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- Antigen structure
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- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- MA5-15922 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- MBP Monoclonal Antibody (2H9)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-15922 targets MBP in FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
- Antibody clone number
- 2H9
- Concentration
- Conc. Not Determined
Submitted references Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT(1) receptors.
Metformin exacerbates and simvastatin attenuates myelin damage in high fat diet-fed C57BL/6 J mice.
Edvinsson JCA, Maddahi A, Christiansen IM, Reducha PV, Warfvinge K, Sheykhzade M, Edvinsson L, Haanes KA
The journal of headache and pain 2022 Feb 17;23(1):26
The journal of headache and pain 2022 Feb 17;23(1):26
Metformin exacerbates and simvastatin attenuates myelin damage in high fat diet-fed C57BL/6 J mice.
Ciric D, Martinovic T, Petricevic S, Trajkovic V, Bumbasirevic V, Kravic-Stevovic T
Neuropathology : official journal of the Japanese Society of Neuropathology 2018 Oct;38(5):468-474
Neuropathology : official journal of the Japanese Society of Neuropathology 2018 Oct;38(5):468-474
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of MBP using a MBP monoclonal antibody (Product # MA5-15922) against a human MBP (AA: 1-197) recombinant protein.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of MBP using MBP monoclonal antibody (Product # MA5-15922) in HEK293 (1) and MBP-human IgG Fc transfected HEK293 (2) cell lysate.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of MSCS cells using MBP monoclonal antibody (Product # MA5-15922) (Green). Blue: DRAQ5 fluorescent DNA dye. Red: actin filaments have been labeled with phalloidin.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded brain tissues using MBP monoclonal antibody (Product # MA5-15922) followed with DAB staining.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded cerebellum tissues using MBP monoclonal antibody (Product # MA5-15922) followed with DAB staining.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometric analysis of HepG2 cells using MBP monoclonal antibody (Product # MA5-15922) (green) and negative control (red).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Representative confocal lazer microscopic images of double labeled immunofluorescence-stained sciatic nerve sections for MBP (green) and LC3 (red). White arrow indicates yellow colocalization of MBP and LC3.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Expression of 5-HT in relation to myelin basic protein (MBP), SP and CGRP. A MBP showed a distinct staining of myelin sheath flanking cross-sectioned Adelta-fibre axons. A robust MBP-ir was observed (Arrowhead) between the Adelta-fibre axon and Schwann cell neurolemma. An irregular, and sometimes faint, expression of 5-HT could be observed in Adelta-fibre axons (Asterix) and just outside the myelin sheath (Arrow), indicative for the neurolemma of the Schwann cell containing its cytoplasm. B A minority of observed C-fibres expressed 5-HT-ir, these were more frequently found in proximity to Redlich-Obersteiner's zone. CGRP-ir was more abundantly expressed in C-fibres and did not co-localize with 5-HT. Arrows mark 5-HT positive C-fibre boutons and arrowheads mark CGRP positive C-fibre boutons. Insert: Two thin C-fibres entwining and differentially expressing either CGRP or 5-HT. C Similarly, SP could be found concentrated to C-fibre boutons (Arrowhead) throughout the TG. The few 5-HT positive C-fibres (Arrow) were not found to co-localize with SP positive C-fibres. Insert: A thin C-fibre expressing 5-HT-ir (Arrow) above a seemingly larger SP positive C-fibre (Arrowhead)
