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- Product number
- ABIN393607 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 231-335) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 231-335
- Isotype
- IgG
- Antibody clone number
- 2F2
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Mechanism of oxidative stress-induced ASK1-catalyzed MKK6 phosphorylation.
Activin A induction of erythroid differentiation through MKK6-p38alpha/p38beta pathway is inhibited by follistatin.
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Activation of the p38 Map kinase pathway is essential for the antileukemic effects of dasatinib.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
Mechanism of oxidative stress-induced ASK1-catalyzed MKK6 phosphorylation.
Sturchler E, Feurstein D, McDonald P, Duckett D
Biochemistry 2010 May 18;49(19):4094-102
Biochemistry 2010 May 18;49(19):4094-102
Activin A induction of erythroid differentiation through MKK6-p38alpha/p38beta pathway is inhibited by follistatin.
Huang HM, Li YC, Chung MH
Journal of cellular physiology 2010 Jun;223(3):687-94
Journal of cellular physiology 2010 Jun;223(3):687-94
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators., NORDIL investigators., BRIGHT Consortium.
American journal of human genetics 2009 Nov;85(5):628-42
American journal of human genetics 2009 Nov;85(5):628-42
Activation of the p38 Map kinase pathway is essential for the antileukemic effects of dasatinib.
Dumka D, Puri P, Carayol N, Lumby C, Balachandran H, Schuster K, Verma AK, Terada LS, Platanias LC, Parmar S
Leukemia & lymphoma 2009 Dec;50(12):2017-29
Leukemia & lymphoma 2009 Dec;50(12):2017-29
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- Submitted by
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- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
