abx001952

antibody from Abbexa

Targeting: GNAO1 G-ALPHA-o

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx001952

Provider

Abbexa

Product name

Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1) Antibody

Antibody type

Polyclonal

Description

GNAO1 Antibody is a Rabbit Polyclonal antibody against GNAO1. Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.