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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- V3364 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Filaggrin Antibody
- Antibody type
- Monoclonal
- Description
- Purified
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- SPM181
- Vial size
- 20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)
- Concentration
- 0.2 mg/ml
- Storage
- Store the Filaggrin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Eczema Is an Independent Risk Factor for Incident Mouse Skin Test Sensitivity Among Employees at a Mouse Production and Research Facility
Expression of Filaggrin in Skin Biopsies: Role in Maintenance of Symptoms Among Brazilian Patients with Moderate-to-Severe Atopic Dermatitis
Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.
IL-33 impacts on the skin barrier by downregulating the expression of filaggrin.
Aberrant expression of caspase 14 in salivary gland carcinomas.
Efficient fabrication of epidermal cell sheets using γ-secretase inhibitor.
Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis.
The effect of Psoroptes ovis infestation on ovine epidermal barrier function.
Expression of caspase 14 and filaggrin in oral squamous carcinoma.
The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability.
IL-17 downregulates filaggrin and affects keratinocyte expression of genes associated with cellular adhesion.
Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis.
Filaggrin Expression in Oral, Nasal, and Esophageal Mucosa
Grant T, Dantzer J, Keet C, Peng R, Krevans M, Hagberg K, Curtin-Brosnan J, Shreffler W, Matsui E
Journal of Allergy and Clinical Immunology 2016 February;137(2)
Journal of Allergy and Clinical Immunology 2016 February;137(2)
Expression of Filaggrin in Skin Biopsies: Role in Maintenance of Symptoms Among Brazilian Patients with Moderate-to-Severe Atopic Dermatitis
Boufleur K, Cardili R, Melo J, Moreno A, Roselino A, Soares E, Arruda L
Journal of Allergy and Clinical Immunology 2016 February;137(2)
Journal of Allergy and Clinical Immunology 2016 February;137(2)
Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.
Shigehara Y, Okuda S, Nemer G, Chedraoui A, Hayashi R, Bitar F, Nakai H, Abbas O, Daou L, Abe R, Sleiman MB, Kibbi AG, Kurban M, Shimomura Y
Human molecular genetics 2016 Aug 18;
Human molecular genetics 2016 Aug 18;
IL-33 impacts on the skin barrier by downregulating the expression of filaggrin.
Seltmann J, Roesner LM, von Hesler FW, Wittmann M, Werfel T
The Journal of allergy and clinical immunology 2015 Jun;135(6):1659-61.e4
The Journal of allergy and clinical immunology 2015 Jun;135(6):1659-61.e4
Aberrant expression of caspase 14 in salivary gland carcinomas.
Lemound J, Stucki-Koch A, Stoetzer M, Kokemüller H, Gellrich NC, Kreipe H, Hussein K
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jul;44(6):444-8
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jul;44(6):444-8
Efficient fabrication of epidermal cell sheets using γ-secretase inhibitor.
Nakajima R, Takeda S
Journal of dermatological science 2014 Dec;76(3):246-54
Journal of dermatological science 2014 Dec;76(3):246-54
Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis.
Matoso A, Mukkada VA, Lu S, Monahan R, Cleveland K, Noble L, Mangray S, Resnick MB
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 May;26(5):665-76
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 May;26(5):665-76
The effect of Psoroptes ovis infestation on ovine epidermal barrier function.
Stoeckli MR, McNeilly TN, Frew D, Marr EJ, Nisbet AJ, van den Broek AH, Burgess ST
Veterinary research 2013 Feb 11;44:11
Veterinary research 2013 Feb 11;44:11
Expression of caspase 14 and filaggrin in oral squamous carcinoma.
Scharenberg C, Eckardt A, Tiede C, Kreipe H, Hussein K
Head and neck pathology 2013 Dec;7(4):327-33
Head and neck pathology 2013 Dec;7(4):327-33
The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability.
Szabo AZ, Fong S, Yue L, Zhang K, Strachan LR, Scalapino K, Mancianti ML, Ghadially R
Stem cells (Dayton, Ohio) 2013 Apr;31(4):786-99
Stem cells (Dayton, Ohio) 2013 Apr;31(4):786-99
IL-17 downregulates filaggrin and affects keratinocyte expression of genes associated with cellular adhesion.
Gutowska-Owsiak D, Schaupp AL, Salimi M, Selvakumar TA, McPherson T, Taylor S, Ogg GS
Experimental dermatology 2012 Feb;21(2):104-10
Experimental dermatology 2012 Feb;21(2):104-10
Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis.
Winge MC, Bilcha KD, Liedén A, Shibeshi D, Sandilands A, Wahlgren CF, McLean WH, Nordenskjöld M, Bradley M
The British journal of dermatology 2011 Nov;165(5):1074-80
The British journal of dermatology 2011 Nov;165(5):1074-80
Filaggrin Expression in Oral, Nasal, and Esophageal Mucosa
De Benedetto A, Qualia C, Baroody F, Beck L
Journal of Investigative Dermatology 2008 June;128(6):1594-1597
Journal of Investigative Dermatology 2008 June;128(6):1594-1597
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of FFPE human skin with Filaggrin antibody (clone SPM181). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
