Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB11252 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB11252, RRID:AB_1671641
- Product name
- BBC3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to C-terminus of human BBC3.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals.
PUMA, a novel proapoptotic gene, is induced by p53.
PUMA induces the rapid apoptosis of colorectal cancer cells.
Han J, Flemington C, Houghton AB, Gu Z, Zambetti GP, Lutz RJ, Zhu L, Chittenden T
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11318-23
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11318-23
PUMA, a novel proapoptotic gene, is induced by p53.
Nakano K, Vousden KH
Molecular cell 2001 Mar;7(3):683-94
Molecular cell 2001 Mar;7(3):683-94
PUMA induces the rapid apoptosis of colorectal cancer cells.
Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B
Molecular cell 2001 Mar;7(3):673-82
Molecular cell 2001 Mar;7(3):673-82
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BBC3 expression in human K-562 (lane 1) and mouse NIH/3T3 (lane 2) cell lysates with BBC3 polyclonal antibody (Cat # PAB11252) at 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunocytochemistry of BBC3 in K-562 cells with BBC3 polyclonal antibody (Cat # PAB11252) at 1 ug/mL .
- Validation comment
- Immunocytochemistry