Antibody data
- Antibody Data
- Antigen structure
- References [238]
- Comments [0]
- Validations
- Western blot [10]
- Immunocytochemistry [2]
- Immunohistochemistry [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- GTX109639 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX109639, RRID:AB_1949572
- Product name
- beta Actin antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Canine, Drosophila, Feline, Hamster, Horse, Porcine, Xenopus, Yeast
- Host
- Rabbit
Submitted references Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms.
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation.
Ampelopsins A and C Induce Apoptosis and Metastasis through Downregulating AxL, TYRO3, and FYN Expressions in MDA-MB-231 Breast Cancer Cells.
Induction of Mitotic Catastrophe via Inhibition of Aurora B by Ionizing Radiation With Additive of Mulberry Water Extract in Human Bladder Cancer Cells.
Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.
Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.
Osteopontin Protects Colonic Mucosa from Dextran Sodium Sulfate-Induced Acute Colitis in Mice by Regulating Junctional Distribution of Occludin.
CXCR7 promotes melanoma tumorigenesis via Src kinase signaling.
Effect of mild hypothermia on cerebral microcirculation in a murine cardiopulmonary resuscitation model.
Melatonin Inhibits in Vitro Smooth Muscle Cell Inflammation and Proliferation and Atherosclerosis in Apolipoprotein E-Deficient Mice.
Pigment epithelium-derived factor inhibits lung cancer migration and invasion by upregulating exosomal thrombospondin 1.
Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species.
Preprogramming therapeutic response of PI3K/mTOR dual inhibitor via the regulation of EHMT2 and p27 in pancreatic cancer.
Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression.
Reduction of Thermotolerance by Heat Shock Protein 90 Inhibitors in Murine Erythroleukemia Cells.
DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling.
Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells.
Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells.
Sodium Iodate Disrupted the Mitochondrial-Lysosomal Axis in Cultured Retinal Pigment Epithelial Cells.
The Physicochemical Properties of Decellularized Extracellular Matrix-Coated 3D Printed Poly(ε-caprolactone) Nerve Conduits for Promoting Schwann Cells Proliferation and Differentiation.
Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells.
Mineral Trioxide Aggregate Mixed with 5-Aminolevulinic Acid for the Photodynamic Antimicrobial Strategy in Hard Tissue Regeneration.
Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction.
Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair.
MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.
A Faroese founder variant in TBCD causes early onset, progressive encephalopathy with a homogenous clinical course.
ICR suckling mouse model of Zika virus infection for disease modeling and drug validation.
Effects of bone morphogenic protein-2 loaded on the 3D-printed MesoCS scaffolds.
Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer.
Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target.
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation.
Differential regulation of MyD88- and TRIF-dependent signaling pathways of Toll-like receptors by cardamonin.
A high-throughput pipeline for validation of antibodies.
Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation.
The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo.
Caveolin-1 down-regulation is required for Wnt5a-Frizzled 2 signalling in Ha-RasV12 -induced cell transformation.
cDNA Microarray Analysis and Influx Transporter OATP1B1 in Liver Cells After Exposure to Gadoxetate Disodium, a Gadolinium-based Contrast Agent in MRI Liver Imaging.
Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair.
AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling.
Extrahepatic angiogenesis hinders recovery of portal hypertension and collaterals in rats with cirrhosis resolution.
EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma.
Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling.
Ghrelin ameliorates acute lung injury induced by oleic acid via inhibition of endoplasmic reticulum stress.
The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation.
Scutellaria baicalensis regulates FFA metabolism to ameliorate NAFLD through the AMPK-mediated SREBP signaling pathway.
Posttranslational regulation of CYP2J2 by nitric oxide.
Changes in plasma 5-HT levels and equine leukocyte SERT expression in response to treadmill exercise.
ER stress attenuation by Aloe-derived polysaccharides in the protection of pancreatic β-cells from free fatty acid-induced lipotoxicity.
The Potential of Brown Adipogenesis and Browning in Porcine Bone Marrow-derived Mesenchymal Stem Cells.
ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts.
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.
Role of the ERp57 protein (1,25D3-MARRS receptor) in murine mammary gland growth and development.
Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.
Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors.
Rehydration with fructose worsens dehydration-induced renal damage.
Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus.
ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.
Global chondrocyte gene expression after a single anabolic loading period: Time evolution and re-inducibility of mechano-responses.
MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.
MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.
Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis.
LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells.
Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis.
Effects of the RNA-binding protein, KSRP, on innate immune response against Helicobacter pylori infection in mice.
Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5.
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity.
Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress.
Pleurotus sajor-caju can be used to synthesize silver nanoparticles with antifungal activity against Candida albicans.
miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-PI3K/AKT/mTOR Signaling Pathway.
PP2A deactivation is a common event in oral cancer and reactivation by FTY720 shows promising therapeutic potential.
Proteomic Profiling of Brain and Testis Reveals the Diverse Changes in Ribosomal Proteins in fmr1 Knockout Mice.
ΔNp63 promotes abnormal epidermal proliferation in arsenical skin cancers.
Early intervention of N-acetylcysteine better improves insulin resistance in diet-induced obesity mice.
Chemical composition and biological activity of extracts from fruiting bodies and mycelial cultures of Fomitopsis betulina.
Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts.
Inhibition of autophagy by chloroquine makes chemotherapy in nasopharyngeal carcinoma more efficient.
miR-4725-3p targeting stromal interacting molecule 1 signaling is involved in xanthohumol inhibition of glioma cell invasion.
Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.
Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia.
Inhibitory effects of selenium on cadmium-induced cytotoxicity in PC12 cells via regulating oxidative stress and apoptosis.
Development of a computational promoter with highly efficient expression in tumors.
Anti-inflammatory activities of garlic sprouts, a source of α-linolenic acid and 5-hydroxy-l-tryptophan, in RAW 264.7 cells.
Uncovering the Molecular Mechanism of Anti-Allergic Activity of Silkworm Pupa-Grown Cordyceps militaris Fruit Body.
9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1, 2-c]quinolin-11-one (BPIQ), A Quinoline Derivative Inhibits Human Hepatocellular Carcinoma Cells by Inducing ER Stress and Apoptosis.
Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.
The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA.
Detection and quantification of dengue virus using a novel biosensor system based on dengue NS3 protease activity.
The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice.
The Impact of MicroRNA-223-3p on IL-17 Receptor D Expression in Synovial Cells.
Torenia concolor Lindley var. formosana Yamazaki extracts improve inflammatory response and lipid accumulation via PPARs activation.
3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.
G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells.
Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement.
The Beneficial Effects of Allicin in Chronic Kidney Disease Are Comparable to Losartan.
Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells.
The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer.
A novel function of neuroglobin for neuroregeneration in mice after optic nerve injury.
Long noncoding RNA MIAT promotes non-small cell lung cancer proliferation and metastasis through MMP9 activation.
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers.
Cytotoxic effects of cadmium and zinc co-exposure in PC12 cells and the underlying mechanism.
Metabolic adaptation via regulated enzyme degradation in the pathogenic yeast Candida albicans.
Molecular mechanisms of the effects of the ethanolic extract of Muntingia calabura Linn. fruit on lipopolysaccharide-induced pro-inflammatory mediators in macrophages.
Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth.
Inhibitory effects of rosmarinic acid on pterygium epithelial cells through redox imbalance and induction of extrinsic and intrinsic apoptosis.
Yeast Cip1 is activated by environmental stress to inhibit Cdk1-G1 cyclins via Mcm1 and Msn2/4.
Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells.
Epigenetic regulation of the glucose transporter gene Slc2a1 by β-hydroxybutyrate underlies preferential glucose supply to the brain of fasted mice.
Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila.
Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells.
Therapeutic vaccine targeting Epstein-Barr virus latent protein, LMP1, suppresses LMP1-expressing tumor growth and metastasis in vivo.
Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.
Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro.
Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer.
Effects of exosome-like vesicles on cumulus expansion in pigs in vitro.
Apolipoprotein M Inhibits Angiogenic and Inflammatory Response by Sphingosine 1-Phosphate on Retinal Pigment Epithelium Cells.
Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma.
KH-type splicing regulatory protein mediate inflammatory response in gastric epithelial cells induced by lipopolysaccharide.
Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells.
Electroacupuncture Promotes Recovery of Motor Function and Reduces Dopaminergic Neuron Degeneration in Rodent Models of Parkinson's Disease.
SHP-2 phosphatase controls aryl hydrocarbon receptor-mediated ER stress response in mast cells.
The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity.
Separation of photoreceptor cell compartments in mouse retina for protein analysis.
Induction of cyclooxygenase-2 gene by Candida albicans through EGFR, ERK, and p38 pathways in human urinary epithelium.
Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis.
EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells.
Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma.
The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages.
Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure.
Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.
Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning.
The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
The contribution of toll-like receptor 2 on Helicobacter pylori activation of the nuclear factor-kappa B signaling pathway in gastric epithelial cells.
CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL).
Resolvin D1 down-regulates CYP1A1 and PTGS2 gene in the HUVEC cells treated with benzo(a)pyrene.
Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing.
MicroRNA-214 exerts a Cardio-protective effect by inhibition of fibrosis.
The effects of cytotoxic necrotizing factor 1 expression in the uptake of Escherichia coli K1 by macrophages and the onset of meningitis in newborn mice.
In vitro cultures of Bacopa monnieri and an analysis of selected groups of biologically active metabolites in their biomass.
Redistribution of Cav2.1 channels and calcium ions in nerve terminals following end-to-side neurorrhaphy: ionic imaging analysis by TOF-SIMS.
Corrosion-Activated Chemotherapeutic Function of Nanoparticulate Platinum as a Cisplatin Resistance-Overcoming Prodrug with Limited Autophagy Induction.
The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death.
WITHDRAWN: Decreased level of endogenous ghrelin is involved in the progression of lung injury induced by oleic acid.
The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice.
A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA.
Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways.
MicroRNA let-7b induces lens epithelial cell apoptosis by targeting leucine-rich repeat containing G protein-coupled receptor 4 (Lgr4) in age-related cataract.
Duodenojejunal Bypass Leads to Altered Gut Microbiota and Strengthened Epithelial Barriers in Rats.
Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells.
Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.
Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells.
Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo.
Tanshinone IIA ameliorates apoptosis of cardiomyocytes induced by endoplasmic reticulum stress.
Inhibition of cytoskeletal protein carbonylation may protect against oxidative damage in traumatic brain injury.
The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-κB signaling pathway.
Hepatocarcinogenesis in transgenic mice carrying hepatitis B virus pre-S/S gene with the sW172* mutation.
miRNA-342 Regulates CEACAM1-induced Lumen Formation in a Three-dimensional Model of Mammary Gland Morphogenesis.
Induction of Lumen Formation in a Three-dimensional Model of Mammary Morphogenesis by Transcriptional Regulator ID4: ROLE OF CaMK2D IN THE EPIGENETIC REGULATION OF ID4 GENE EXPRESSION.
DEF6 expression in ovarian carcinoma correlates with poor patient survival.
Mouse oocytes suppress miR-322-5p expression in ovarian granulosa cells.
Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor.
Anti-IL-20 monoclonal antibody promotes bone fracture healing through regulating IL-20-mediated osteoblastogenesis.
