Ab107045

antibody from Aladdin Scientific
Targeting: HDAC3 HD3, KDAC3, RPD3, RPD3-2
Provider product page for Ab107045

Antibody data

Product number
Ab107045 - Provider product page
Provider
Aladdin Scientific
Product name
HDAC3 Mouse mAb
Antibody type
Monoclonal
Description
Mouse anti Human HDAC3 Antibody, Monoclonal (3G3-H6-H10), could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
AA 216-422
Antibody clone number
3G3-H6-H10
Vial size
100_l,10_l,1ml,50_l
Concentration
2,9 mg/ml
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
HDAC3 protein structure - Ab107045 shown in red.