APR03693G

antibody from Leading Biology

Targeting: MYBPC3 CMH4, cMyBP-C, FHC

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03693G

Provider

Leading Biology

Product name

MYBPC3 Antibody (N-term)

Antibody type

Polyclonal

Description

MYBPC3 encodes the cardiac isoform of myosin-bindingprotein C. Myosin-binding protein C is a myosin-associated proteinfound in the cross-bridge-bearing zone (C region) of A bands instriated muscle. MYBPC3, the cardiac isoform, is expressedexclussively in heart muscle. Regulatory phosphorylation of thecardiac isoform in vivo by cAMP-dependent protein kinase (PKA) uponadrenergic stimulation may be linked to modulation of cardiaccontraction. Mutations in MYBPC3 are one cause of familialhypertrophic cardiomyopathy.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.