Possible production of arsenic hemoglobin adducts via exposure to arsine.
Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo.
Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo.
Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells.
Effects of oral phosphatidic acid feeding with or without whey protein on muscle protein synthesis and anabolic signaling in rodent skeletal muscle.
Effects of protein type and composition on postprandial markers of skeletal muscle anabolism, adipose tissue lipolysis, and hypothalamic gene expression.
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Cleavage of Dicer protein by I7 protease during vaccinia virus infection.
Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells.
Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy.
Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival.
Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.
CTRP3 acts as a negative regulator of osteoclastogenesis through AMPK-c-Fos-NFATc1 signaling in vitro and RANKL-induced calvarial bone destruction in vivo.
Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells.
MicroRNA-302b Enhances the Sensitivity of Hepatocellular Carcinoma Cell Lines to 5-FU via Targeting Mcl-1 and DPYD.
Low-dose Bisphenol A Activates Cyp11a1 Gene Expression and Corticosterone Secretion in Adrenal Gland via the JNK Signaling Pathway.
B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.
Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.
Three Pathways Assess Anti-Inflammatory Response of Epicatechin with Lipopolysaccharide-Mediated Macrophage RAW264.7 Cells
N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting.
Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.
Identification of the full-length β-actin sequence and expression profiles in the tree shrew (Tupaia belangeri).
S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells.
Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells.
PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells.
Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines.
Impact of maternal n-3 polyunsaturated fatty acid deficiency on dendritic arbor morphology and connectivity of developing Xenopus laevis central neurons in vivo.
Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes.
The untranslated regions of classic swine fever virus RNA trigger apoptosis.
Growth inhibition of head and neck squamous cell carcinoma cells by sgRNA targeting the cyclin D1 mRNA based on TRUE gene silencing.
One-step generation of phenotype-expressing triple-knockout mice with heritable mutated alleles by the CRISPR/Cas9 system.
Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest.
Pre-conditioning with CDP-choline attenuates oxidative stress-induced cardiac myocyte death in a hypoxia/reperfusion model.
A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.
TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Nuclear proteomics with XRCC3 knockdown to reveal the development of doxorubicin-resistant uterine cancer.
TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage.
Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.
Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells.
Expression of lysophosphatidic acid receptors in the human lower esophageal sphincter.
Tumor necrosis factor suppresses NR5A2 activity and intestinal glucocorticoid synthesis to sustain chronic colitis.
The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression.
MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis.
Nitric oxide plays a dual role in the oxidative injury of cultured rat microglia but not astroglia.
Deactivation of TBP contributes to SCA17 pathogenesis.
Identification of a membrane-targeting domain of the transient receptor potential canonical (TRPC)4 channel unrelated to its formation of a tetrameric structure.
PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells.
Proliferative effects of melatonin on Schwann cells: implication for nerve regeneration following peripheral nerve injury.
Oligomerization-induced conformational change in the C-terminal region of Nel-like molecule 1 (NELL1) protein is necessary for the efficient mediation of murine MC3T3-E1 cell adhesion and spreading.
Inhibitory effect of litchi (Litchi chinensis Sonn.) flower on lipopolysaccharide-induced expression of proinflammatory mediators in RAW264.7 cells through NF-κB, ERK, and JAK2/STAT3 inactivation.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Polysaccharides Reduce Lipopolysaccharide-Induced Interleukin-1 Expression in Cultured Smooth Muscle Cells and in Thoracic Aortas in Mice
HIF1-α-mediated gene expression induced by vitamin B1 deficiency.
2-methoxyestradiol induces mitotic arrest, apoptosis, and synergistic cytotoxicity with arsenic trioxide in human urothelial carcinoma cells.
HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?
MicroRNA-449a enhances radiosensitivity in CL1-0 lung adenocarcinoma cells.
Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo.
Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents.
Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease.
High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease.
Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.
Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.
The synthetic flavonoid WYC02-9 inhibits colorectal cancer cell growth through ROS-mediated activation of MAPK14 pathway.
Proteomic analysis of retinopathy-related plasma biomarkers in diabetic patients.
Postoperative impairment of cognitive function in old mice: a possible role for neuroinflammation mediated by HMGB1, S100B, and RAGE.
Evaluation of arginine deiminase treatment in melanoma xenografts using (18)F-FLT PET.
The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling.
Effects of cadmium chloride on the cultured human lens epithelial cells.
Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer.
p38 mitogen-activated protein kinase and PI3-kinase are involved in up-regulation of mu opioid receptor transcription induced by cycloheximide.
Id1 promotes lung cancer cell proliferation and tumor growth through Akt-related pathway.
Wei CL, Wang S, Yen JT, Cheng YF, Liao CL, Hsu CC, Wu CC, Tsai YC
Brain research 2019 May 15;1711:202-213
Brain research 2019 May 15;1711:202-213
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen Y, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K
Nature 2019 Mar;567(7746):118-122
Nature 2019 Mar;567(7746):118-122
Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation.
Hsu FF, Chou YT, Chiang MT, Li FA, Yeh CT, Lee WH, Chau LY
Oncogene 2019 Mar;38(10):1688-1701
Oncogene 2019 Mar;38(10):1688-1701
Ampelopsins A and C Induce Apoptosis and Metastasis through Downregulating AxL, TYRO3, and FYN Expressions in MDA-MB-231 Breast Cancer Cells.
Huang C, Huang YL, Wang CC, Pan YL, Lai YH, Huang HC
Journal of agricultural and food chemistry 2019 Mar 13;67(10):2818-2830
Journal of agricultural and food chemistry 2019 Mar 13;67(10):2818-2830
Induction of Mitotic Catastrophe via Inhibition of Aurora B by Ionizing Radiation With Additive of Mulberry Water Extract in Human Bladder Cancer Cells.
Su CC, Chen NC, Chyau CC, Tseng HC, Chou FP
Integrative cancer therapies 2019 Jan-Dec;18:1534735418808586
Integrative cancer therapies 2019 Jan-Dec;18:1534735418808586
Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.
Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K
The Journal of clinical investigation 2019 Jan 2;129(1):281-295
The Journal of clinical investigation 2019 Jan 2;129(1):281-295
Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.
Tsai YF, Yang DJ, Ngo TH, Shih CH, Wu YF, Lee CK, Phraekanjanavichid V, Yen SF, Kao SH, Lee HM, Huang VS, Shieh JC, Lin YF
ACS chemical neuroscience 2019 Jan 16;10(1):528-536
ACS chemical neuroscience 2019 Jan 16;10(1):528-536
Osteopontin Protects Colonic Mucosa from Dextran Sodium Sulfate-Induced Acute Colitis in Mice by Regulating Junctional Distribution of Occludin.
Woo SH, Lee SH, Park JW, Go DM, Kim DY
Digestive diseases and sciences 2019 Feb;64(2):421-431
Digestive diseases and sciences 2019 Feb;64(2):421-431
CXCR7 promotes melanoma tumorigenesis via Src kinase signaling.
Xu S, Tang J, Wang C, Liu J, Fu Y, Luo Y
Cell death & disease 2019 Feb 25;10(3):191
Cell death & disease 2019 Feb 25;10(3):191
Effect of mild hypothermia on cerebral microcirculation in a murine cardiopulmonary resuscitation model.
Yu H, Wang L, Zhang H, Wei W, Chen Y, Tang W, Wan Z
Microcirculation (New York, N.Y. : 1994) 2019 Feb 23;
Microcirculation (New York, N.Y. : 1994) 2019 Feb 23;
Melatonin Inhibits in Vitro Smooth Muscle Cell Inflammation and Proliferation and Atherosclerosis in Apolipoprotein E-Deficient Mice.
Li HY, Leu YL, Wu YC, Wang SH
Journal of agricultural and food chemistry 2019 Feb 20;67(7):1889-1901
Journal of agricultural and food chemistry 2019 Feb 20;67(7):1889-1901
Pigment epithelium-derived factor inhibits lung cancer migration and invasion by upregulating exosomal thrombospondin 1.
Huang WT, Chong IW, Chen HL, Li CY, Hsieh CC, Kuo HF, Chang CY, Chen YH, Liu YP, Lu CY, Liu YR, Liu PL
Cancer letters 2019 Feb 1;442:287-298
Cancer letters 2019 Feb 1;442:287-298
Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species.
Lee CW, Chi MC, Chang TM, Liu JF
Journal of cellular physiology 2019 Aug;234(8):13157-13168
Journal of cellular physiology 2019 Aug;234(8):13157-13168
Preprogramming therapeutic response of PI3K/mTOR dual inhibitor via the regulation of EHMT2 and p27 in pancreatic cancer.
Tian YF, Wang HC, Luo CW, Hung WC, Lin YH, Chen TY, Li CF, Lin CY, Pan MR
American journal of cancer research 2018;8(9):1812-1822
American journal of cancer research 2018;8(9):1812-1822
Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression.
Chen HY, Huang TC, Lin LC, Shieh TM, Wu CH, Wang KL, Hong YH, Hsia SM
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(5):1970-1986
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(5):1970-1986
Reduction of Thermotolerance by Heat Shock Protein 90 Inhibitors in Murine Erythroleukemia Cells.
Uehara Y, Temma K, Kobayashi Y, Irie N, Yamaguchi T
Biological & pharmaceutical bulletin 2018;41(9):1393-1400
Biological & pharmaceutical bulletin 2018;41(9):1393-1400
DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling.
Liao WC, Liao CK, Tsai YH, Tseng TJ, Chuang LC, Lan CT, Chang HM, Liu CH
PloS one 2018;13(6):e0198364
PloS one 2018;13(6):e0198364
Enhanced anticancer effects of low-dose curcumin with non-invasive pulsed electric field on PANC-1 cells.
Lu CH, Lin SH, Hsieh CH, Chen WT, Chao CY
OncoTargets and therapy 2018;11:4723-4732
OncoTargets and therapy 2018;11:4723-4732
Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells.
Lee CF, Chiang NN, Lu YH, Huang YS, Yang JS, Tsai SC, Lu CC, Chen FA
BioMedicine 2018 Sep;8(3):15
BioMedicine 2018 Sep;8(3):15
Sodium Iodate Disrupted the Mitochondrial-Lysosomal Axis in Cultured Retinal Pigment Epithelial Cells.
Lin YC, Horng LY, Sung HC, Wu RT
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2018 Sep;34(7):500-511
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2018 Sep;34(7):500-511
The Physicochemical Properties of Decellularized Extracellular Matrix-Coated 3D Printed Poly(ε-caprolactone) Nerve Conduits for Promoting Schwann Cells Proliferation and Differentiation.
Chen CC, Yu J, Ng HY, Lee AK, Chen CC, Chen YS, Shie MY
Materials (Basel, Switzerland) 2018 Sep 9;11(9)
Materials (Basel, Switzerland) 2018 Sep 9;11(9)
Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells.
Hsu HY, Lin TY, Hu CH, Shu DTF, Lu MK
Cancer letters 2018 Sep 28;432:112-120
Cancer letters 2018 Sep 28;432:112-120
Mineral Trioxide Aggregate Mixed with 5-Aminolevulinic Acid for the Photodynamic Antimicrobial Strategy in Hard Tissue Regeneration.
