Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-13012 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Beta actin Antibody
- Antibody type
- Polyclonal
- Description
- B-actin (ACTB) has traditionally been regarded as an endogenous housekeeping gene and has been widely used as a reference gene/protein in quantifying expression levels in tumors. It supports fundamental cellular processes in healthy and diseased cells including cell adhesion, migration, cytokinesis and maintenance of cell polarity. However, B-actin is closely associated with a variety of cancers and accumulating evidence indicates that B-actin is de-regulated in liver, melanoma, renal, colorectal, gastric, pancreatic, esophageal, lung, breast, prostate, ovarian cancers, leukemia and lymphoma. This protein is generally found to be up-regulated in the majority of tumor cells and tissues.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Antigen sequence
A partial length recombinant Beta a
ctin protein (amino acids 1-200) wa
s used as the immunogen for this an
tibody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Beta actin. Anti- Beta actin antibody (11-13012) was used at 4 µg/ml on 1) Raw, 2) 3T3, 3) Hela and 4) U87 lysates.