BS7698

antibody from Bioworld Technology, Inc
Targeting: SLPI ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4
Provider product page for BS7698
Western blot
Immunohistochemistry

Antibody data

Product number
BS7698 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SLPI polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SLPI.
Description
SLPI, secretory leukocyte protease inhibitor, is an enzyme that belongs to the Ï«-1 antitrypsin antiprotein family. Produced by epithelial cells, SLPI resides in parotid secretions, bronchial, nasal and cervical mucus, and seminal fluid. SLPI plays a primary role in the regulation of neutrophil-mediated inflammation. It does so through proteolysis and subsequent inhibition of the leukocyte serine proteases, including the neutrophil and pancreatic proteases. The promoter region of SLPI has been identified as binding site for IRF-1, interferon regulatory factor. Expression of SLPI is inhibited by IRF-1 co-expression, identifying SLPI as a target of IRF-1 regulation. SLPI also functions as a macrophage derived inhibitor of macrophage response to LPS by inhibiting the production of nitric oxide, which suggests the role of SLPI in LPS tolerance.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SLPI protein structure - BS7698 shown in red.