Shen YF, Huang TH, Ng HY, Fang HY, Hsu TT
Materials (Basel, Switzerland) 2018 Sep 14;11(9)
Materials (Basel, Switzerland) 2018 Sep 14;11(9)
Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction.
Wang TH, Hsueh C, Chen CC, Li WS, Yeh CT, Lian JH, Chang JL, Chen CY
International journal of molecular sciences 2018 Sep 10;19(9)
International journal of molecular sciences 2018 Sep 10;19(9)
Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair.
Chen CC, Chen CY, Wang SH, Yeh CT, Su SC, Ueng SH, Chuang WY, Hsueh C, Wang TH
Cancers 2018 Sep 10;10(9)
Cancers 2018 Sep 10;10(9)
MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.
Hou HH, Wang HC, Cheng SL, Chen YF, Lu KZ, Yu CJ
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L432-L442
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L432-L442
A Faroese founder variant in TBCD causes early onset, progressive encephalopathy with a homogenous clinical course.
Grønborg S, Risom L, Ek J, Larsen KB, Scheie D, Petkov Y, Larsen VA, Dunø M, Joensen F, Østergaard E
European journal of human genetics : EJHG 2018 Oct;26(10):1512-1520
European journal of human genetics : EJHG 2018 Oct;26(10):1512-1520
ICR suckling mouse model of Zika virus infection for disease modeling and drug validation.
Wu YH, Tseng CK, Lin CK, Wei CK, Lee JC, Young KC
PLoS neglected tropical diseases 2018 Oct;12(10):e0006848
PLoS neglected tropical diseases 2018 Oct;12(10):e0006848
Effects of bone morphogenic protein-2 loaded on the 3D-printed MesoCS scaffolds.
Huang KH, Lin YH, Shie MY, Lin CP
Journal of the Formosan Medical Association = Taiwan yi zhi 2018 Oct;117(10):879-887
Journal of the Formosan Medical Association = Taiwan yi zhi 2018 Oct;117(10):879-887
Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer.
Zhang K, Wang J, Yang L, Yuan YC, Tong TR, Wu J, Yun X, Bonner M, Pangeni R, Liu Z, Yuchi T, Kim JY, Raz DJ
Molecular cancer 2018 Oct 22;17(1):153
Molecular cancer 2018 Oct 22;17(1):153
Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target.
Hung CS, Wang SC, Yen YT, Lee TH, Wen WC, Lin RK
International journal of molecular sciences 2018 Oct 10;19(10)
International journal of molecular sciences 2018 Oct 10;19(10)
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation.
Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD
The Journal of experimental medicine 2018 Oct 1;215(10):2686-2695
The Journal of experimental medicine 2018 Oct 1;215(10):2686-2695
Differential regulation of MyD88- and TRIF-dependent signaling pathways of Toll-like receptors by cardamonin.
Kim AY, Shim HJ, Kim SY, Heo S, Youn HS
International immunopharmacology 2018 Nov;64:1-9
International immunopharmacology 2018 Nov;64:1-9
A high-throughput pipeline for validation of antibodies.
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, Nyman TA, Stensland ME, Zhou W, de Souza GA, Holden L, Stuchly J, Templin M, Lund-Johansen F
Nature methods 2018 Nov;15(11):909-912
Nature methods 2018 Nov;15(11):909-912
Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation.
Shen CC, Hsu MN, Chang CW, Lin MW, Hwu JR, Tu Y, Hu YC
Nucleic acids research 2018 Nov 20;
Nucleic acids research 2018 Nov 20;
The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo.
Cruz-Nova P, Schnoor M, Correa-Basurto J, Bello M, Briseño-Diaz P, Rojo-Domínguez A, Ortiz-Mendoza CM, Guerrero-Aguirre J, García-Vázquez FJ, Hernández-Rivas R, Thompson-Bonilla MDR, Vargas M
BMC cancer 2018 Nov 1;18(1):1056
BMC cancer 2018 Nov 1;18(1):1056
Caveolin-1 down-regulation is required for Wnt5a-Frizzled 2 signalling in Ha-RasV12 -induced cell transformation.
Lin HK, Lin HH, Chiou YW, Wu CL, Chiu WT, Tang MJ
Journal of cellular and molecular medicine 2018 May;22(5):2631-2643
Journal of cellular and molecular medicine 2018 May;22(5):2631-2643
cDNA Microarray Analysis and Influx Transporter OATP1B1 in Liver Cells After Exposure to Gadoxetate Disodium, a Gadolinium-based Contrast Agent in MRI Liver Imaging.
Lu CC, Chen WK, Chiang JH, Tsai YF, Juan YN, Lin PC, Tyan YS, Yang JS
In vivo (Athens, Greece) 2018 May-Jun;32(3):677-684
In vivo (Athens, Greece) 2018 May-Jun;32(3):677-684
Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair.
Chen CC, Chen CY, Ueng SH, Hsueh C, Yeh CT, Ho JY, Chou LF, Wang TH
Cell death & disease 2018 May 1;9(5):543
Cell death & disease 2018 May 1;9(5):543
AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling.
Chen J, Yang YF, Yang Y, Zou P, Chen J, He Y, Shui SL, Cui YR, Bai R, Liang YJ, Hu Y, Jiang B, Lu L, Zhang X, Liu J, Xu J
Nature microbiology 2018 Mar;3(3):302-309
Nature microbiology 2018 Mar;3(3):302-309
Extrahepatic angiogenesis hinders recovery of portal hypertension and collaterals in rats with cirrhosis resolution.
Hsu SJ, Tsai MH, Chang CC, Hsieh YH, Huang HC, Lee FY, Chuang CL, Hou MC, Lee SD
Clinical science (London, England : 1979) 2018 Mar 30;132(6):669-683
Clinical science (London, England : 1979) 2018 Mar 30;132(6):669-683
EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma.
Lee HY, Chen CK, Ho CM, Lee SS, Chang CY, Chen KJ, Jou YS
Oncotarget 2018 Mar 2;9(17):13193-13205
Oncotarget 2018 Mar 2;9(17):13193-13205
Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling.
Chang HP, Lu CC, Chiang JH, Tsai FJ, Juan YN, Tsao JW, Chiu HY, Yang JS
International journal of oncology 2018 Mar 2;
International journal of oncology 2018 Mar 2;
Ghrelin ameliorates acute lung injury induced by oleic acid via inhibition of endoplasmic reticulum stress.
Tian X, Liu Z, Yu T, Yang H, Feng L
Life sciences 2018 Mar 1;196:1-8
Life sciences 2018 Mar 1;196:1-8
The double-edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation.
Jheng JR, Chen YS, Ao UI, Chan DC, Huang JW, Hung KY, Tarng DC, Chiang CK
Journal of cachexia, sarcopenia and muscle 2018 Jun;9(3):570-584
Journal of cachexia, sarcopenia and muscle 2018 Jun;9(3):570-584
Scutellaria baicalensis regulates FFA metabolism to ameliorate NAFLD through the AMPK-mediated SREBP signaling pathway.
Chen Q, Liu M, Yu H, Li J, Wang S, Zhang Y, Qiu F, Wang T
Journal of natural medicines 2018 Jun;72(3):655-666
Journal of natural medicines 2018 Jun;72(3):655-666
Posttranslational regulation of CYP2J2 by nitric oxide.
Park JW, Lee CM, Cheng JS, Morgan ET
Free radical biology & medicine 2018 Jun;121:149-156
Free radical biology & medicine 2018 Jun;121:149-156
Changes in plasma 5-HT levels and equine leukocyte SERT expression in response to treadmill exercise.
D'Ascola A, Bruschetta G, Zanghì G, Campo S, Medica P, Campana S, Ferlazzo G, Gibbs BF, Ferlazzo AM
Research in veterinary science 2018 Jun;118:184-190
Research in veterinary science 2018 Jun;118:184-190
ER stress attenuation by Aloe-derived polysaccharides in the protection of pancreatic β-cells from free fatty acid-induced lipotoxicity.
Kim K, Chung MH, Park S, Cha J, Baek JH, Lee SY, Choi SY
Biochemical and biophysical research communications 2018 Jun 7;500(3):797-803
Biochemical and biophysical research communications 2018 Jun 7;500(3):797-803
The Potential of Brown Adipogenesis and Browning in Porcine Bone Marrow-derived Mesenchymal Stem Cells.
Chen YC, Yu YH
Journal of animal science 2018 Jun 7;
Journal of animal science 2018 Jun 7;
ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts.
Cheal SM, Ruan S, Veach DR, Longo VA, Punzalan BJ, Wu J, Fung EK, Kelly MP, Kirshner JR, Giurleo JT, Ehrlich G, Han AQ, Thurston G, Olson WC, Zanzonico PB, Larson SM, Carrasquillo JA
Molecular pharmaceutics 2018 Jun 4;15(6):2133-2141
Molecular pharmaceutics 2018 Jun 4;15(6):2133-2141
Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.
Garcia-Bermudez J, Baudrier L, La K, Zhu XG, Fidelin J, Sviderskiy VO, Papagiannakopoulos T, Molina H, Snuderl M, Lewis CA, Possemato RL, Birsoy K
Nature cell biology 2018 Jul;20(7):775-781
Nature cell biology 2018 Jul;20(7):775-781
Role of the ERp57 protein (1,25D3-MARRS receptor) in murine mammary gland growth and development.
Wilkin AM, Harnett A, Underschultz M, Cragg C, Meckling KA
Steroids 2018 Jul;135:63-68
Steroids 2018 Jul;135:63-68
Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.
Phadwal K, Kurian D, Salamat MKF, MacRae VE, Diack AB, Manson JC
Scientific reports 2018 Jul 3;8(1):10004
Scientific reports 2018 Jul 3;8(1):10004
Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors.
Liew PL, Huang RL, Weng YC, Fang CL, Hui-Ming Huang T, Lai HC
International journal of cancer 2018 Jul 15;143(2):355-367
International journal of cancer 2018 Jul 15;143(2):355-367
Rehydration with fructose worsens dehydration-induced renal damage.
Milagres T, García-Arroyo FE, Lanaspa MA, Garcia G, Ishimoto T, Andres-Hernando A, Kuwabara M, Jensen T, Sato Y, Glaser J, Sánchez-Lozada LG, Johnson RJ, Roncal-Jimenez C
BMC nephrology 2018 Jul 13;19(1):180
BMC nephrology 2018 Jul 13;19(1):180
Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus.
Matsumoto K, Kawanaka H, Hori M, Kusamori K, Utsumi D, Tsukahara T, Amagase K, Horie S, Yamamoto A, Ozaki H, Mori Y, Kato S
American journal of physiology. Gastrointestinal and liver physiology 2018 Jul 1;315(1):G104-G116
American journal of physiology. Gastrointestinal and liver physiology 2018 Jul 1;315(1):G104-G116
ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.
Yang JS, Lee CY, Cho HC, Lu CC, Kuo SC, Wen YF, Tsai FJ, Lee MR, Tsai SC
Oncology reports 2018 Jan;39(1):383-391
Oncology reports 2018 Jan;39(1):383-391
Global chondrocyte gene expression after a single anabolic loading period: Time evolution and re-inducibility of mechano-responses.
