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- Antibody Data
- Antigen structure
- References [1]
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- Product number
- PA1-28361 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Serum Amyloid P Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Purifed from natural sources
- Description
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 500 µL
- Concentration
- 0.49 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits.
Larsen CP, Sharma SG, Caza TN, Kenan DJ, Storey AJ, Edmondson RD, Herzog C, Arthur JM
Kidney international 2020 Mar;97(3):602-608
Kidney international 2020 Mar;97(3):602-608
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2 | Colocalization of IgG and serum amyloid P-component (SAP). (a-c) Immunofluorescence experiments performed on a renal biopsy sample from a patient diagnosed with membranous-like glomerulopathy with masked IgG kappa deposits shows granular glomerular basement membrane staining for (a) SAP and (b) IgG. (c) There is strong colocalization of SAP and IgG in the glomerular basement membrane deposits. (d-f) Immunofluorescence experiments performed on a renal biopsy sample from a patient with 3 phospholipase A2 receptor- positive membranous glomerulopathies shows (d) negative glomerular basement membrane staining for SAP and (e) positive granular glomerular basement membrane staining for IgG. (f) There is lack of colocalization in this patient with 3 phospholipase A2 receptor-associated membranous glomerulopathies. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org .
