GTX110704

antibody from GeneTex

Targeting: CAT

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX110704

Provider

GeneTex

Proper citation

GeneTex Cat#GTX110704, RRID:AB_1949848

Product name

Catalase antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat

Host

Rabbit

References

Submitted references

Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions.

Hyatt HW, Zhang Y, Hood WR, Kavazis AN
Reproductive sciences (Thousand Oaks, Calif.) 2019 Jan;26(1):114-127

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Increased SOD2 in the diaphragm contributes to exercise-induced protection against ventilator-induced diaphragm dysfunction.

Morton AB, Smuder AJ, Wiggs MP, Hall SE, Ahn B, Hinkley JM, Ichinoseki-Sekine N, Huertas AM, Ozdemir M, Yoshihara T, Wawrzyniak NR, Powers SK
Redox biology 2019 Jan;20:402-413

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1,25-Dihydroxyvitamin D₃ modulates the effects of sublethal BPA on mitochondrial function via activating PI3K-Akt pathway and 17β-estradiol secretion in rat granulosa cells.

Lee CT, Wang JY, Chou KY, Hsu MI
The Journal of steroid biochemistry and molecular biology 2019 Jan;185:200-211

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Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress.

Wu CC, Lee PT, Kao TJ, Chou SY, Su RY, Lee YC, Yeh SH, Liou JP, Hsu TI, Su TP, Chuang CK, Chang WC, Chuang JY
Redox biology 2018 Oct;19:74-80

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A mitohormetic response to pro-oxidant exposure in the house mouse.

Zhang Y, Humes F, Almond G, Kavazis AN, Hood WR
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jan 1;314(1):R122-R134

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Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway.

Wu YL, Chang JC, Lin WY, Li CC, Hsieh M, Chen HW, Wang TS, Wu WT, Liu CS, Liu KL
Free radical biology & medicine 2018 Feb 1;115:309-317

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High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis.

Zhang Y, Brasher AL, Park NR, Taylor HA, Kavazis AN, Hood WR
The Journal of experimental biology 2018 Apr 6;221(Pt 7)

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3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.

Chao W, Deng JS, Huang SS, Li PY, Liang YC, Huang GJ
International immunopharmacology 2017 Sep;50:77-86

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The 1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt Supplementation on Multi-Organ Markers of Oxidative Stress and Mitochondrial Function in Rats.

Kephart WC, Mumford PW, Mao X, Romero MA, Hyatt HW, Zhang Y, Mobley CB, Quindry JC, Young KC, Beck DT, Martin JS, McCullough DJ, D'Agostino DP, Lowery RP, Wilson JM, Kavazis AN, Roberts MD
Nutrients 2017 Sep 15;9(9)

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High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.

Noguera NI, Pelosi E, Angelini DF, Piredda ML, Guerrera G, Piras E, Battistini L, Massai L, Berardi A, Catalano G, Cicconi L, Castelli G, D'Angiò A, Pasquini L, Graziani G, Fioritoni G, Voso MT, Mastrangelo D, Testa U, Lo-Coco F
Oncotarget 2017 May 16;8(20):32550-32565

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3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.

Chao W, Deng JS, Li PY, Liang YC, Huang GJ
Molecules (Basel, Switzerland) 2017 Mar 28;22(4)

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Concomitant external pneumatic compression treatment with consecutive days of high intensity interval training reduces markers of proteolysis.

Haun CT, Roberts MD, Romero MA, Osburn SC, Healy JC, Moore AN, Mobley CB, Roberson PA, Kephart WC, Mumford PW, Goodlett MD, Pascoe DD, Martin JS
European journal of applied physiology 2017 Dec;117(12):2587-2600

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Lactation has persistent effects on a mother's metabolism and mitochondrial function.

Hyatt HW, Zhang Y, Hood WR, Kavazis AN
Scientific reports 2017 Dec 7;7(1):17118

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Comparative changes in antioxidant enzymes and oxidative stress in cardiac, fast twitch and slow twitch skeletal muscles following endurance exercise training.

Hyatt HW, Smuder AJ, Sollanek KJ, Morton AB, Roberts MD, Kavazis AN
International journal of physiology, pathophysiology and pharmacology 2016;8(4):160-168

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A Ketogenic Diet in Rodents Elicits Improved Mitochondrial Adaptations in Response to Resistance Exercise Training Compared to an Isocaloric Western Diet.

Hyatt HW, Kephart WC, Holland AM, Mumford P, Mobley CB, Lowery RP, Roberts MD, Wilson JM, Kavazis AN
Frontiers in physiology 2016;7:533

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Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice.

Mowry AV, Kavazis AN, Sirman AE, Potts WK, Hood WR
PloS one 2016;11(8):e0160883

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Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle.

Martin JS, Kephart WC, Haun CT, McCloskey AE, Shake JJ, Mobley CB, Goodlett MD, Kavazis A, Pascoe DD, Zhang L, Roberts MD
Physiological reports 2016 Nov;4(22)

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Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells.

Xu YM, Wu DD, Zheng W, Yu FY, Yang F, Yao Y, Zhou Y, Ching YP, Lau AT
Oncotarget 2016 Feb 2;7(5):6146-58

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Selenite and ebselen supplementation attenuates D-galactose-induced oxidative stress and increases expression of SELR and SEP15 in rat lens.

Dai J, Zhou J, Liu H, Huang K
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2016 Dec;21(8):1037-1046

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Influence of endurance exercise training on antioxidant enzymes, tight junction proteins, and inflammatory markers in the rat ileum.

Holland AM, Hyatt HW, Smuder AJ, Sollanek KJ, Morton AB, Roberts MD, Kavazis AN
BMC research notes 2015 Sep 30;8:514

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Comparative adaptations in oxidative and glycolytic muscle fibers in a low voluntary wheel running rat model performing three levels of physical activity.

Hyatt HW, Toedebusch RG, Ruegsegger G, Mobley CB, Fox CD, McGinnis GR, Quindry JC, Booth FW, Roberts MD, Kavazis AN
Physiological reports 2015 Nov;3(11)

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Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.

Wu CH, Tang SC, Wang PH, Lee H, Ko JL
The Journal of biological chemistry 2012 Jul 20;287(30):25292-302

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Sample (30 ug of whole cell lysate) A: HepG2 7.5% SDS PAGE GTX110704 diluted at 1:1000

Validation comment

WB

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Sample (30 ?g of whole cell lysate) A: Neuro2A B: GL261 C: C8D30 7.5% SDS PAGE GTX110704 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Sample (50 ?g of whole cell lysate) A: Rat kidney 7.5% SDS PAGE GTX110704 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Rat tissue extract (50 ?g) was separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Mouse tissue extract (50 ?g) was separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:3000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Rat tissue extract (50 ?g) was separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Mouse tissue extract (50 ?g) was separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:3000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with Catalase antibody (GTX110704) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Catalase (GTX110704) antibody at 1:500 dilution.