Scholtes S, Krämer E, Weisser M, Roth W, Luginbühl R, Grossner T, Richter W
Journal of cellular physiology 2018 Jan;233(1):699-711
Journal of cellular physiology 2018 Jan;233(1):699-711
MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.
Fu JH, Yang S, Nan CJ, Zhou CC, Lu DQ, Li S, Mu HQ
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357
MiR-182 affects renal cancer cell proliferation, apoptosis, and invasion by regulating PI3K/AKT/mTOR signaling pathway.
Fu JH, Yang S, Nan CJ, Zhou CC, Lu DQ, Li S, Mu HQ
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357
European review for medical and pharmacological sciences 2018 Jan;22(2):351-357
Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis.
Matsumoto K, Yamaba R, Inoue K, Utsumi D, Tsukahara T, Amagase K, Tominaga M, Kato S
British journal of pharmacology 2018 Jan;175(1):84-99
British journal of pharmacology 2018 Jan;175(1):84-99
LRWD1 Regulates Microtubule Nucleation and Proper Cell Cycle Progression in the Human Testicular Embryonic Carcinoma Cells.
Wang CY, Hong YH, Syu JS, Tsai YC, Liu XY, Chen TY, Su YM, Kuo PL, Lin YM, Teng YN
Journal of cellular biochemistry 2018 Jan;119(1):314-326
Journal of cellular biochemistry 2018 Jan;119(1):314-326
Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis.
Wu YH, Lee YH, Shih HY, Chen SH, Cheng YC, Tsun-Yee Chiu D
Cell death & disease 2018 Jan 9;9(1):10
Cell death & disease 2018 Jan 9;9(1):10
Effects of the RNA-binding protein, KSRP, on innate immune response against Helicobacter pylori infection in mice.
Li N, Cao M, Yi S, Cheng J, Wang L, Tao Y, Wu D, Peng J, Zhang M, Qi P, Zhao J
Biochemical and biophysical research communications 2018 Jan 8;495(2):1573-1579
Biochemical and biophysical research communications 2018 Jan 8;495(2):1573-1579
Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5.
Chen CY, Chen CC, Shieh TM, Hsueh C, Wang SH, Leu YL, Lian JH, Wang TH
International journal of molecular sciences 2018 Jan 27;19(2)
International journal of molecular sciences 2018 Jan 27;19(2)
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity.
Chou YT, Hsu FF, Hu DY, Chen YC, Hsu YH, Hsu JT, Chau LY
Journal of biomedical science 2018 Jan 23;25(1):6
Journal of biomedical science 2018 Jan 23;25(1):6
Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress.
Hao W, Yang R, Yang Y, Jin S, Li Y, Yuan F, Guo Q, Xiao L, Wang X, Wang F, Wu Y, Teng X
Life sciences 2018 Jan 15;193:1-8
Life sciences 2018 Jan 15;193:1-8
Pleurotus sajor-caju can be used to synthesize silver nanoparticles with antifungal activity against Candida albicans.
Musa SF, Yeat TS, Kamal LZM, Tabana YM, Ahmed MA, El Ouweini A, Lim V, Keong LC, Sandai D
Journal of the science of food and agriculture 2018 Feb;98(3):1197-1207
Journal of the science of food and agriculture 2018 Feb;98(3):1197-1207
miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-PI3K/AKT/mTOR Signaling Pathway.
Wang L, Tang B, Han H, Mao D, Chen J, Zeng Y, Xiong M
Cancer biotherapy & radiopharmaceuticals 2018 Feb;33(1):32-38
Cancer biotherapy & radiopharmaceuticals 2018 Feb;33(1):32-38
PP2A deactivation is a common event in oral cancer and reactivation by FTY720 shows promising therapeutic potential.
Velmurugan BK, Lee CH, Chiang SL, Hua CH, Chen MC, Lin SH, Yeh KT, Ko YC
Journal of cellular physiology 2018 Feb;233(2):1300-1311
Journal of cellular physiology 2018 Feb;233(2):1300-1311
Proteomic Profiling of Brain and Testis Reveals the Diverse Changes in Ribosomal Proteins in fmr1 Knockout Mice.
Xu B, Zhang Y, Zhan S, Wang X, Zhang H, Meng X, Ge W
Neuroscience 2018 Feb 10;371:469-483
Neuroscience 2018 Feb 10;371:469-483
ΔNp63 promotes abnormal epidermal proliferation in arsenical skin cancers.
Lu JH, Liao WT, Lee CH, Chang KL, Ke HL, Yu HS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:57-66
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:57-66
Early intervention of N-acetylcysteine better improves insulin resistance in diet-induced obesity mice.
Shen FC, Weng SW, Tsao CF, Lin HY, Chang CS, Lin CY, Lian WS, Chuang JH, Lin TK, Liou CW, Wang PW
Free radical research 2018 Dec;52(11-12):1296-1310
Free radical research 2018 Dec;52(11-12):1296-1310
Chemical composition and biological activity of extracts from fruiting bodies and mycelial cultures of Fomitopsis betulina.
Sułkowska-Ziaja K, Szewczyk A, Galanty A, Gdula-Argasińska J, Muszyńska B
Molecular biology reports 2018 Dec;45(6):2535-2544
Molecular biology reports 2018 Dec;45(6):2535-2544
Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts.
Chen JT, Wang CY, Chen MH
Journal of the Formosan Medical Association = Taiwan yi zhi 2018 Dec;117(12):1115-1123
Journal of the Formosan Medical Association = Taiwan yi zhi 2018 Dec;117(12):1115-1123
Inhibition of autophagy by chloroquine makes chemotherapy in nasopharyngeal carcinoma more efficient.
Aga T, Endo K, Tsuji A, Aga M, Moriyama-Kita M, Ueno T, Nakanishi Y, Hatano M, Kondo S, Sugimoto H, Wakisaka N, Yoshizaki T
Auris, nasus, larynx 2018 Dec 1;
Auris, nasus, larynx 2018 Dec 1;
miR-4725-3p targeting stromal interacting molecule 1 signaling is involved in xanthohumol inhibition of glioma cell invasion.
Ho KH, Chang CK, Chen PH, Wang YJ, Chang WC, Chen KC
Journal of neurochemistry 2018 Aug;146(3):269-288
Journal of neurochemistry 2018 Aug;146(3):269-288
Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.
Myeong J, Ko J, Kwak M, Kim J, Woo J, Ha K, Hong C, Yang D, Kim HJ, Jeon JH, So I
Scientific reports 2018 Aug 14;8(1):12117
Scientific reports 2018 Aug 14;8(1):12117
Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia.
Terasaki M, Ogawa Y, Endo T, Maeda H, Hamada J, Osada K, Miyashita K, Mutoh M
Anticancer research 2018 Apr;38(4):2169-2179
Anticancer research 2018 Apr;38(4):2169-2179
Inhibitory effects of selenium on cadmium-induced cytotoxicity in PC12 cells via regulating oxidative stress and apoptosis.
Binte Hossain KF, Rahman MM, Sikder MT, Saito T, Hosokawa T, Kurasaki M
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Apr;114:180-189
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 Apr;114:180-189
Development of a computational promoter with highly efficient expression in tumors.
Ho SY, Chang BH, Chung CH, Lin YL, Chuang CH, Hsieh PJ, Huang WC, Tsai NM, Huang SC, Liu YK, Lo YC, Liao KW
BMC cancer 2018 Apr 27;18(1):480
BMC cancer 2018 Apr 27;18(1):480
Anti-inflammatory activities of garlic sprouts, a source of α-linolenic acid and 5-hydroxy-l-tryptophan, in RAW 264.7 cells.
Gdula-Argasińska J, Paśko P, Sułkowska-Ziaja K, Kała K, Muszyńska B
Acta biochimica Polonica 2017;64(3):551-559
Acta biochimica Polonica 2017;64(3):551-559
Uncovering the Molecular Mechanism of Anti-Allergic Activity of Silkworm Pupa-Grown Cordyceps militaris Fruit Body.
Wu TF, Chan YY, Shi WY, Jhong MT
The American journal of Chinese medicine 2017;45(3):497-513
The American journal of Chinese medicine 2017;45(3):497-513
9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1, 2-c]quinolin-11-one (BPIQ), A Quinoline Derivative Inhibits Human Hepatocellular Carcinoma Cells by Inducing ER Stress and Apoptosis.
Chang WT, Fong Y, Chuang SC, Chou CK, Chou HL, Yang CF, Tseng CH, Chen YL, Chiu CC
Anti-cancer agents in medicinal chemistry 2017;17(5):692-700
Anti-cancer agents in medicinal chemistry 2017;17(5):692-700
Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.
Uchiyama T, Okajima F, Mogi C, Tobo A, Tomono S, Sato K
PloS one 2017;12(6):e0178769
PloS one 2017;12(6):e0178769
The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA.
Lee CC, Chen PH, Ho KH, Shih CM, Cheng CH, Lin CW, Cheng KT, Liu AJ, Chen KC
PloS one 2017;12(3):e0173890
PloS one 2017;12(3):e0173890
Detection and quantification of dengue virus using a novel biosensor system based on dengue NS3 protease activity.
Hsieh MS, Chen MY, Hsieh CH, Pan CH, Yu GY, Chen HW
PloS one 2017;12(11):e0188170
PloS one 2017;12(11):e0188170
The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice.
Dai YC, Wang SC, Haque MM, Lin WH, Lin LC, Chen CH, Liu YW
PloS one 2017;12(10):e0186214
PloS one 2017;12(10):e0186214
The Impact of MicroRNA-223-3p on IL-17 Receptor D Expression in Synovial Cells.
Moriya N, Shibasaki S, Karasaki M, Iwasaki T
PloS one 2017;12(1):e0169702
PloS one 2017;12(1):e0169702
Torenia concolor Lindley var. formosana Yamazaki extracts improve inflammatory response and lipid accumulation via PPARs activation.
Liang YC, Hu JC, Li PY, Huang GJ, Kuo YH, Chao CY
BioMedicine 2017 Sep;7(3):18
BioMedicine 2017 Sep;7(3):18
3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.
Chao W, Deng JS, Huang SS, Li PY, Liang YC, Huang GJ
International immunopharmacology 2017 Sep;50:77-86
International immunopharmacology 2017 Sep;50:77-86
G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells.
Tsukahara T, Hamouda N, Utsumi D, Matsumoto K, Amagase K, Kato S
Pharmacological research 2017 Sep;123:27-39
Pharmacological research 2017 Sep;123:27-39
Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement.
Chen YC, Shie MY, Wu YA, Lee KA, Wei LJ, Shen YF
Journal of the Formosan Medical Association = Taiwan yi zhi 2017 Sep;116(9):679-688
Journal of the Formosan Medical Association = Taiwan yi zhi 2017 Sep;116(9):679-688
The Beneficial Effects of Allicin in Chronic Kidney Disease Are Comparable to Losartan.
García Trejo EMÁ, Arellano Buendía AS, Sánchez Reyes O, García Arroyo FE, Arguello García R, Loredo Mendoza ML, Tapia E, Sánchez Lozada LG, Osorio Alonso H
International journal of molecular sciences 2017 Sep 16;18(9)
International journal of molecular sciences 2017 Sep 16;18(9)
Induction of Anoikis in Human Colorectal Cancer Cells by Fucoxanthinol.
