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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- 604702 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#604702, RRID:AB_2141554
- Product name
- Purified anti-MKK6
- Antibody type
- Polyclonal
- Antigen
- Recombinant (partial) , N-terminal
- Description
- MKK6 (Mitogen-activated protein kinase 6, MAPK/ERK kinase 6) is a 37 kD serine/threonine kinase family, MAP kinase subfamily. Two isoforms of MKK6 have been reported; MKK6 (only heart), MKK6B muscle, heart, liver, and pancreas. MKK6 phosphorylates and activates MAP kinase p38 and stress-activated kinase JNK. MKK6 is activated by UV, anisomycin, and osomotic shock. MKK6 is phosphorylated (Ser 207/Thr 211). MKK6 has been shown to interact with ASK-1 kinase. The Poly6047 antibody recognizes the N-terminal region of both human and mouse MKK6 and has been shown to be useful for Western blotting.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- Upon receipt, store frozen at -20° C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Jurkat cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with rabbit anti-MKK6 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system.
- Conjugate
- Unconjugated
