γ-glutaminolysis-DEPTOR" pathway in pulmonary fibrosis.
Miao Y, Geng Y, Yang L, Zheng Y, Dai Y, Wei Z
The Journal of nutritional biochemistry 2021 Nov 26;101:108923
The Journal of nutritional biochemistry 2021 Nov 26;101:108923
Morphine promotes the malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway.
Liu X, Yang J, Yang C, Huang X, Han M, Kang F, Li J
Cancer cell international 2021 Nov 25;21(1):622
Cancer cell international 2021 Nov 25;21(1):622
Sodium butyrate ameliorates the cognitive impairment of Alzheimer's disease by regulating the metabolism of astrocytes.
Wang C, Zheng D, Weng F, Jin Y, He L
Psychopharmacology 2021 Nov 23;
Psychopharmacology 2021 Nov 23;
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea.
Deng Z, Chen M, Liu Y, Xu S, Ouyang Y, Shi W, Jian D, Wang B, Liu F, Li J, Shi Q, Peng Q, Sha K, Xiao W, Liu T, Zhang Y, Zhang H, Wang Q, Sun L, Xie H, Li J
EMBO molecular medicine 2021 May 7;13(5):e13560
EMBO molecular medicine 2021 May 7;13(5):e13560
2-Undecanone Protects against Fine Particle-Induced Kidney Inflammation via Inducing Mitophagy.
Wu X, Li J, Wang S, Jiang L, Sun X, Liu X, Yao X, Zhang C, Wang N, Yang G
Journal of agricultural and food chemistry 2021 May 5;69(17):5206-5215
Journal of agricultural and food chemistry 2021 May 5;69(17):5206-5215
The intestinal microbiota contributes to the growth and physiological state of muscle tissue in piglets.
Qi R, Sun J, Qiu X, Zhang Y, Wang J, Wang Q, Huang J, Ge L, Liu Z
Scientific reports 2021 May 27;11(1):11237
Scientific reports 2021 May 27;11(1):11237
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.
Ye D, Xu H, Xia H, Zhang C, Tang Q, Bi F
Journal of experimental & clinical cancer research : CR 2021 May 18;40(1):173
Journal of experimental & clinical cancer research : CR 2021 May 18;40(1):173
Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy.
Zhu Y, Su Y, Zhang J, Zhang Y, Li Y, Han Y, Dong X, Li W, Li W
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Design, synthesis and biological evaluation of anilide (dicarboxylic acid) shikonin esters as antitumor agents through targeting PI3K/Akt/mTOR signaling pathway.
Ma Y, Yang X, Han H, Wen Z, Yang M, Zhang Y, Fu J, Wang X, Yin T, Lu G, Qi J, Lin H, Wang X, Yang Y
Bioorganic chemistry 2021 Jun;111:104872
Bioorganic chemistry 2021 Jun;111:104872
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis.
Zhang S, Lu Y, Jiang HY, Cheng ZM, Wei ZJ, Wei YH, Liu T, Xia BJ, Zhao XY, Huang Y, Zou X, Liu R, Zhou S
Cell death & disease 2021 Jun 9;12(6):597
Cell death & disease 2021 Jun 9;12(6):597
Hydrogen sulfide alleviates apoptosis and autophagy induced by beryllium sulfate in 16HBE cells.
Liu YP, Yuan XY, Li XY, Wang Y, Sun ZB, Deng WH, Lei YD, Huang L, Jiang TY, Zhang ZH
Journal of applied toxicology : JAT 2021 Jun 6;
Journal of applied toxicology : JAT 2021 Jun 6;
SNAT2/SLC38A2 Confers the Stemness of Gastric Cancer Cells via Regulating Glutamine Level.
Nie K, Cai M
Digestive diseases and sciences 2021 Jun 25;
Digestive diseases and sciences 2021 Jun 25;
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Liu C, Zhou X, Pan Y, Liu Y, Zhang Y
BMC cancer 2021 Jun 22;21(1):722
BMC cancer 2021 Jun 22;21(1):722
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
Inhibiting the Piezo1 channel protects microglia from acute hyperglycaemia damage through the JNK1 and mTOR signalling pathways.
Liu H, Bian W, Yang D, Yang M, Luo H
Life sciences 2021 Jan 1;264:118667
Life sciences 2021 Jan 1;264:118667
MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways.
Liu Z, Ma T, Duan J, Liu X, Liu L
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Zheng J, Zhu X, He Y, Hou S, Liu T, Zhi K, Hou T, Gao L
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Circ_0119872 promotes uveal melanoma development by regulating the miR-622/G3BP1 axis and downstream signalling pathways.
Liu S, Chen L, Chen H, Xu K, Peng X, Zhang M
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Journal of experimental & clinical cancer research : CR 2021 Feb 12;40(1):66
Alpha-enolase (ENO1), identified as an antigen to monoclonal antibody 12C7, promotes the self-renewal and malignant phenotype of lung cancer stem cells by AMPK/mTOR pathway.