Terasaki M, Maeda H, Miyashita K, Mutoh M
Nutrition and cancer 2017 Oct;69(7):1043-1052
Nutrition and cancer 2017 Oct;69(7):1043-1052
Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells.
Lan HC, Wu KY, Lin IW, Yang ZJ, Chang AA, Hu MC
Chemosphere 2017 Oct;185:237-246
Chemosphere 2017 Oct;185:237-246
The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer.
Hou MF, Luo CW, Chang TM, Hung WC, Chen TY, Tsai YL, Chai CY, Pan MR
Experimental cell research 2017 Oct 15;359(2):458-465
Experimental cell research 2017 Oct 15;359(2):458-465
A novel function of neuroglobin for neuroregeneration in mice after optic nerve injury.
Sugitani K, Koriyama Y, Sera M, Arai K, Ogai K, Wakasugi K
Biochemical and biophysical research communications 2017 Nov 25;493(3):1254-1259
Biochemical and biophysical research communications 2017 Nov 25;493(3):1254-1259
Long noncoding RNA MIAT promotes non-small cell lung cancer proliferation and metastasis through MMP9 activation.
Lai IL, Yang CA, Lin PC, Chan WL, Lee YT, Yen JC, Chang YS, Chang JG
Oncotarget 2017 Nov 17;8(58):98148-98162
Oncotarget 2017 Nov 17;8(58):98148-98162
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Yeh CJ, Chen CC, Leu YL, Lin MW, Chiu MM, Wang SH
Scientific reports 2017 Nov 15;7(1):15599
Scientific reports 2017 Nov 15;7(1):15599
Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers.
Chiu JH, Wen CS, Wang JY, Hsu CY, Tsai YF, Hung SC, Tseng LM, Shyr YM
Journal of translational medicine 2017 May 4;15(1):97
Journal of translational medicine 2017 May 4;15(1):97
Cytotoxic effects of cadmium and zinc co-exposure in PC12 cells and the underlying mechanism.
Rahman MM, Ukiana J, Uson-Lopez R, Sikder MT, Saito T, Kurasaki M
Chemico-biological interactions 2017 May 1;269:41-49
Chemico-biological interactions 2017 May 1;269:41-49
Metabolic adaptation via regulated enzyme degradation in the pathogenic yeast Candida albicans.
Ting SY, Ishola OA, Ahmed MA, Tabana YM, Dahham S, Agha MT, Musa SF, Muhammed R, Than LT, Sandai D
Journal de mycologie medicale 2017 Mar;27(1):98-108
Journal de mycologie medicale 2017 Mar;27(1):98-108
Molecular mechanisms of the effects of the ethanolic extract of Muntingia calabura Linn. fruit on lipopolysaccharide-induced pro-inflammatory mediators in macrophages.
Lin JT, Chang YY, Chen YC, Shen BY, Yang DJ
Food & function 2017 Mar 22;8(3):1245-1253
Food & function 2017 Mar 22;8(3):1245-1253
Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth.
Syu JS, Baba T, Huang JY, Ogawa H, Hsieh CH, Hu JX, Chen TY, Lin TC, Tsuchiya M, Morohashi KI, Huang BM, Lu FL, Wang CY
Scientific reports 2017 Mar 21;7(1):240
Scientific reports 2017 Mar 21;7(1):240
Inhibitory effects of rosmarinic acid on pterygium epithelial cells through redox imbalance and induction of extrinsic and intrinsic apoptosis.
Chen YY, Tsai CF, Tsai MC, Hsu YW, Lu FJ
Experimental eye research 2017 Jul;160:96-105
Experimental eye research 2017 Jul;160:96-105
Yeast Cip1 is activated by environmental stress to inhibit Cdk1-G1 cyclins via Mcm1 and Msn2/4.
Chang YL, Tseng SF, Huang YC, Shen ZJ, Hsu PH, Hsieh MH, Yang CW, Tognetti S, Canal B, Subirana L, Wang CW, Chen HT, Lin CY, Posas F, Teng SC
Nature communications 2017 Jul 4;8(1):56
Nature communications 2017 Jul 4;8(1):56
Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells.
Beltejar MG, Lau HT, Golkowski MG, Ong SE, Beavo JA
Proceedings of the National Academy of Sciences of the United States of America 2017 Jul 25;114(30):E6240-E6249
Proceedings of the National Academy of Sciences of the United States of America 2017 Jul 25;114(30):E6240-E6249
Epigenetic regulation of the glucose transporter gene Slc2a1 by β-hydroxybutyrate underlies preferential glucose supply to the brain of fasted mice.
Tanegashima K, Sato-Miyata Y, Funakoshi M, Nishito Y, Aigaki T, Hara T
Genes to cells : devoted to molecular & cellular mechanisms 2017 Jan;22(1):71-83
Genes to cells : devoted to molecular & cellular mechanisms 2017 Jan;22(1):71-83
Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila.
Lee S, Bao H, Ishikawa Z, Wang W, Lim HY
PLoS genetics 2017 Jan;13(1):e1006555
PLoS genetics 2017 Jan;13(1):e1006555
Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells.
Xiao LY, Kan WM
European journal of pharmacology 2017 Jan 5;794:201-208
European journal of pharmacology 2017 Jan 5;794:201-208
Therapeutic vaccine targeting Epstein-Barr virus latent protein, LMP1, suppresses LMP1-expressing tumor growth and metastasis in vivo.
Lin MC, Lin YC, Chen ST, Young TH, Lou PJ
BMC cancer 2017 Jan 5;17(1):18
BMC cancer 2017 Jan 5;17(1):18
Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.
Eguchi A, Lazaro RG, Wang J, Kim J, Povero D, Willliams B, Ho SB, Stärkel P, Schnabl B, Ohno-Machado L, Tsukamoto H, Feldstein AE
Hepatology (Baltimore, Md.) 2017 Feb;65(2):475-490
Hepatology (Baltimore, Md.) 2017 Feb;65(2):475-490
Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro.
Baek JM, Ahn SJ, Cheon YH, Lee MS, Oh J, Kim JY
Molecular medicine reports 2017 Feb;15(2):784-792
Molecular medicine reports 2017 Feb;15(2):784-792
Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer.
Roy D, Mondal S, Khurana A, Jung DB, Hoffmann R, He X, Kalogera E, Dierks T, Hammond E, Dredge K, Shridhar V
Scientific reports 2017 Feb 7;7:41977
Scientific reports 2017 Feb 7;7:41977
Effects of exosome-like vesicles on cumulus expansion in pigs in vitro.
Matsuno Y, Onuma A, Fujioka YA, Yasuhara K, Fujii W, Naito K, Sugiura K
The Journal of reproduction and development 2017 Feb 16;63(1):51-58
The Journal of reproduction and development 2017 Feb 16;63(1):51-58
Apolipoprotein M Inhibits Angiogenic and Inflammatory Response by Sphingosine 1-Phosphate on Retinal Pigment Epithelium Cells.
Terao R, Honjo M, Aihara M
International journal of molecular sciences 2017 Dec 31;19(1)
International journal of molecular sciences 2017 Dec 31;19(1)
Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma.
Chiu YS, Hsing CH, Li CF, Lee CY, Hsu YH, Chang MS
Scientific reports 2017 Dec 14;7(1):17609
Scientific reports 2017 Dec 14;7(1):17609
KH-type splicing regulatory protein mediate inflammatory response in gastric epithelial cells induced by lipopolysaccharide.
Chen C, Cao M, Wu D, Li N, Peng J, Song L, Qi P, Zhang M, Zhao J
Cell biology international 2017 Aug;41(8):871-878
Cell biology international 2017 Aug;41(8):871-878
Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells.
Yamashita N, Yashiro M, Ogawa H, Namba H, Nosaka N, Fujii Y, Morishima T, Tsukahara H, Yamada M
Biochemical and biophysical research communications 2017 Aug 5;489(4):466-471
Biochemical and biophysical research communications 2017 Aug 5;489(4):466-471
Electroacupuncture Promotes Recovery of Motor Function and Reduces Dopaminergic Neuron Degeneration in Rodent Models of Parkinson's Disease.
Lin JG, Chen CJ, Yang HB, Chen YH, Hung SY
International journal of molecular sciences 2017 Aug 24;18(9)
International journal of molecular sciences 2017 Aug 24;18(9)
SHP-2 phosphatase controls aryl hydrocarbon receptor-mediated ER stress response in mast cells.
Wang HC, Zhou Y, Huang SK
Archives of toxicology 2017 Apr;91(4):1739-1748
Archives of toxicology 2017 Apr;91(4):1739-1748
The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity.
Chen PH, Shen WL, Shih CM, Ho KH, Cheng CH, Lin CW, Lee CC, Liu AJ, Chen KC
Neuropharmacology 2017 Apr;116:300-314
Neuropharmacology 2017 Apr;116:300-314
Separation of photoreceptor cell compartments in mouse retina for protein analysis.
Rose K, Walston ST, Chen J
Molecular neurodegeneration 2017 Apr 11;12(1):28
Molecular neurodegeneration 2017 Apr 11;12(1):28
Induction of cyclooxygenase-2 gene by Candida albicans through EGFR, ERK, and p38 pathways in human urinary epithelium.
Wang SH, Wang SC, Chen PC, Wang ST, Liu YW
Medical mycology 2017 Apr 1;55(3):314-322
Medical mycology 2017 Apr 1;55(3):314-322
Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis.
Wang HS, Nie X, Wu RB, Yuan HW, Ma YH, Liu XL, Zhang JY, Deng XL, Na Q, Jin HY, Bian YC, Gao YM, Wang YD, Chen WD
OncoTargets and therapy 2016;9:3849-60
OncoTargets and therapy 2016;9:3849-60
EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells.
Hsieh YY, Lo HL, Yang PM
American journal of cancer research 2016;6(8):1661-80
American journal of cancer research 2016;6(8):1661-80
Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma.
Wang SC, Huang CC, Shen CH, Lin LC, Zhao PW, Chen SY, Deng YC, Liu YW
PloS one 2016;11(7):e0159102
PloS one 2016;11(7):e0159102
The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages.
Chen CC, Lin MW, Liang CJ, Wang SH
PloS one 2016;11(7):e0158662
PloS one 2016;11(7):e0158662
Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure.
Nagai-Okatani C, Minamino N
PloS one 2016;11(6):e0150210
PloS one 2016;11(6):e0150210
Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer.
Chen WC, Wang CY, Hung YH, Weng TY, Yen MC, Lai MD
PloS one 2016;11(5):e0155660
PloS one 2016;11(5):e0155660
Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning.
Tung H, Wei SC, Lo HR, Chao YC
PloS one 2016;11(2):e0148578
PloS one 2016;11(2):e0148578
The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
Chen PH, Cheng CH, Shih CM, Ho KH, Lin CW, Lee CC, Liu AJ, Chang CK, Chen KC
PloS one 2016;11(11):e0167096
PloS one 2016;11(11):e0167096
The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
Chiu WC, Lee YC, Su YH, Wang YY, Tsai CH, Hou YA, Wang CH, Huang YF, Huang CJ, Chou SH, Hsieh PW, Yuan SF
PloS one 2016;11(11):e0166453
PloS one 2016;11(11):e0166453
The contribution of toll-like receptor 2 on Helicobacter pylori activation of the nuclear factor-kappa B signaling pathway in gastric epithelial cells.
