315204

antibody from BioLegend
Targeting: SPN CD43, GPL115, LSN
Provider product page for 315204

Antibody data

Product number
315204 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#315204, RRID:AB_389247
Product name
FITC anti-human CD43
Antibody type
Monoclonal
Antigen
Human T lymphocytes
Description
CD43 is a 95-135 kD type I transmembrane glycoprotein known as leukosialin, leukocyte sialoglycoprotein, sialophorin, and galactoglyprotein. It is expressed at high levels on the surface of all leukocytes (except on resting B cells) and at low levels on platelets, negative on erythrocytes. The expression of CD43 on T cells and neutrophils is rapidly downregulated by proteolytic shedding after activation with various stimuli. The soluble form of CD43 is present in human serum. It has been reported that CD43 plays a role in anti-adhesive functions, but also mediates adhesion via its interaction with CD54 or some lectins. Similarly, CD43 is implicated in anti-apoptotic and proapoptotic signaling.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
SPN protein structure - 315204 shown in red.