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LearnABIN358845
antibody from antibodies-online
Targeting: HSD17B10
17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN358845 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.
Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.
Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase.
Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, Trillat AC, Stern DM, Arancio O, Yan SS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 Apr;19(6):597-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 Apr;19(6):597-8
Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.
Kissinger CR, Rejto PA, Pelletier LA, Thomson JA, Showalter RE, Abreo MA, Agree CS, Margosiak S, Meng JJ, Aust RM, Vanderpool D, Li B, Tempczyk-Russell A, Villafranca JE
Journal of molecular biology 2004 Sep 17;342(3):943-52
Journal of molecular biology 2004 Sep 17;342(3):943-52
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H
Science (New York, N.Y.) 2004 Apr 16;304(5669):448-52
Science (New York, N.Y.) 2004 Apr 16;304(5669):448-52
Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.
Oppermann UC, Salim S, Tjernberg LO, Terenius L, Jörnvall H
FEBS letters 1999 May 28;451(3):238-42
FEBS letters 1999 May 28;451(3):238-42
Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase.
He XY, Merz G, Mehta P, Schulz H, Yang SY
The Journal of biological chemistry 1999 May 21;274(21):15014-9
The Journal of biological chemistry 1999 May 21;274(21):15014-9
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
