MB0070

antibody from Bioworld Technology, Inc

Targeting: ACLY ACL, ATPCL, CLATP

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Validation data

Product number: MB0070 - Provider product page
Provider: Bioworld Technology, Inc
Product name: ATP Citrate Lyase (C terminus) monoclonal antibody
Antibody type: Monoclonal
Antigen: Synthetic peptide, corresponding to amino acids C-terminus of Human ATP-Citrate Lyase.
Description: ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of four identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. One of these products, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. NDPK has been found to phosphorylate ACL and insulin to increase phosphorylation of ACL.
Reactivity: Human
Host: Mouse
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ACLY protein structure - MB0070 shown in red.