BS8161

antibody from Bioworld Technology, Inc
Targeting: DBN1 D0S117E
Provider product page for BS8161
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8161 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DBN1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DBN1.
Description
Drebrins (Developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes, and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A) that are generated by alternative RNA splicing from a single Debrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas, and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain are associated with Alzheimer£ªs disease and Down syndrome. The gene encoding for the human Drebrin protein is located on chromosome 5.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DBN1 protein structure - BS8161 shown in red.