Shu X, Cao KY, Liu HQ, Yu L, Sun LX, Yang ZH, Wu CA, Ran YL
Stem cell research & therapy 2021 Feb 12;12(1):119
Stem cell research & therapy 2021 Feb 12;12(1):119
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
So LY, Miller JE
Behavioural brain research 2021 Feb 1;398:112955
Behavioural brain research 2021 Feb 1;398:112955
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes.
Kim HJ, Han YH, Kim JY, Lee MO
Hepatology communications 2021 Dec;5(12):2121-2138
Hepatology communications 2021 Dec;5(12):2121-2138
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Acupuncture regulates the autophagy of ovarian granulosa cells in polycystic ovarian syndrome ovulation disorder by inhibiting the PI3K/AKT/mTOR pathway through LncMEG3.
Chen X, Tang H, Liang Y, Wu P, Xie L, Ding Y, Yang P, Long B, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112288
Effective-compound combination inhibits the M2-like polarization of macrophages and attenuates the development of pulmonary fibrosis by increasing autophagy through mTOR signaling.
Zhao P, Cai Z, Tian Y, Li J, Li K, Li M, Bai Y, Li J
International immunopharmacology 2021 Dec;101(Pt B):108360
International immunopharmacology 2021 Dec;101(Pt B):108360
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction.
Wang K, Li Z, Sun Y, Liu X, Ma W, Ding Y, Hong J, Qian L, Xu D
Journal of cardiovascular translational research 2021 Dec 2;
Journal of cardiovascular translational research 2021 Dec 2;
The probiotic effects of AB23A on high-fat-diet-induced non-alcoholic fatty liver disease in mice may be associated with suppressing the serum levels of lipopolysaccharides and branched-chain amino acids.
Xia F, Xiang S, Chen Z, Song L, Li Y, Liao Z, Ge B, Zhou B
Archives of biochemistry and biophysics 2021 Dec 15;714:109080
Archives of biochemistry and biophysics 2021 Dec 15;714:109080
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Xiaoli F, Yaqing Z, Ruhui L, Xuan L, Aijie C, Yanli Z, Chen H, Lili C, Longquan S
Journal of hazardous materials 2021 Aug 15;416:126158
Journal of hazardous materials 2021 Aug 15;416:126158
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Liu K, Qiu D, Liang X, Huang Y, Wang Y, Jia X, Li K, Zhao J, Du C, Qiu X, Cui J, Xiao Z, Qin Y, Zhang Q
Autophagy 2021 Aug 12;:1-17
Autophagy 2021 Aug 12;:1-17
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Ji Q, Qiao X, Liu Y, Wang D
Histology and histopathology 2021 Apr;36(4):475-484
Histology and histopathology 2021 Apr;36(4):475-484
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
Wang F, Wang L, Qu C, Chen L, Geng Y, Cheng C, Yu S, Wang D, Yang L, Meng Z, Chen Z
BMC cancer 2021 Apr 12;21(1):396
BMC cancer 2021 Apr 12;21(1):396
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625
Current drug metabolism 2020;21(8):614-625
QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagy.
Lv S, Yuan P, Dong J, Lu C, Li M, Qu F, Zhu Y, Yuan Z, Zhang J
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Journal of cellular and molecular medicine 2020 Oct;24(19):11283-11293
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Zhou X, Zhong Y, Molinar-Inglis O, Kunkel MT, Chen M, Sun T, Zhang J, Shyy JY, Trejo J, Newton AC, Zhang J
Nature communications 2020 Nov 30;11(1):6088
Nature communications 2020 Nov 30;11(1):6088
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis.
Zheng Y, Nie P, Xu S
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Journal of cellular biochemistry 2020 Jun;121(5-6):3135-3144
Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction.
Wu G, Long Y, Lu Y, Feng Y, Yang X, Xu X, Yao D
Oncology reports 2020 Jul;44(1):69-76
Oncology reports 2020 Jul;44(1):69-76
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway.
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, Qiu B, Tang B
Oncology reports 2020 Jul;44(1):103-114
Oncology reports 2020 Jul;44(1):103-114
Knockdown of lncRNA OGFRP1 Inhibits Proliferation and Invasion of JEG-3 Cells Via AKT/mTOR Pathway.
Meng Q, Xue H
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820905823
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820905823
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
Curcumin inhibits high glucose‑induced inflammatory injury in human retinal pigment epithelial cells through the ROS‑PI3K/AKT/mTOR signaling pathway.
Ran Z, Zhang Y, Wen X, Ma J
Molecular medicine reports 2019 Feb;19(2):1024-1031
Molecular medicine reports 2019 Feb;19(2):1024-1031
Hypothermic oxygenated machine perfusion alleviates liver injury in donation after circulatory death through activating autophagy in mice.
Zeng X, Wang S, Li S, Yang Y, Fang Z, Huang H, Wang Y, Fan X, Ye Q
Artificial organs 2019 Dec;43(12):E320-E332
Artificial organs 2019 Dec;43(12):E320-E332
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