MB0127

antibody from Bioworld Technology, Inc
Targeting: CHRDL1 CHL, MGC1, NRLN1
Provider product page for MB0127

Antibody data

Product number
MB0127 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CHRDL1 monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human CHRDL1.
Description
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
Reactivity
Human, Mouse, Rat
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHRDL1 protein structure - MB0127 shown in red.