BS3550

antibody from Bioworld Technology, Inc

Targeting: APOE AD2

Immunohistochemistry

Antibody data

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Validation data

Product number: BS3550 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS3550, RRID:AB_1662720
Product name: ApoE (M86) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 51-100 of Human ApoE.
Description: Apolipoprotein-E (ApoE) is a protein component of plasma lipoproteins that mediates the binding, internalization and catabolism of lipoprotein particles. It can serve as a ligand for several lipoprotein receptors, including the LDL (apoB/E) receptor and the hepatic apoE (chylomicron remnant) receptor. apoE is produced in most organs and occurs in all plasma lipoprotein fractions, constituting 10-20% of VLDL (very low density lipoprotein) and 1-2% of HDL (high density lipoprotein). Three major isoforms of apoE have been described in human (E2, E3 and E4) which differ by one to two amino acids. Estrogen receptor has been shown to upregulate apoE gene expression via the ERamediated pathway, indicating a potential role for apoE in atherosclerosis.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

APOE protein structure - BS3550 shown in red.