Li S, Cao M, Song L, Qi P, Chen C, Wang X, Li N, Peng J, Wu D, Hu G, Zhao J
Microbial pathogenesis 2016 Sep;98:63-8
Microbial pathogenesis 2016 Sep;98:63-8
CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL).
Oldenburg D, Ru Y, Weinhaus B, Cash S, Theodorescu D, Guin S
BMC cancer 2016 Sep 5;16:713
BMC cancer 2016 Sep 5;16:713
Resolvin D1 down-regulates CYP1A1 and PTGS2 gene in the HUVEC cells treated with benzo(a)pyrene.
Gdula-Argasińska J, Czepiel J, Totoń-Żurańska J, Jurczyszyn A, Wołkow P, Librowski T, Perucki W
Pharmacological reports : PR 2016 Oct;68(5):939-44
Pharmacological reports : PR 2016 Oct;68(5):939-44
Biomimicking Platelet-Monocyte Interactions as a Novel Targeting Strategy for Heart Healing.
Cheng B, Toh EK, Chen KH, Chang YC, Hu CJ, Wu HC, Chau LY, Chen P, Hsieh PC
Advanced healthcare materials 2016 Oct;5(20):2686-2697
Advanced healthcare materials 2016 Oct;5(20):2686-2697
MicroRNA-214 exerts a Cardio-protective effect by inhibition of fibrosis.
Dong H, Dong S, Zhang L, Gao X, Lv G, Chen W, Shao S
Anatomical record (Hoboken, N.J. : 2007) 2016 Oct;299(10):1348-57
Anatomical record (Hoboken, N.J. : 2007) 2016 Oct;299(10):1348-57
The effects of cytotoxic necrotizing factor 1 expression in the uptake of Escherichia coli K1 by macrophages and the onset of meningitis in newborn mice.
Chang AC, Krishnan S, Prasadarao NV
Virulence 2016 Oct 2;7(7):806-18
Virulence 2016 Oct 2;7(7):806-18
In vitro cultures of Bacopa monnieri and an analysis of selected groups of biologically active metabolites in their biomass.
Muszyńska B, Łojewski M, Sułkowska-Ziaja K, Szewczyk A, Gdula-Argasińska J, Hałaszuk P
Pharmaceutical biology 2016 Nov;54(11):2443-2453
Pharmaceutical biology 2016 Nov;54(11):2443-2453
Redistribution of Cav2.1 channels and calcium ions in nerve terminals following end-to-side neurorrhaphy: ionic imaging analysis by TOF-SIMS.
Liu CH, Chang HM, Tseng TJ, Lan CT, Chen LY, Youn SC, Lee JJ, Mai FD, Chou JF, Liao WC
Histochemistry and cell biology 2016 Nov;146(5):599-608
Histochemistry and cell biology 2016 Nov;146(5):599-608
Corrosion-Activated Chemotherapeutic Function of Nanoparticulate Platinum as a Cisplatin Resistance-Overcoming Prodrug with Limited Autophagy Induction.
Cheng HJ, Wu TH, Chien CT, Tu HW, Cha TS, Lin SY
Small (Weinheim an der Bergstrasse, Germany) 2016 Nov;12(44):6124-6133
Small (Weinheim an der Bergstrasse, Germany) 2016 Nov;12(44):6124-6133
The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death.
Chen PH, Chang CK, Shih CM, Cheng CH, Lin CW, Lee CC, Liu AJ, Ho KH, Chen KC
Neuropharmacology 2016 Nov;110(Pt A):362-375
Neuropharmacology 2016 Nov;110(Pt A):362-375
WITHDRAWN: Decreased level of endogenous ghrelin is involved in the progression of lung injury induced by oleic acid.
Liu Z, Yu T, Yang H, Tian X, Feng L
Life sciences 2016 Nov 25;
Life sciences 2016 Nov 25;
The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice.
Dizhoor AM, Olshevskaya EV, Peshenko IV
The Journal of biological chemistry 2016 Nov 18;291(47):24504-24516
The Journal of biological chemistry 2016 Nov 18;291(47):24504-24516
A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA.
Wang YT, Chiang HH, Huang YS, Hsu CL, Yang PJ, Juan HF, Yang WS
Cell death & disease 2016 Nov 10;7(11):e2458
Cell death & disease 2016 Nov 10;7(11):e2458
Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways.
Lii CK, Chang JW, Chen JJ, Chen HW, Liu KL, Yeh SL, Wang TS, Liu SH, Tsai CH, Li CC
Oncotarget 2016 May 3;7(18):25162-79
Oncotarget 2016 May 3;7(18):25162-79
MicroRNA let-7b induces lens epithelial cell apoptosis by targeting leucine-rich repeat containing G protein-coupled receptor 4 (Lgr4) in age-related cataract.
Dong Y, Zheng Y, Xiao J, Zhu C, Zhao M
Experimental eye research 2016 Jun;147:98-104
Experimental eye research 2016 Jun;147:98-104
Duodenojejunal Bypass Leads to Altered Gut Microbiota and Strengthened Epithelial Barriers in Rats.
Yang PJ, Yang WS, Nien HC, Chen CN, Lee PH, Yu LC, Lin MT
Obesity surgery 2016 Jul;26(7):1576-83
Obesity surgery 2016 Jul;26(7):1576-83
Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells.
Chen MF, Huang SJ, Huang CC, Liu PS, Lin KI, Liu CW, Hsieh WC, Shiu LY, Chen CH
BMC cancer 2016 Jul 26;16:532
BMC cancer 2016 Jul 26;16:532
Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.
Zhang Y, Wu Y, Mao P, Li F, Han X, Zhang Y, Jiang S, Chen Y, Huang J, Liu D, Zhao Y, Ma W, Songyang Z
Nucleic acids research 2016 Jan 29;44(2):761-75
Nucleic acids research 2016 Jan 29;44(2):761-75
Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells.
Chen NC, Chyau CC, Lee YJ, Tseng HC, Chou FP
Scientific reports 2016 Feb 3;6:20417
Scientific reports 2016 Feb 3;6:20417
Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo.
Chen L, Liu H, Wang Y, Xia H, Gong J, Li B, Yao S, Shang Y
Inflammation 2016 Dec;39(6):1981-1989
Inflammation 2016 Dec;39(6):1981-1989
Tanshinone IIA ameliorates apoptosis of cardiomyocytes induced by endoplasmic reticulum stress.
Feng J, Li S, Chen H
Experimental biology and medicine (Maywood, N.J.) 2016 Dec;241(18):2042-2048
Experimental biology and medicine (Maywood, N.J.) 2016 Dec;241(18):2042-2048
Inhibition of cytoskeletal protein carbonylation may protect against oxidative damage in traumatic brain injury.
Zhang Q, Zhang M, Huang X, Liu X, Li W
Experimental and therapeutic medicine 2016 Dec;12(6):4107-4112
Experimental and therapeutic medicine 2016 Dec;12(6):4107-4112
The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-κB signaling pathway.
Hsieh SC, Hsieh WJ, Chiang AN, Su NW, Yeh YT, Liao YC
Food & function 2016 Dec 7;7(12):4797-4803
Food & function 2016 Dec 7;7(12):4797-4803
Hepatocarcinogenesis in transgenic mice carrying hepatitis B virus pre-S/S gene with the sW172* mutation.
Lai MW, Liang KH, Lin WR, Huang YH, Huang SF, Chen TC, Yeh CT
Oncogenesis 2016 Dec 5;5(12):e273
Oncogenesis 2016 Dec 5;5(12):e273
miRNA-342 Regulates CEACAM1-induced Lumen Formation in a Three-dimensional Model of Mammary Gland Morphogenesis.
Weng C, Nguyen T, Shively JE
The Journal of biological chemistry 2016 Aug 5;291(32):16777-86
The Journal of biological chemistry 2016 Aug 5;291(32):16777-86
Induction of Lumen Formation in a Three-dimensional Model of Mammary Morphogenesis by Transcriptional Regulator ID4: ROLE OF CaMK2D IN THE EPIGENETIC REGULATION OF ID4 GENE EXPRESSION.
Nguyen T, Shively JE
The Journal of biological chemistry 2016 Aug 5;291(32):16766-76
The Journal of biological chemistry 2016 Aug 5;291(32):16766-76
DEF6 expression in ovarian carcinoma correlates with poor patient survival.
Liew PL, Fang CY, Lee YC, Lee YC, Chen CL, Chu JS
Diagnostic pathology 2016 Aug 3;11(1):68
Diagnostic pathology 2016 Aug 3;11(1):68
Mouse oocytes suppress miR-322-5p expression in ovarian granulosa cells.
Sumitomo J, Emori C, Matsuno Y, Ueno M, Kawasaki K, Endo TA, Shiroguchi K, Fujii W, Naito K, Sugiura K
The Journal of reproduction and development 2016 Aug 25;62(4):393-9
The Journal of reproduction and development 2016 Aug 25;62(4):393-9
Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor.
Wei TT, Lin YT, Tseng RY, Shun CT, Lin YC, Wu MS, Fang JM, Chen CC
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Aug 15;22(16):4158-69
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Aug 15;22(16):4158-69
Anti-IL-20 monoclonal antibody promotes bone fracture healing through regulating IL-20-mediated osteoblastogenesis.
Hsu YH, Chiu YS, Chen WY, Huang KY, Jou IM, Wu PT, Wu CH, Chang MS
Scientific reports 2016 Apr 14;6:24339
Scientific reports 2016 Apr 14;6:24339
Possible production of arsenic hemoglobin adducts via exposure to arsine.
Yamauchi T, Yamano Y, Yamanaka K, Hata A, Nakadate T, Kuroda Y, Endo Y, Endo G
Journal of occupational health 2015;57(2):161-8
Journal of occupational health 2015;57(2):161-8
Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo.
Perrigue PM, Najbauer J, Jozwiak AA, Barciszewski J, Aboody KS, Barish ME
Pathobiology of aging & age related diseases 2015;5:30052
Pathobiology of aging & age related diseases 2015;5:30052
Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo.
Perrigue PM, Najbauer J, Jozwiak AA, Barciszewski J, Aboody KS, Barish ME
Pathobiology of aging & age related diseases 2015;5:30052
Pathobiology of aging & age related diseases 2015;5:30052
Preclinical evaluation on the tumor suppression efficiency and combination drug effects of fermented wheat germ extract in human ovarian carcinoma cells.
Wang CW, Wang CK, Chang YJ, Choong CY, Lin CS, Tai CJ, Tai CJ
Evidence-based complementary and alternative medicine : eCAM 2015;2015:570785
Evidence-based complementary and alternative medicine : eCAM 2015;2015:570785
Effects of oral phosphatidic acid feeding with or without whey protein on muscle protein synthesis and anabolic signaling in rodent skeletal muscle.
