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- Antigen structure
- References [6]
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- Validations
- Immunocytochemistry [2]
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- Product number
- ADI-AAP-330-E - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-AAP-330-E, RRID:AB_2038875
- Product name
- Bim/BOD polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Peptide affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- +4°C
Submitted references An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo.
Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim.
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.
An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins.
Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death.
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis.
Aubrey BJ, Kelly GL, Kueh AJ, Brennan MS, O'Connor L, Milla L, Wilcox S, Tai L, Strasser A, Herold MJ
Cell reports 2015 Mar 3;10(8):1422-32
Cell reports 2015 Mar 3;10(8):1422-32
Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim.
Szegezdi E, Herbert KR, Kavanagh ET, Samali A, Gorman AM
Journal of cellular and molecular medicine 2008 Dec;12(6A):2482-96
Journal of cellular and molecular medicine 2008 Dec;12(6A):2482-96
TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.
Koschny R, Ganten TM, Sykora J, Haas TL, Sprick MR, Kolb A, Stremmel W, Walczak H
Hepatology (Baltimore, Md.) 2007 Mar;45(3):649-58
Hepatology (Baltimore, Md.) 2007 Mar;45(3):649-58
An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from D-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins.
Takamura M, Matsuda Y, Yamagiwa S, Tamura Y, Honda Y, Suzuki K, Ichida T, Aoyagi Y
Life sciences 2007 Mar 13;80(14):1335-44
Life sciences 2007 Mar 13;80(14):1335-44
Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death.
Straub JA, Lipscomb EA, Yoshida ES, Freeman RS
Journal of neurochemistry 2003 Apr;85(2):318-28
Journal of neurochemistry 2003 Apr;85(2):318-28
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis.
Putcha GV, Moulder KL, Golden JP, Bouillet P, Adams JA, Strasser A, Johnson EM
Neuron 2001 Mar;29(3):615-28
Neuron 2001 Mar;29(3):615-28
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of human K562 cell lysate probed with Bim/BOD, pAb.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of Bim in human skin cancer cells with Bim antibody at 20µg/ml.
