Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS4770 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Rel B (phospho S552) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic phosphopeptide derived from human Rel B around the phosphorylation site of Serine 552.
- Description
- The NF°ÙB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NF°ÙB subunit. Rel B does not bind with high affinity to NF°ÙB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NF°ÙB homodimers. However, Rel B/p50 heterodimers, in contrast to NF°ÙB heterodimers, transactivates transcription of promotors containing °ÙB binding sites.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of p-Rel B (S552) pAb at 1:500 dilutionLane1:Hela cell lysate treated with TNFaLane2:Mouse stomach tissue lysateLane3:Mouse colon tissuel lysateLane4:Rat colon tissue lysate