Mobley CB, Hornberger TA, Fox CD, Healy JC, Ferguson BS, Lowery RP, McNally RM, Lockwood CM, Stout JR, Kavazis AN, Wilson JM, Roberts MD
Journal of the International Society of Sports Nutrition 2015;12:32
Journal of the International Society of Sports Nutrition 2015;12:32
Effects of protein type and composition on postprandial markers of skeletal muscle anabolism, adipose tissue lipolysis, and hypothalamic gene expression.
Mobley CB, Fox CD, Ferguson BS, Pascoe CA, Healy JC, McAdam JS, Lockwood CM, Roberts MD
Journal of the International Society of Sports Nutrition 2015;12:14
Journal of the International Society of Sports Nutrition 2015;12:14
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Haraguchi M, Sato M, Ozawa M
PloS one 2015;10(7):e0132260
PloS one 2015;10(7):e0132260
Cleavage of Dicer protein by I7 protease during vaccinia virus infection.
Chen JS, Li HC, Lin SI, Yang CH, Chien WY, Syu CL, Lo SY
PloS one 2015;10(3):e0120390
PloS one 2015;10(3):e0120390
Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells.
Jin C, Qin T, Barton MC, Jelinek J, Issa JP
Epigenetics 2015;10(11):1006-13
Epigenetics 2015;10(11):1006-13
Cetuximab-conjugated iron oxide nanoparticles for cancer imaging and therapy.
Tseng SH, Chou MY, Chu IM
International journal of nanomedicine 2015;10:3663-85
International journal of nanomedicine 2015;10:3663-85
Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival.
Orogo AM, Gonzalez ER, Kubli DA, Baptista IL, Ong SB, Prolla TA, Sussman MA, Murphy AN, Gustafsson ÅB
The Journal of biological chemistry 2015 Sep 4;290(36):22061-75
The Journal of biological chemistry 2015 Sep 4;290(36):22061-75
Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.
Wang TH, Lin YS, Chen Y, Yeh CT, Huang YL, Hsieh TH, Shieh TM, Hsueh C, Chen TC
Oncotarget 2015 Sep 15;6(27):23342-57
Oncotarget 2015 Sep 15;6(27):23342-57
CTRP3 acts as a negative regulator of osteoclastogenesis through AMPK-c-Fos-NFATc1 signaling in vitro and RANKL-induced calvarial bone destruction in vivo.
Kim JY, Min JY, Baek JM, Ahn SJ, Jun HY, Yoon KH, Choi MK, Lee MS, Oh J
Bone 2015 Oct;79:242-51
Bone 2015 Oct;79:242-51
Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells.
Ruan Y, Hu K, Chen H
Molecular medicine reports 2015 Oct;12(4):5796-806
Molecular medicine reports 2015 Oct;12(4):5796-806
MicroRNA-302b Enhances the Sensitivity of Hepatocellular Carcinoma Cell Lines to 5-FU via Targeting Mcl-1 and DPYD.
Cai D, He K, Chang S, Tong D, Huang C
International journal of molecular sciences 2015 Oct 6;16(10):23668-82
International journal of molecular sciences 2015 Oct 6;16(10):23668-82
Low-dose Bisphenol A Activates Cyp11a1 Gene Expression and Corticosterone Secretion in Adrenal Gland via the JNK Signaling Pathway.
Lan HC, Lin IW, Yang ZJ, Lin JH
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):26-34
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):26-34
B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.
Fei F, Joo EJ, Tarighat SS, Schiffer I, Paz H, Fabbri M, Abdel-Azim H, Groffen J, Heisterkamp N
Oncotarget 2015 May 10;6(13):11378-94
Oncotarget 2015 May 10;6(13):11378-94
Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.
Cheng HM, Chern Y, Chen IH, Liu CR, Li SH, Chun SJ, Rigo F, Bennett CF, Deng N, Feng Y, Lin CS, Yan YT, Cohen SN, Cheng TH
PLoS genetics 2015 Mar;11(3):e1005043
PLoS genetics 2015 Mar;11(3):e1005043
Three Pathways Assess Anti-Inflammatory Response of Epicatechin with Lipopolysaccharide-Mediated Macrophage RAW264.7 Cells
Yang D, Liu S, Chen Y, Hsu S, Chang Y, Lin J
Journal of Food Biochemistry 2015 June;39(3):334-343
Journal of Food Biochemistry 2015 June;39(3):334-343
N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting.
Lin PH, Lin HY, Kuo CC, Yang LT
Journal of biomedical science 2015 Jun 24;22:44
Journal of biomedical science 2015 Jun 24;22:44
Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.
Chang CH, Chan PC, Li JR, Chen CJ, Shieh JJ, Fu YC, Chen HC, Wu MJ
Oncotarget 2015 Jan 30;6(3):1478-89
Oncotarget 2015 Jan 30;6(3):1478-89
Identification of the full-length β-actin sequence and expression profiles in the tree shrew (Tupaia belangeri).
Zheng Y, Yun C, Wang Q, Smith WW, Leng J
International journal of molecular medicine 2015 Feb;35(2):519-24
International journal of molecular medicine 2015 Feb;35(2):519-24
S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells.
Liu TP, Lo HL, Wei LS, Hsiao HH, Yang PM
Anti-cancer drugs 2015 Feb;26(2):139-47
Anti-cancer drugs 2015 Feb;26(2):139-47
Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells.
Chen TY, Syu JS, Lin TC, Cheng HL, Lu FL, Wang CY
Oncogenesis 2015 Dec 21;4:e180
Oncogenesis 2015 Dec 21;4:e180
PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells.
Ho TC, Chiang YP, Chuang CK, Chen SL, Hsieh JW, Lan YW, Tsao YP
American journal of physiology. Cell physiology 2015 Aug 1;309(3):C159-68
American journal of physiology. Cell physiology 2015 Aug 1;309(3):C159-68
Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines.
Shan YS, Hsu HP, Lai MD, Yen MC, Chen WC, Fang JH, Weng TY, Chen YL
Scientific reports 2015 Apr 30;5:9783
Scientific reports 2015 Apr 30;5:9783
Impact of maternal n-3 polyunsaturated fatty acid deficiency on dendritic arbor morphology and connectivity of developing Xenopus laevis central neurons in vivo.
Igarashi M, Santos RA, Cohen-Cory S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 15;35(15):6079-92
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 15;35(15):6079-92
Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes.
Caspani EM, Crossley PH, Redondo-Garcia C, Martinez S
PloS one 2014;9(7):e101402
PloS one 2014;9(7):e101402
The untranslated regions of classic swine fever virus RNA trigger apoptosis.
Hsu WL, Chen CL, Huang SW, Wu CC, Chen IH, Nadar M, Su YP, Tsai CH
PloS one 2014;9(2):e88863
PloS one 2014;9(2):e88863
Growth inhibition of head and neck squamous cell carcinoma cells by sgRNA targeting the cyclin D1 mRNA based on TRUE gene silencing.
Iizuka S, Oridate N, Nashimoto M, Fukuda S, Tamura M
PloS one 2014;9(12):e114121
PloS one 2014;9(12):e114121
One-step generation of phenotype-expressing triple-knockout mice with heritable mutated alleles by the CRISPR/Cas9 system.
Fujii W, Onuma A, Sugiura K, Naito K
The Journal of reproduction and development 2014;60(4):324-7
The Journal of reproduction and development 2014;60(4):324-7
Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest.
Abe TK, Taniguchi M
FEBS open bio 2014;4:162-7
FEBS open bio 2014;4:162-7
Pre-conditioning with CDP-choline attenuates oxidative stress-induced cardiac myocyte death in a hypoxia/reperfusion model.
González-Pacheco H, Méndez-Domínguez A, Hernández S, López-Marure R, Vazquez-Mellado MJ, Aguilar C, Rocha-Zavaleta L
TheScientificWorldJournal 2014;2014:187071
TheScientificWorldJournal 2014;2014:187071
A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.
Lee KH, Lo HL, Tang WC, Hsiao HH, Yang PM
Scientific reports 2014 Sep 17;4:6394
Scientific reports 2014 Sep 17;4:6394
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Chuang JJ, Dai YC, Lin YL, Chen YY, Lin WH, Chan HL, Liu YW
Toxicology and applied pharmacology 2014 Sep 15;279(3):322-30
Toxicology and applied pharmacology 2014 Sep 15;279(3):322-30
Facile identification of dual FLT3-Aurora A inhibitors: a computer-guided drug design approach.
Chang Hsu Y, Ke YY, Shiao HY, Lee CC, Lin WH, Chen CH, Yen KJ, Hsu JT, Chang C, Hsieh HP
ChemMedChem 2014 May;9(5):953-61
ChemMedChem 2014 May;9(5):953-61
TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Jin C, Lu Y, Jelinek J, Liang S, Estecio MR, Barton MC, Issa JP
Nucleic acids research 2014 Jun;42(11):6956-71
Nucleic acids research 2014 Jun;42(11):6956-71
Nuclear proteomics with XRCC3 knockdown to reveal the development of doxorubicin-resistant uterine cancer.
Chang JF, Lin ST, Hung E, Lu YL, Soon May EW, Lo YW, Chou HC, Chan HL
Toxicological sciences : an official journal of the Society of Toxicology 2014 Jun;139(2):396-406
Toxicological sciences : an official journal of the Society of Toxicology 2014 Jun;139(2):396-406
TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage.
Jain AK, Allton K, Duncan AD, Barton MC
Molecular and cellular biology 2014 Jul;34(14):2695-709
Molecular and cellular biology 2014 Jul;34(14):2695-709
Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.
Li KC, Hua KT, Lin YS, Su CY, Ko JY, Hsiao M, Kuo ML, Tan CT
Molecular cancer 2014 Jul 15;13:172
Molecular cancer 2014 Jul 15;13:172
Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells.
Akdemir KC, Jain AK, Allton K, Aronow B, Xu X, Cooney AJ, Li W, Barton MC
Nucleic acids research 2014 Jan;42(1):205-23
Nucleic acids research 2014 Jan;42(1):205-23
Expression of lysophosphatidic acid receptors in the human lower esophageal sphincter.
Feng Y, Liu JF
Experimental and therapeutic medicine 2014 Feb;7(2):423-428
Experimental and therapeutic medicine 2014 Feb;7(2):423-428
Tumor necrosis factor suppresses NR5A2 activity and intestinal glucocorticoid synthesis to sustain chronic colitis.
Huang SC, Lee CT, Chung BC
Science signaling 2014 Feb 25;7(314):ra20
Science signaling 2014 Feb 25;7(314):ra20
The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression.
Kuo YY, Hou HA, Chen YK, Li LY, Chen PH, Tseng MH, Huang CF, Lee FY, Liu MC, Liu CW, Chou WC, Liu CY, Tang JL, Yao M, Tien HF
Haematologica 2014 Dec;99(12):1799-807
Haematologica 2014 Dec;99(12):1799-807
MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis.
Chen PH, Shih CM, Chang WC, Cheng CH, Lin CW, Ho KH, Su PC, Chen KC
Journal of neurochemistry 2014 Dec;131(6):731-42
Journal of neurochemistry 2014 Dec;131(6):731-42
Nitric oxide plays a dual role in the oxidative injury of cultured rat microglia but not astroglia.
