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- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 15518-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15518-1-AP, RRID:AB_2263448
- Product name
- Beta Galactosidase antibody
- Antibody type
- Polyclonal
- Description
- Beta Galactosidase antibody (Cat. #15518-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Heat shock protein A12B gene therapy improves perfusion, promotes neovascularization, and decreases fibrosis in a murine model of hind limb ischemia.
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention.
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation.
Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
Galactose-modified duocarmycin prodrugs as senolytics.
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Cardiac glycosides are broad-spectrum senolytics.
Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways.
β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
Thirunavukkarasu M, Tipu Rishi M, Pradeep SR, Swaminathan S, Accorsi D, Palesty JA, Maulik N
Surgery 2021 Sep;170(3):969-977
Surgery 2021 Sep;170(3):969-977
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention.
Vignoli B, Sansevero G, Sasi M, Rimondini R, Blum R, Bonaldo V, Biasini E, Santi S, Berardi N, Lu B, Canossa M
Communications biology 2021 Oct 5;4(1):1152
Communications biology 2021 Oct 5;4(1):1152
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Tian J, Cheng C, Kuang SD, Su C, Zhao X, Xiong YL, Li YS, Gao SG
Pain research & management 2020;2020:3428587
Pain research & management 2020;2020:3428587
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y
Theranostics 2020;10(15):6839-6853
Theranostics 2020;10(15):6839-6853
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Balakrishnan I, Danis E, Pierce A, Madhavan K, Wang D, Dahl N, Sanford B, Birks DK, Davidson N, Metselaar DS, Meel MH, Lemma R, Donson A, Vijmasi T, Katagi H, Sola I, Fosmire S, Alimova I, Steiner J, Gilani A, Hulleman E, Serkova NJ, Hashizume R, Hawkins C, Carcaboso AM, Gupta N, Monje M, Jabado N, Jones K, Foreman N, Green A, Vibhakar R, Venkataraman S
Cell reports 2020 Oct 20;33(3):108286
Cell reports 2020 Oct 20;33(3):108286
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation.
Shen L, Kang L, Wang D, Xun J, Chen C, Du L, Zhang M, Gong J, Mi X, Yue S, Zhang Y, Song X, Xiang R, Zhang Z, Tan X
Cancer letters 2020 Mar 1;472:40-49
Cancer letters 2020 Mar 1;472:40-49
Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
Xu P, Xin Y, Zhang Z, Zou X, Xue K, Zhang H, Zhang W, Liu K
Stem cell research & therapy 2020 Jul 1;11(1):264
Stem cell research & therapy 2020 Jul 1;11(1):264
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, Guo Y, Lin Y, Li L, Yu X, Liu T, Zhao Y
Aging 2020 Jan 6;12(1):650-671
Aging 2020 Jan 6;12(1):650-671
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
Shang GK, Han L, Wang ZH, Liu YP, Yan SB, Sai WW, Wang D, Li YH, Zhang W, Zhong M
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
Journal of cachexia, sarcopenia and muscle 2020 Aug;11(4):1104-1120
Galactose-modified duocarmycin prodrugs as senolytics.
Guerrero A, Guiho R, Herranz N, Uren A, Withers DJ, Martínez-Barbera JP, Tietze LF, Gil J
Aging cell 2020 Apr;19(4):e13133
Aging cell 2020 Apr;19(4):e13133
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Li Y, Li X, Cao M, Jiang Y, Yan J, Liu Z, Yang R, Chen X, Sun P, Xiang R, Wang L, Shi Y
Signal transduction and targeted therapy 2019;4:50
Signal transduction and targeted therapy 2019;4:50
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J
Nature metabolism 2019 Nov;1(11):1074-1088
Nature metabolism 2019 Nov;1(11):1074-1088
Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways.
Wu Y, Cai Q, Li W, Cai Z, Liu Y, Li H, Pang J, Chen Y
Bioscience reports 2019 Aug 30;39(8)
Bioscience reports 2019 Aug 30;39(8)
β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.
Turlo KA, Scapa J, Bagher P, Jones AW, Feil R, Korthuis RJ, Segal SS, Iruela-Arispe ML
Arteriosclerosis, thrombosis, and vascular biology 2013 Oct;33(10):2325-35
Arteriosclerosis, thrombosis, and vascular biology 2013 Oct;33(10):2325-35
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Büchner N, Ale-Agha N, Jakob S, Sydlik U, Kunze K, Unfried K, Altschmied J, Haendeler J
Experimental gerontology 2013 Jan;48(1):8-16
Experimental gerontology 2013 Jan;48(1):8-16
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
Werner C, Gensch C, Pöss J, Haendeler J, Böhm M, Laufs U
Atherosclerosis 2011 May;216(1):23-34
Atherosclerosis 2011 May;216(1):23-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15518-1-AP(GLB1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using GLB1 antibody 15518-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
