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- References [6]
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- Product number
- 4308 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#4308, RRID:AB_10547134
- Product name
- Tuberin/TSC2 (D93F12) XP® Rabbit mAb
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Hamster, Simian
- Host
- Rabbit
- Storage
- -20°C
Submitted references Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway.
TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway.
Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H, Cantley LC, Manning BD
Cell 2014 Feb 13;156(4):771-85
Cell 2014 Feb 13;156(4):771-85
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL
Nature cell biology 2013 Oct;15(10):1186-96
Nature cell biology 2013 Oct;15(10):1186-96
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway.
Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, Kitamura M
Cell death and differentiation 2012 Feb;19(2):310-20
Cell death and differentiation 2012 Feb;19(2):310-20
TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC, Elis W, Menon S, Qin W, Klekota J, Asara JM, Finan PM, Kwiatkowski DJ, Murphy LO, Manning BD
Molecular cell 2012 Aug 24;47(4):535-46
Molecular cell 2012 Aug 24;47(4):535-46
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Goto J, Talos DM, Klein P, Qin W, Chekaluk YI, Anderl S, Malinowska IA, Di Nardo A, Bronson RT, Chan JA, Vinters HV, Kernie SG, Jensen FE, Sahin M, Kwiatkowski DJ
Proceedings of the National Academy of Sciences of the United States of America 2011 Nov 8;108(45):E1070-9
Proceedings of the National Academy of Sciences of the United States of America 2011 Nov 8;108(45):E1070-9
Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway.
Park JH, Arakawa-Takeuchi S, Jinno S, Okayama H
The Journal of biological chemistry 2011 Jul 1;286(26):23132-41
The Journal of biological chemistry 2011 Jul 1;286(26):23132-41
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