Wang JY, Lee CT, Wang JY
Neuroscience 2014 Dec 5;281:164-77
Neuroscience 2014 Dec 5;281:164-77
Deactivation of TBP contributes to SCA17 pathogenesis.
Hsu TC, Wang CK, Yang CY, Lee LC, Hsieh-Li HM, Ro LS, Chen CM, Lee-Chen GJ, Su MT
Human molecular genetics 2014 Dec 20;23(25):6878-93
Human molecular genetics 2014 Dec 20;23(25):6878-93
Identification of a membrane-targeting domain of the transient receptor potential canonical (TRPC)4 channel unrelated to its formation of a tetrameric structure.
Myeong J, Kwak M, Hong C, Jeon JH, So I
The Journal of biological chemistry 2014 Dec 12;289(50):34990-5002
The Journal of biological chemistry 2014 Dec 12;289(50):34990-5002
PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells.
Sanjiv K, Chen CW, Kakadiya R, Tala S, Suman S, Wu MH, Chen YH, Su TL, Lee TC
Translational oncology 2014 Apr;7(2):256-266.e5
Translational oncology 2014 Apr;7(2):256-266.e5
Proliferative effects of melatonin on Schwann cells: implication for nerve regeneration following peripheral nerve injury.
Chang HM, Liu CH, Hsu WM, Chen LY, Wang HP, Wu TH, Chen KY, Ho WH, Liao WC
Journal of pineal research 2014 Apr;56(3):322-32
Journal of pineal research 2014 Apr;56(3):322-32
Oligomerization-induced conformational change in the C-terminal region of Nel-like molecule 1 (NELL1) protein is necessary for the efficient mediation of murine MC3T3-E1 cell adhesion and spreading.
Nakamura Y, Hasebe A, Takahashi K, Iijima M, Yoshimoto N, Maturana AD, Ting K, Kuroda S, Niimi T
The Journal of biological chemistry 2014 Apr 4;289(14):9781-94
The Journal of biological chemistry 2014 Apr 4;289(14):9781-94
Inhibitory effect of litchi (Litchi chinensis Sonn.) flower on lipopolysaccharide-induced expression of proinflammatory mediators in RAW264.7 cells through NF-κB, ERK, and JAK2/STAT3 inactivation.
Yang DJ, Chang YY, Lin HW, Chen YC, Hsu SH, Lin JT
Journal of agricultural and food chemistry 2014 Apr 16;62(15):3458-65
Journal of agricultural and food chemistry 2014 Apr 16;62(15):3458-65
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
Stribl C, Samara A, Trümbach D, Peis R, Neumann M, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Rathkolb B, Wolf E, Beckers J, Horsch M, Neff F, Kremmer E, Koob S, Reichert AS, Hans W, Rozman J, Klingenspor M, Aichler M, Walch AK, Becker L, Klopstock T, Glasl L, Hölter SM, Wurst W, Floss T
The Journal of biological chemistry 2014 Apr 11;289(15):10769-84
The Journal of biological chemistry 2014 Apr 11;289(15):10769-84
Polysaccharides Reduce Lipopolysaccharide-Induced Interleukin-1 Expression in Cultured Smooth Muscle Cells and in Thoracic Aortas in Mice
Liang C, Lee C, Sung H, Chen Y, Chiang Y, Hsu H, Tseng Y, Li C, Wang S, Chen Y
Evidence-Based Complementary and Alternative Medicine 2014 ;2014
Evidence-Based Complementary and Alternative Medicine 2014 ;2014
HIF1-α-mediated gene expression induced by vitamin B1 deficiency.
Sweet RL, Zastre JA
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2013;83(3):188-97
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2013;83(3):188-97
2-methoxyestradiol induces mitotic arrest, apoptosis, and synergistic cytotoxicity with arsenic trioxide in human urothelial carcinoma cells.
Kuo KL, Lin WC, Ho IL, Chang HC, Lee PY, Chung YT, Hsieh JT, Pu YS, Shi CS, Huang KH
PloS one 2013;8(8):e68703
PloS one 2013;8(8):e68703
HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?
Guibinga GH, Murray F, Barron N
PloS one 2013;8(5):e63333
PloS one 2013;8(5):e63333
MicroRNA-449a enhances radiosensitivity in CL1-0 lung adenocarcinoma cells.
Liu YJ, Lin YF, Chen YF, Luo EC, Sher YP, Tsai MH, Chuang EY, Lai LC
PloS one 2013;8(4):e62383
PloS one 2013;8(4):e62383
Anti-Bladder-Tumor Effect of Baicalein from Scutellaria baicalensis Georgi and Its Application In Vivo.
Wu JY, Tsai KW, Li YZ, Chang YS, Lai YC, Laio YH, Wu JD, Liu YW
Evidence-based complementary and alternative medicine : eCAM 2013;2013:579751
Evidence-based complementary and alternative medicine : eCAM 2013;2013:579751
Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents.
Cheng AN, Jiang SS, Fan CC, Lo YK, Kuo CY, Chen CH, Liu YL, Lee CC, Chen WS, Huang TS, Wang TY, Lee AY
Cancer letters 2013 Sep 1;337(2):218-25
Cancer letters 2013 Sep 1;337(2):218-25
Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease.
Fujii W, Kawasaki K, Sugiura K, Naito K
Nucleic acids research 2013 Nov;41(20):e187
Nucleic acids research 2013 Nov;41(20):e187
High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease.
Chen JY, Chou HC, Chen YH, Chan HL
The Journal of nutritional biochemistry 2013 Nov;24(11):1889-910
The Journal of nutritional biochemistry 2013 Nov;24(11):1889-910
Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.
Koriyama Y, Nakayama Y, Matsugo S, Kato S
Brain research 2013 Mar 7;1499:145-57
Brain research 2013 Mar 7;1499:145-57
Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.
Cheng CW, Kuo CY, Fan CC, Fang WC, Jiang SS, Lo YK, Wang TY, Kao MC, Lee AY
Cell death & disease 2013 Jun 20;4:e681
Cell death & disease 2013 Jun 20;4:e681
The synthetic flavonoid WYC02-9 inhibits colorectal cancer cell growth through ROS-mediated activation of MAPK14 pathway.
Chen YJ, Chen HP, Cheng YJ, Lin YH, Liu KW, Chen YJ, Hou MF, Wu YC, Lee YC, Yuan SS
Life sciences 2013 Jun 13;92(22):1081-92
Life sciences 2013 Jun 13;92(22):1081-92
Proteomic analysis of retinopathy-related plasma biomarkers in diabetic patients.
Lu CH, Lin ST, Chou HC, Lee YR, Chan HL
Archives of biochemistry and biophysics 2013 Jan 15;529(2):146-56
Archives of biochemistry and biophysics 2013 Jan 15;529(2):146-56
Postoperative impairment of cognitive function in old mice: a possible role for neuroinflammation mediated by HMGB1, S100B, and RAGE.
Li RL, Zhang ZZ, Peng M, Wu Y, Zhang JJ, Wang CY, Wang YL
The Journal of surgical research 2013 Dec;185(2):815-24
The Journal of surgical research 2013 Dec;185(2):815-24
Evaluation of arginine deiminase treatment in melanoma xenografts using (18)F-FLT PET.
Stelter L, Fuchs S, Jungbluth AA, Ritter G, Longo VA, Zanzonico P, Raschzok N, Sauer IM, Bomalaski JS, Larson SM
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2013 Dec;15(6):768-75
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2013 Dec;15(6):768-75
The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling.
Chen YJ, Cheng YJ, Hung AC, Wu YC, Hou MF, Tyan YC, Yuan SS
Gynecologic oncology 2013 Dec;131(3):734-43
Gynecologic oncology 2013 Dec;131(3):734-43
Effects of cadmium chloride on the cultured human lens epithelial cells.
Song NH, Koh JW
Molecular vision 2012;18:983-8
Molecular vision 2012;18:983-8
Role of MRE11 in cell proliferation, tumor invasion, and DNA repair in breast cancer.
Yuan SS, Hou MF, Hsieh YC, Huang CY, Lee YC, Chen YJ, Lo S
Journal of the National Cancer Institute 2012 Oct 3;104(19):1485-502
Journal of the National Cancer Institute 2012 Oct 3;104(19):1485-502
p38 mitogen-activated protein kinase and PI3-kinase are involved in up-regulation of mu opioid receptor transcription induced by cycloheximide.
Kim DK, Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH
Journal of neurochemistry 2011 Mar;116(6):1077-87
Journal of neurochemistry 2011 Mar;116(6):1077-87
Id1 promotes lung cancer cell proliferation and tumor growth through Akt-related pathway.
Cheng YJ, Tsai JW, Hsieh KC, Yang YC, Chen YJ, Huang MS, Yuan SS
Cancer letters 2011 Aug 28;307(2):191-9
Cancer letters 2011 Aug 28;307(2):191-9
No comments: Submit comment
Enhanced validation
Supportive validation
- Submitted by
- GeneTex (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) 293T whole cell extracts (10 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with beta Actin antibody (GTX109639) diluted at 1:15000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: 293T B: A431 C: Jurkat D: Raji 10% SDS PAGE GTX109639 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- beta Actin antibody detects ACTB protein by western blot analysis.A. 50 ?g mouse brain lysate/extractB. 50 ?g mouse kidney lysate/extractC. 50 ?g mouse lung lysate/extractD. 50 ?g mouse testis lysate/extract10% SDS-PAGEbeta Actin antibody (GTX109639) dilution: 1:10000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (whole cell lysate) A: Candida albicans (sc5314) 20ug B: Candida albicans (sc5314) 40ug 10% SDS PAGE GTX109639 diluted at 1:4000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: Jurkat B: Raji C: 293T D: A431 E: HeLa F: HepG2 G: H1299 H: HCT116 I: MCF-7 J: NT2D1 K: PC-3 L: U87-MG 10% SDS PAGE GTX109639 diluted at 1:10000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- beta Actin antibody detects ACTB protein by western blot analysis.A. 30 ?g PC-12 whole cell lysate/extractB. 30 ?g Rat-2 whole cell lysate/extract10% SDS-PAGEbeta Actin antibody (GTX109639) dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: 293T B: NTH-3T3 C: mouse brain D: PC-12 E: Rat brain F: drosophila 10% SDS PAGE GTX109639 diluted at 1:10000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (whole cell lysate) A: 293T 20ug B: 293T 10ug C: 293T 5ug D: 293T 1ug 10% SDS PAGE GTX109639 diluted at 1:5000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (10 ?g of whole cell lysate) A: Yeast lysate 7.5% SDS PAGE GTX109639 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Non-transfected (¡V) and transfected (+) 293T whole cell extracts (10 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with beta Actin antibody (GTX109639) diluted at 1:15000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using beta Actin(GTX109639) antibody (Green) at 1:200 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of methanol-fixed HeLa, using Beta-actin (GTX109639) antibody at 1:500 dilution.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using Beta actin(GTX109639) antibody at 1:100 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- beta Actin antibody detects beta Actin protein at cytoplasm in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. beta Actin antibody (GTX109639) diluted at 1:500.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- beta Actin antibody detects beta Actin protein at cytoplasm in rat testis by immunohistochemical analysis. Sample: Paraffin-embedded rat testis. beta Actin antibody (GTX109639) diluted at 1:500.